COMSAE PHASE 2 FORM 110
COMSAE PHASE 2 FORM 110 REVIEW EXAM QUESTIONS AND 100% CORRECT
ANSWERS 2026/27 UPDATE
1.
A 56-year-old man presents with substernal chest pain that began 1 hour ago while he was
mowing the lawn. The pain is pressure-like and radiates to the left arm. ECG shows ST elevation
in leads II, III, and aVF. Next best step in management?
A. Give sublingual nitroglycerin
B. Administer aspirin and activate cardiac catheterization lab
C. Start IV heparin only
D. Order a chest X-ray
ANS: B. Administer aspirin and activate cardiac catheterization lab
ST elevation in II, III, aVF = inferior STEMI. Reperfusion therapy is required (PCI if available).
Aspirin reduces mortality. Chest X-ray is not appropriate initially, and nitro is supportive but
not definitive.
2.
A 25-year-old woman presents with fever, dysuria, and flank pain. Urinalysis shows WBC casts.
Best treatment?
A. Oral nitrofurantoin
B. IV ceftriaxone
C. Oral ciprofloxacin
D. IV vancomycin
,COMSAE PHASE 2 FORM 110
ANS: B. IV ceftriaxone
WBC casts indicate pyelonephritis. Inpatient IV therapy (ceftriaxone) is indicated for systemic
symptoms. Nitrofurantoin is for simple cystitis, not pyelo.
3.
A 60-year-old man with chronic alcohol use presents with confusion, ataxia, and
ophthalmoplegia. Which vitamin deficiency is most likely?
A. Vitamin B1 (thiamine)
B. Vitamin B6 (pyridoxine)
C. Vitamin B12 (cobalamin)
D. Vitamin C
ANS: A. Vitamin B1 (thiamine)
Classic Wernicke encephalopathy triad: confusion, ataxia, ophthalmoplegia →
thiamine deficiency.
4.
A 32-year-old woman presents with fatigue, weight gain, constipation, and dry skin. TSH is
elevated. Best treatment?
A. Methimazole
B. Levothyroxine
C. Radioactive iodine
D. Propranolol
ANS: B. Levothyroxine
Primary hypothyroidism (high TSH). Levothyroxine is standard treatment.
5.
,COMSAE PHASE 2 FORM 110
A 7-year-old boy has a sore throat, fever, and sandpaper-like rash. Rapid strep antigen test is
positive. Best treatment?
A. Amoxicillin
B. Azithromycin
C. Ciprofloxacin
D. Supportive care only
ANS: A. Amoxicillin
Scarlet fever is caused by Group A strep. Treat with penicillin or amoxicillin.
6.
A 19-year-old male presents after a motorcycle accident. He is hypotensive, has distended
neck veins, and tracheal deviation to the left. Best initial management?
A. Endotracheal intubation
B. Needle thoracostomy
C. Chest tube placement
D. IV fluids
ANS: B. Needle thoracostomy
Tension pneumothorax → immediate decompression with needle thoracostomy,
followed by chest tube.
7.
A 72-year-old man has a resting tremor, bradykinesia, and cogwheel rigidity. Most appropriate
initial therapy?
A. Levodopa-carbidopa
B. Bromocriptine
C. Selegiline
, COMSAE PHASE 2 FORM 110
D. Amantadine
ANS: A. Levodopa-carbidopa
Parkinson’s first-line therapy in elderly is levodopa-carbidopa. Dopamine agonists are more
often used in younger patients.
8.
A 22-year-old woman presents with RLQ abdominal pain, fever, and leukocytosis. What is the
most likely diagnosis?
A. Ectopic pregnancy
B. Appendicitis
C. Ovarian torsion
D. Pelvic inflammatory disease
ANS: B. Appendicitis
Classic presentation of appendicitis in a young adult with RLQ pain and leukocytosis.
9.
A 3-year-old girl presents with a barking cough, stridor, and hoarseness. Symptoms worsen at
night. Best initial management?
