Appropriate Solutions
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Terms in this set (208)
HIV virus type RNA retrovirus that attacks CD4 T-helper cells
AIDS diagnosis CD4 count <200 OR AIDS-defining illness
GP120 function Viral binding to CD4 receptor
GP41 function Viral fusion with host cell
Reverse transcriptase Converts viral RNA into DNA
Integrase Inserts viral DNA into host genome
HIV testing step 1 HIV 1/2 antigen-antibody immunoassay (p24 antigen)
HIV testing step 2 HIV 1/HIV 2 differentiation assay
Opportunistic infection PCP treatment Bactrim
Kaposi sarcoma cause HHV-8 in immunocompromised patients
CCR5 antagonist example Maraviroc
Maraviroc side effects Orthostatic hypotension, hepatotoxicity
Fusion inhibitor example Enfuvirtide
Enfuvirtide side effect Injection site reactions
, NRTI example Abacavir
Abacavir warning Never rechallenge due to fatal hypersensitivity
AZT side effects Anemia, neutropenia, bone marrow suppression
Didanosine side effects Pancreatitis, peripheral neuropathy
NNRTI example Nevirapine
Nevirapine side effects Hepatotoxicity, SJS/TEN
Integrase inhibitor example Raltegravir
Raltegravir side effect Elevated CK, myopathy
Protease inhibitor example Saquinavir
Protease inhibitor side effects Hyperglycemia, lipodystrophy, hyperlipidemia
Dronabinol purpose Appetite stimulant in HIV patients
Type I hypersensitivity IgE mediated immediate reaction
Anaphylaxis first-line treatment IM epinephrine 1:1000
Epinephrine injection site Vastus lateralis (outer thigh)
Type II hypersensitivity IgG/IgM cytotoxic reaction
Type III hypersensitivity Immune complex deposition in joints/kidneys
Type IV hypersensitivity Delayed reaction 24-72 hours
Elevated in allergic reactions IgE and eosinophils