3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
N5334 Final Exam Questions & Answers Test
QUESTIONS AND VERIFIED SOLUTIONS |2026|
ELABORATED &DETAILED ANSWERS!!
Save
Terms in this set (323)
Prescribing basics Prescribing is regulated by state BON
Proper RX Providers name and address, Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with
indication/Route and frequency, Quantity and
signature.
Drug Schedules: Most addictive to 1: Heroin,LSD, MJ
least 2: hydrocodone, cocaine, Methamphetamine,
methadone, oxycodone, meperidine, fentanyl,
adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics The effects of drug on the body. Receptors are
large molecules usually proteins, that interact and
mediate the action of drugs
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,3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
agonist produce receptor stimulation and a conformational
change every time they bind. Do not need all
available receptors to produce a maximum
response
Partial agonist drugs that have properties in b/w those of full
agonist and antagonist. They bind to receptors but
when they occupy the receptor sites, they stimulate
only some of the receptors.
antagonist drugs with affinity for a receptor but with no
intrinsic activity. Affinity allows the antagonist to
bind to receptors, but lack of intrinsic activity
prevents the bound antagonist from causing
receptor activation. The block action of drugs (ex.
Narcan)
Bioavailabity % of administered dosage of the drug that survives
the first pass through the liver and reaches the
blood stream
half life Time required for the amount of a drug in the body
to decline by 50%, drugs with shorter half lives
must be administer frequently. 4.5-5.5 times the half
life to get steady state and to be limited from the
body
what the body does to the drug absorption, distribution, metabolism, excretion
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,3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
Distribution movement of absorbed drug in bodily fluids
throughout the body to target tissue. Properties
affecting: lipid/water solubility, PH affects
ionization of drug, protein binding, size of
molecule (smaller molecules are more able to
diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid
soluble will pass), placental barrier (many drugs
can pass)
Protein binding unbound drug is free which is active, crosses
membrane. Low plasma proteins result in more free
drug. Competition: when 2 highly bound drugs are
given it increases the level of both drugs
Metabolism take place in the liver mostly. Chemical change of a
drug structure to:
Enhance excretion, inactivate the drug, increase
therapeutic action, active a prodrug (inactive until
metabolized in the body into the active compound,
ex: levodopa), increase or decrease toxicity
CYP450 enzymes constitutes the most important of the
phase I metabolizing enzymes (account for about
75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to
large increases in hydrophilicity of the substrates
rendering them more readily excretable
Substrate an agent that is metabolized by an enzyme into a
metabolite and product and eventually excreted
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, 3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
Inhibitors compete with other drugs for a particular enzyme
affecting the metabolism (decreased) of the
substrate and decreases the excretion of the
substrate and increasing the circulating drug
inducer competes with other drugs for a particular enzyme
affecting metabolism of the substrate (increases)
decreasing the efficacy of the drug
excretion renal: passive glomerular filtration, active tubular
secretion, tubular reabsorption, gi tract, lung,
sweat and salivary, mammary
genomics study of the complete set of genetic information
present in a cell, an organism, or species
pharmacogenetics the study of the influence of hereditary factors on
the response of individual organisms to drugs, and
the study of variations of DNA and RNA
characteristics as related to drug response
Pharmacogenetics tests Mentioned on drug labels can be classified as "test
required," "test recommended," and "information
only." Currently, four drugs are required to have
pharmacogenetics testing performed before they
are prescribed: cetuximab, trastuzumab, maraviroc
and dasatinib
wafarin, carbamazepine, valproic acid and abacavir
are recommended to tests prior to initial dosing
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N5334 Final Exam Questions & Answers Test
QUESTIONS AND VERIFIED SOLUTIONS |2026|
ELABORATED &DETAILED ANSWERS!!
Save
Terms in this set (323)
Prescribing basics Prescribing is regulated by state BON
Proper RX Providers name and address, Telephone
DEA
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with
indication/Route and frequency, Quantity and
signature.
