NUR 334 Exam 4
What is the difference between H1 and H2 blockers? - answer
What medications fall into the H2 receptor antagonists - answerfamotidine, cimetidine,
nizatidine
What are proton pump inhibitors? (MOA) - answerprofound and prolonged reduction of
stomach acid production by irreversibly inhibiting the stomach's hydrogen and
potassium ATPase proton pump. MOST POTENT inhibitors.
What are PPI's used to treat? - answerGERD, ulcers, H. pylori
What are the mucosal protective agents? - answerBismuth-Salicylate
Misoprostol (Prostaglandin analogues)
Sucralfate
How do mucosal protectants work? - answerCreates a protective barrier over ulcers and
erosions to limit the access against acid and pepsin
*must have an acidic environment to work
What is the MOA of antacids? - answerdecreased intragastric acidity by *reacting with
gastric HCl to form a salt and water*
What drugs are antacids? - answeraluminum hydroxide
calcium carbonate
magnesium hydroxide
sodium bicarbonate
What is a nursing consideration for antacids? - answerincreased effectiveness for
levodopa and pseudoephedrine; decreased antibiotic effectiveness
What is the desired effect of antiemetics? - answerreduce nausea and vomiting
What medications fall into the antiemetic category? - answerondansetron (zofran)
promethazine (phenergan)
metoclopramide (reglan)
meclizine (over the counter)
bismuth subsalicylate (pepto-bismol)
What is the effect of laxatives? - answerloosen stools and increase bowel movements
What is the difference between H1 and H2 blockers? - answer
What medications fall into the H2 receptor antagonists - answerfamotidine, cimetidine,
nizatidine
What are proton pump inhibitors? (MOA) - answerprofound and prolonged reduction of
stomach acid production by irreversibly inhibiting the stomach's hydrogen and
potassium ATPase proton pump. MOST POTENT inhibitors.
What are PPI's used to treat? - answerGERD, ulcers, H. pylori
What are the mucosal protective agents? - answerBismuth-Salicylate
Misoprostol (Prostaglandin analogues)
Sucralfate
How do mucosal protectants work? - answerCreates a protective barrier over ulcers and
erosions to limit the access against acid and pepsin
*must have an acidic environment to work
What is the MOA of antacids? - answerdecreased intragastric acidity by *reacting with
gastric HCl to form a salt and water*
What drugs are antacids? - answeraluminum hydroxide
calcium carbonate
magnesium hydroxide
sodium bicarbonate
What is a nursing consideration for antacids? - answerincreased effectiveness for
levodopa and pseudoephedrine; decreased antibiotic effectiveness
What is the desired effect of antiemetics? - answerreduce nausea and vomiting
What medications fall into the antiemetic category? - answerondansetron (zofran)
promethazine (phenergan)
metoclopramide (reglan)
meclizine (over the counter)
bismuth subsalicylate (pepto-bismol)
What is the effect of laxatives? - answerloosen stools and increase bowel movements
