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Anti-Hypertensive Drugs Summary - Pharmacology (Pharm-D Level)

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Anti-hypertensive drugs, Beta Blockers, ACE Inhibitors, Diuretics, Calcium Channel Blockers, Hypertension Treatment, Pharm-D Notes, Cardiovascular Drugs, Medical Summary

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E Mail- & Reach solution at- www.facebook.com/pharmavideo/

Anti-Hypertensive Drugs
Prevention is always better than cure

Classification- KD Tripathi


1 2 3 4 5 6 7 8 9

ACE Angiotensin Calcium Channel Beta+Alfa Alfa Central
Diuretics Blocker Blocker Beta Blocker Blocker Blocker Sympatholytics Vasodilator
Inhibitor




Examples of above listed Class Thiazide Diuretics Channel is closed

Channel is Open
Thiazide- Hydrochlorothiazide, Chlorthiazide, Indapamide Increase Water & Sodium Excretion
High Ceiling- Furosemide
K+ Sparing- Spironelactone, Amiloride


Captopril, Enalapril, Linsopril, Perindopril, Short Term Effect Long Term Effect
Ramipril, Fosinopril etc.


Decrease Blood Volume Channel isDecrease
Open Sodium content in cell
Losartan, Candesartan, Irbesartan, Valsartan, Telmisartan 04

Verapamil, Diltiazem, Nifedipin, Felodipine,
Decrease cardiac output Decrease Calcium channel Blocker
Muscles sensitivity to vasopresser
Amlodipine, Lacidipine


Decrease Peripheral Resistance
Propranolol, Metoprolol, Atenolol Increase
01
Heart rate
Contractility
Labetalol, Carvedilol Conduction
Decrease Blood Pressure

Beta Receptor Blocker 05
Prazocin, Terazocin, Doxazosin, Angiotensinogen
Phentolamine, Phenoxybenzamine
Renin from Kidney Decrease output of Symp. Nervous system
Blood
Clonidine, Methyldopa Angiotensin I Increase vasodilatation of vascular muscle Pressure
(Inactive) Angiotensin II


Arteriolar- Hydralazine, Minoxidil, Diazoxide Decrease sod. And water retention
Arteriolar+ Venous- Sodium Nitropruside ACE Inhibitors Aldosterone Production


All diagrams and design- Solution-Pharmacy Angiotensin Blockers 02 03 www.facebook.com/pharmavideo/

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