Questions and Answers (Top Grade
Assured) 2026 Update
Systemic Lupus Erythematosus - Correct Answers ✅SLE is
a chronic inflammatory immune disorder affecting the skin
and other body organs. Antibodies to DNA and RNA cause an
autoimmune inflammatory response, resulting in swelling and
pain. It is most common in young women, and has a strong
genetic factor. The etiology is not known
SLE characterized by periods of - Correct Answers
✅remission and exacerbation
autoantibody production results from - Correct Answers
✅hyperreactivity of B cells(humoral immune response)
SLE autoantibodies react with their corresponding antigen to
form immune complexes, which are then deposited in the: -
Correct Answers ✅connective tissues of blood vessels,
lymphatic vessels, and other tissues
frequent site of complex deposition and damage occur in the
- Correct Answers ✅kidneys
Systemic Lupus - Correct Answers ✅Systemic lupus is the
most common form of lupus, and is what most people mean
when they refer to "lupus." Systemic lupus can be mild or
severe. Some of the more serious complications involving
major organ systems are:
,Systemic Lupus Erythematosus
Questions and Answers (Top Grade
Assured) 2026 Update
inflammation of the kidneys (lupus nephritis), which can
affect the body's ability to filter waste from the blood and can
be so damaging that dialysis or kidney transplant may be
needed
an increase in blood pressure in the lungs (pulmonary
hypertension)
inflammation of the nervous system and brain, which can
cause memory problems, confusion, headaches, and strokes
SLE Triggers - Correct Answers ✅While a person's genes
may increase the chance that he or she will develop lupus, it
takes some kind of environmental trigger to set off the illness
or to bring on a flare. Examples include:
• ultraviolet rays from the sun
• ultraviolet rays from fluorescent light bulbs
• sulfa drugs, which make a person more sensitive to the sun,
such as: Bactrim® and Septra® (trimethoprim-
sulfamethoxazole); sulfisoxazole (Gantrisin®); tolbutamide
(Orinase®); sulfasalazine (Azulfidine®); diuretics
• sun-sensitizing tetracycline drugs such as minocycline
(Minocin®)
• penicillin or other antibiotic drugs such as: amoxicillin
(Amoxil®); ampicillin (Ampicillin Sodium ADD-Vantage®);
cloxacillin (Cloxapen®)
• an infection
, Systemic Lupus Erythematosus
Questions and Answers (Top Grade
Assured) 2026 Update
• a cold or a viral illness
• exhaustion
• an injury
• emotional stress, such as a divorce, illness, death in the
family, or other life complications
• anything that causes stress to the body, such as surgery,
physical harm, pregnancy, or giving birth
Although many seemingly unrelated factors can trigger the
onset of lupus in a susceptible person, scientists have noted
some common features among many people who have lupus,
including:
• exposure to the sun
• an infection
• being pregnant
• giving birth
• a drug taken to treat an illness
Clients with active disease have an increased risk for -
Correct Answers ✅infections
Early manifestations include - Correct Answers ✅Because
lupus can affect so many different organs, a wide range of
symptoms can occur. These symptoms may come and go,
and different symptoms may appear at different times during
the course of the disease.