RN PHARMACOLOGY NCLEX-STYLE
QUESTIONS — COMPREHENSIVE Q&A 2026
EDITION
◉enoxaparin. Answer: low molecular weight heparin; indirect
inhibitor, a shorter form of heparin, can be given using a fixed dose
with no aPTT monitoring. Inactivates ONLY Xa. subQ only. Can be
used at home.
◉exenatide. Answer: incretin mimetic; Activates receptors for GLP-
1. Increases insulin secretion; slows GI absorption of glucose and
gastric emptying. [-ide, acts similar to tolbutamide]
◉fexofenadine. Answer: 2nd gen antihistamine, H1 competitive
antagonist (allegra), lesser sedative effects
◉dopamine. Answer: "Inotropic agent that requires constant
BP/EKG monitoring. Activates beta1 AR in heart and increases
contractility and HR (risk of tachycardia). Dilates renal blood vessels
and increases urine output via receptor activation in the kidney
,◉erythromycin. Answer: Macrolid; Static, narrow (G+), inhibits
protein synthesis
SEs: GI; DDIs with 3A4 inhibitors (cardiotoxic) and antidysrythmics"
◉furosemide. Answer: Loop diuretic. Site of action in the nephron is
the Loop of Henley. Can cause hypokalemia. Diuretics increase the
risk of dysrhythmias in a patient taking digoxin by promoting
potassium loss.
Used for HTN and HF. Works with low GFR.
◉gemfibrozil. Answer: fibroacid derivative, lowers triglycerides
◉gentamicin. Answer: Cidal, narrow (G-)--> ONLY ONE. Lethal
inhibition of protien synthesis (ONLY ONE THAT DOES THIS).
SE: Ototoxic (High pitch tinnitus and headache), Kidney problems
(nephrotoxicity). Hypersensitivity, Neuro-mm'r blockade=resp.
depression. KNOW THESE GENTAMICIN SEs."
◉glucagon. Answer: treats hypoglycemia; carbohydrate; opposite
effects of insulin
◉glyburide. Answer: 2nd generation sulfonylurea; stimulates insulin
release in pancreas; Same as Tolbutamide, but more potent. [-ide];
, ◉haloperidol. Answer: FGA, high potency; treats positive symptoms.
SE: EPS (Acute-dystonia, parkinsons-like, akathesia and Late-
Tardive Dyskinesia) and NMS. Immediate effects. Only used in
emergent situation, b/c of SE
◉heparin. Answer: "Rapid-acting anticoagulant that enhances
activity of antithrombin and inactivates clotting factors. It is used in
treating pulmonary embolism, evolving stroke, and prevention of
vein thrombosis. Its adverse effects include hemorrhage, drug-
induced thrombocytopenia, and hypersensitivity reactions.
◉hydralazine. Answer: a vasodilator that directly dilates arterioles.
It may produce SEs including systemic lupus erythematosus-like
syndrome, reflex tachycardia, and increased blood volume; BB can
prevent tachycardia
◉hydrocodone/acetaminophen. Answer: opioid and non opioid
combined for analgesia
◉hydrochlorothiazide. Answer: Thiazide diuretic. Site of action in
the nephron is the Distal Convoluted Tubule. First line of treatment
for patients without compelling indications. Can cause hypokalemia.
Does not work with low GFR. Also used for HF.
QUESTIONS — COMPREHENSIVE Q&A 2026
EDITION
◉enoxaparin. Answer: low molecular weight heparin; indirect
inhibitor, a shorter form of heparin, can be given using a fixed dose
with no aPTT monitoring. Inactivates ONLY Xa. subQ only. Can be
used at home.
◉exenatide. Answer: incretin mimetic; Activates receptors for GLP-
1. Increases insulin secretion; slows GI absorption of glucose and
gastric emptying. [-ide, acts similar to tolbutamide]
◉fexofenadine. Answer: 2nd gen antihistamine, H1 competitive
antagonist (allegra), lesser sedative effects
◉dopamine. Answer: "Inotropic agent that requires constant
BP/EKG monitoring. Activates beta1 AR in heart and increases
contractility and HR (risk of tachycardia). Dilates renal blood vessels
and increases urine output via receptor activation in the kidney
,◉erythromycin. Answer: Macrolid; Static, narrow (G+), inhibits
protein synthesis
SEs: GI; DDIs with 3A4 inhibitors (cardiotoxic) and antidysrythmics"
◉furosemide. Answer: Loop diuretic. Site of action in the nephron is
the Loop of Henley. Can cause hypokalemia. Diuretics increase the
risk of dysrhythmias in a patient taking digoxin by promoting
potassium loss.
Used for HTN and HF. Works with low GFR.
◉gemfibrozil. Answer: fibroacid derivative, lowers triglycerides
◉gentamicin. Answer: Cidal, narrow (G-)--> ONLY ONE. Lethal
inhibition of protien synthesis (ONLY ONE THAT DOES THIS).
SE: Ototoxic (High pitch tinnitus and headache), Kidney problems
(nephrotoxicity). Hypersensitivity, Neuro-mm'r blockade=resp.
depression. KNOW THESE GENTAMICIN SEs."
◉glucagon. Answer: treats hypoglycemia; carbohydrate; opposite
effects of insulin
◉glyburide. Answer: 2nd generation sulfonylurea; stimulates insulin
release in pancreas; Same as Tolbutamide, but more potent. [-ide];
, ◉haloperidol. Answer: FGA, high potency; treats positive symptoms.
SE: EPS (Acute-dystonia, parkinsons-like, akathesia and Late-
Tardive Dyskinesia) and NMS. Immediate effects. Only used in
emergent situation, b/c of SE
◉heparin. Answer: "Rapid-acting anticoagulant that enhances
activity of antithrombin and inactivates clotting factors. It is used in
treating pulmonary embolism, evolving stroke, and prevention of
vein thrombosis. Its adverse effects include hemorrhage, drug-
induced thrombocytopenia, and hypersensitivity reactions.
◉hydralazine. Answer: a vasodilator that directly dilates arterioles.
It may produce SEs including systemic lupus erythematosus-like
syndrome, reflex tachycardia, and increased blood volume; BB can
prevent tachycardia
◉hydrocodone/acetaminophen. Answer: opioid and non opioid
combined for analgesia
◉hydrochlorothiazide. Answer: Thiazide diuretic. Site of action in
the nephron is the Distal Convoluted Tubule. First line of treatment
for patients without compelling indications. Can cause hypokalemia.
Does not work with low GFR. Also used for HF.