Drug Schedules: Most addictive to 1: Heroin,LSD, MJ
least 2: hydrocodone, cocaine, Methamphetamine,
methadone, oxycodone, meperidine, fentanyl,
adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics The effects of drug on the body. Receptors are
large molecules usually proteins, that interact and
mediate the action of drugs
https://quizlet.com/1161075278/n5334-final-exam-questions-answers-test-questions-and-verified-solutions-2026-elaborated-detailed-answers-flash-c… 1/46
,3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
agonist produce receptor stimulation and a conformational
change every time they bind. Do not need all
available receptors to produce a maximum
response
Partial agonist drugs that have properties in b/w those of full
agonist and antagonist. They bind to receptors but
when they occupy the receptor sites, they stimulate
only some of the receptors.
antagonist drugs with affinity for a receptor but with no
intrinsic activity. Affinity allows the antagonist to
bind to receptors, but lack of intrinsic activity
prevents the bound antagonist from causing
receptor activation. The block action of drugs (ex.
Narcan)
Bioavailabity % of administered dosage of the drug that survives
the first pass through the liver and reaches the
blood stream
half life Time required for the amount of a drug in the body
to decline by 50%, drugs with shorter half lives
must be administer frequently. 4.5-5.5 times the half
life to get steady state and to be limited from the
body
what the body does to the drug absorption, distribution, metabolism, excretion
https://quizlet.com/1161075278/n5334-final-exam-questions-answers-test-questions-and-verified-solutions-2026-elaborated-detailed-answers-flash-c… 2/46
,3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
Distribution movement of absorbed drug in bodily fluids
throughout the body to target tissue. Properties
affecting: lipid/water solubility, PH affects
ionization of drug, protein binding, size of
molecule (smaller molecules are more able to
diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid
soluble will pass), placental barrier (many drugs
can pass)
Protein binding unbound drug is free which is active, crosses
membrane. Low plasma proteins result in more free
drug. Competition: when 2 highly bound drugs are
given it increases the level of both drugs
Metabolism take place in the liver mostly. Chemical change of a
drug structure to:
Enhance excretion, inactivate the drug, increase
therapeutic action, active a prodrug (inactive until
metabolized in the body into the active compound,
ex: levodopa), increase or decrease toxicity
CYP450 enzymes constitutes the most important of the
phase I metabolizing enzymes (account for about
75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to
large increases in hydrophilicity of the substrates
rendering them more readily excretable
Substrate an agent that is metabolized by an enzyme into a
metabolite and product and eventually excreted
https://quizlet.com/1161075278/n5334-final-exam-questions-answers-test-questions-and-verified-solutions-2026-elaborated-detailed-answers-flash-c… 3/46
, 3/27/26, 8:59 AM N5334 Final Exam Questions & Answers Test QUESTIONS AND VERIFIED SOLUTIONS |2026| ELABORATED &DETAILED ANS…
Inhibitors compete with other drugs for a particular enzyme
affecting the metabolism (decreased) of the
substrate and decreases the excretion of the
substrate and increasing the circulating drug
inducer competes with other drugs for a particular enzyme
affecting metabolism of the substrate (increases)
decreasing the efficacy of the drug
excretion renal: passive glomerular filtration, active tubular
secretion, tubular reabsorption, gi tract, lung,
sweat and salivary, mammary
genomics study of the complete set of genetic information
present in a cell, an organism, or species
pharmacogenetics the study of the influence of hereditary factors on
the response of individual organisms to drugs, and
the study of variations of DNA and RNA
characteristics as related to drug response
Pharmacogenetics tests Mentioned on drug labels can be classified as "test
required," "test recommended," and "information
only." Currently, four drugs are required to have
pharmacogenetics testing performed before they
are prescribed: cetuximab, trastuzumab, maraviroc
and dasatinib
wafarin, carbamazepine, valproic acid and abacavir
are recommended to tests prior to initial dosing
https://quizlet.com/1161075278/n5334-final-exam-questions-answers-test-questions-and-verified-solutions-2026-elaborated-detailed-answers-flash-c… 4/46
