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(Actual Exam) 2025\2026
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What are the three major hypotheses of psychosis and their
neurotransmitter networks? - 🧠 ANSWER ✔✔Dopamine theory -
hyperactive dopamine at D2 receptors in the mesolimbic pathway
Glutamate theory - NMDA receptor hypofunction
Serotonin theory - 5HT2A receptor hyperfunction in the cortex
, Briefly explain the dopamine hypothesis of the positive and negative
symptoms of schizophrenia. - 🧠 ANSWER ✔✔The dopamine hypothesis of
schizophrenia consists of:
There is too much dopamine activity in the mesolimbic dopamine pathway,
which leads to positive symptoms (such as hallucinations and delusions).
There is also too little dopamine activity in the mesocortical dopamine
pathway, which leads to negative symptoms (such as blunting of affect,
poverty of speech, anhedonia, and so on).
What pathway is responsible for regulating dopamine in the hypothalamus
and affects the release of prolactin? - 🧠 ANSWER ✔✔Tuberoinfundibular
pathway
Drug-induced Parkinson's is caused by a decrease of dopamine in what
pathway? - 🧠 ANSWER ✔✔Nigrostriatal pathway
Brodmann's areas are differentiated by the: - 🧠 ANSWER ✔✔Cellular
architecture
All of the following are true about the hippocampus except that it: - 🧠
ANSWER ✔✔Is disrupted by frontal lobotomy