Systemic Lupus Erythematosus ( SLE )
Practice Questions and Answers (Top
Grade Assured) 2026 Update
A nurse is educating a patient diagnosed with Systemic Lupus
Erythematosus (SLE) about potential triggers. Which of the
following statements by the patient indicates a need for
further education?
A."I should avoid cigarette smoke as it can trigger my lupus
symptoms."
B."Physical stress, such as surgery or pregnancy, may worsen
my lupus."
C."Ultraviolet rays from the sun will help improve my lupus
symptoms."
D."I need to avoid medications like hydralazine and
minocycline, as they can worsen lupus." - Correct Answers
✅C. "Ultraviolet rays from the sun will help improve my lupus
symptoms."
Rationale: Ultraviolet (UV) rays from sunlight and fluorescent
lights can trigger lupus symptoms. Patients with lupus should
avoid excessive sun exposure.
A patient with SLE presents with hair loss and a butterfly-
shaped rash across their face. What other central nervous
system (CNS) symptom might the nurse assess for?
A.Myalgia
,Systemic Lupus Erythematosus ( SLE )
Practice Questions and Answers (Top
Grade Assured) 2026 Update
B.Cognitive difficulties
C.Fingertip lesions
D.Splenomegaly - Correct Answers ✅B. Cognitive
difficulties
Rationale: SLE can affect the central nervous system, causing
symptoms like headaches, dizziness, and cognitive
difficulties.
A patient with SLE reports having oral ulcers and difficulty
breathing. What condition should the nurse assess for that
might be affecting the patient's chest?
A.Pleuritis
B.Nephritis
C.Polyarthritis
D.Alopecia - Correct Answers ✅A. Pleuritis
Rationale: Pleuritis is inflammation of the lining of the lungs
(pleura), which can cause difficulty breathing and chest pain
in patients with SLE.
, Systemic Lupus Erythematosus ( SLE )
Practice Questions and Answers (Top
Grade Assured) 2026 Update
A nurse is assessing a patient with SLE who is complaining of
joint pain and stiffness. Which of the following manifestations
is most likely associated with the patient's complaint?
A.Polyarthritis
B.Lupus glomerulonephritis
C.Pericarditis
D.CNS symptoms - Correct Answers ✅A. Polyarthritis
Rationale: Polyarthritis, or inflammation of multiple joints, is
common in patients with SLE and causes pain and stiffness in
the joints.
Which of the following blood disorders is most commonly
associated with Systemic Lupus Erythematosus (SLE)?
A.Anemia, neutropenia, thrombocytopenia
B.Leukocytosis, thrombocytosis, polycythemia
C.Hemophilia, neutrophilia, eosinophilia
D.Hyperkalemia, hypernatremia, hypercalcemia - Correct
Answers ✅A. Anemia, neutropenia, thrombocytopenia
Rationale: SLE can cause low levels of red blood cells
(anemia), white blood cells (neutropenia), and platelets
Practice Questions and Answers (Top
Grade Assured) 2026 Update
A nurse is educating a patient diagnosed with Systemic Lupus
Erythematosus (SLE) about potential triggers. Which of the
following statements by the patient indicates a need for
further education?
A."I should avoid cigarette smoke as it can trigger my lupus
symptoms."
B."Physical stress, such as surgery or pregnancy, may worsen
my lupus."
C."Ultraviolet rays from the sun will help improve my lupus
symptoms."
D."I need to avoid medications like hydralazine and
minocycline, as they can worsen lupus." - Correct Answers
✅C. "Ultraviolet rays from the sun will help improve my lupus
symptoms."
Rationale: Ultraviolet (UV) rays from sunlight and fluorescent
lights can trigger lupus symptoms. Patients with lupus should
avoid excessive sun exposure.
A patient with SLE presents with hair loss and a butterfly-
shaped rash across their face. What other central nervous
system (CNS) symptom might the nurse assess for?
A.Myalgia
,Systemic Lupus Erythematosus ( SLE )
Practice Questions and Answers (Top
Grade Assured) 2026 Update
B.Cognitive difficulties
C.Fingertip lesions
D.Splenomegaly - Correct Answers ✅B. Cognitive
difficulties
Rationale: SLE can affect the central nervous system, causing
symptoms like headaches, dizziness, and cognitive
difficulties.
A patient with SLE reports having oral ulcers and difficulty
breathing. What condition should the nurse assess for that
might be affecting the patient's chest?
A.Pleuritis
B.Nephritis
C.Polyarthritis
D.Alopecia - Correct Answers ✅A. Pleuritis
Rationale: Pleuritis is inflammation of the lining of the lungs
(pleura), which can cause difficulty breathing and chest pain
in patients with SLE.
, Systemic Lupus Erythematosus ( SLE )
Practice Questions and Answers (Top
Grade Assured) 2026 Update
A nurse is assessing a patient with SLE who is complaining of
joint pain and stiffness. Which of the following manifestations
is most likely associated with the patient's complaint?
A.Polyarthritis
B.Lupus glomerulonephritis
C.Pericarditis
D.CNS symptoms - Correct Answers ✅A. Polyarthritis
Rationale: Polyarthritis, or inflammation of multiple joints, is
common in patients with SLE and causes pain and stiffness in
the joints.
Which of the following blood disorders is most commonly
associated with Systemic Lupus Erythematosus (SLE)?
A.Anemia, neutropenia, thrombocytopenia
B.Leukocytosis, thrombocytosis, polycythemia
C.Hemophilia, neutrophilia, eosinophilia
D.Hyperkalemia, hypernatremia, hypercalcemia - Correct
Answers ✅A. Anemia, neutropenia, thrombocytopenia
Rationale: SLE can cause low levels of red blood cells
(anemia), white blood cells (neutropenia), and platelets