A. Racemic epinephrine
B. IV dexamethasone
C. Humidified air and corticosteroids
D. Intubation
ANS: C. Humidified air and corticosteroids
Croup (parainfluenza). Mild-moderate cases managed with humidified air + corticosteroids.
Racemic epi for severe cases.
COMSAE PHASE 2 FORM 110 REVIEW EXAM QUESTIONS AND 100% CORRECT
ANSWERS 2026/27 UPDATE
1.
A 56-year-old man presents with substernal chest pain that began 1 hour ago while he was
mowing the lawn. The pain is pressure-like and radiates to the left arm. ECG shows ST elevation
in leads II, III, and aVF. Next best step in management?
A. Give sublingual nitroglycerin
B. Administer aspirin and activate cardiac catheterization lab
C. Start IV heparin only
D. Order a chest X-ray
ANS: B. Administer aspirin and activate cardiac catheterization lab
ST elevation in II, III, aVF = inferior STEMI. Reperfusion therapy is required (PCI if available).
Aspirin reduces mortality. Chest X-ray is not appropriate initially, and nitro is supportive but
not definitive.
2.
A 25-year-old woman presents with fever, dysuria, and flank pain. Urinalysis shows WBC casts.
Best treatment?
A. Oral nitrofurantoin
B. IV ceftriaxone
C. Oral ciprofloxacin
D. IV vancomycin
,COMSAE PHASE 2 FORM 110
ANS: B. IV ceftriaxone
WBC casts indicate pyelonephritis. Inpatient IV therapy (ceftriaxone) is indicated for systemic
symptoms. Nitrofurantoin is for simple cystitis, not pyelo.
3.
A 60-year-old man with chronic alcohol use presents with confusion, ataxia, and
ophthalmoplegia. Which vitamin deficiency is most likely?
A. Vitamin B1 (thiamine)
B. Vitamin B6 (pyridoxine)
C. Vitamin B12 (cobalamin)
D. Vitamin C
ANS: A. Vitamin B1 (thiamine)
Classic Wernicke encephalopathy triad: confusion, ataxia, ophthalmoplegia →
thiamine deficiency.
4.
A 32-year-old woman presents with fatigue, weight gain, constipation, and dry skin. TSH is
elevated. Best treatment?
A. Methimazole
B. Levothyroxine
C. Radioactive iodine
D. Propranolol
ANS: B. Levothyroxine
Primary hypothyroidism (high TSH). Levothyroxine is standard treatment.
5.
,COMSAE PHASE 2 FORM 110
A 7-year-old boy has a sore throat, fever, and sandpaper-like rash. Rapid strep antigen test is
positive. Best treatment?
A. Amoxicillin
B. Azithromycin
C. Ciprofloxacin
D. Supportive care only
ANS: A. Amoxicillin
Scarlet fever is caused by Group A strep. Treat with penicillin or amoxicillin.
6.
A 19-year-old male presents after a motorcycle accident. He is hypotensive, has distended
neck veins, and tracheal deviation to the left. Best initial management?
A. Endotracheal intubation
B. Needle thoracostomy
C. Chest tube placement
D. IV fluids
ANS: B. Needle thoracostomy
Tension pneumothorax → immediate decompression with needle thoracostomy,
followed by chest tube.
7.
A 72-year-old man has a resting tremor, bradykinesia, and cogwheel rigidity. Most appropriate
initial therapy?
A. Levodopa-carbidopa
B. Bromocriptine
C. Selegiline
, COMSAE PHASE 2 FORM 110
D. Amantadine
ANS: A. Levodopa-carbidopa
Parkinson’s first-line therapy in elderly is levodopa-carbidopa. Dopamine agonists are more
often used in younger patients.
8.
A 22-year-old woman presents with RLQ abdominal pain, fever, and leukocytosis. What is the
most likely diagnosis?
A. Ectopic pregnancy
B. Appendicitis
C. Ovarian torsion
D. Pelvic inflammatory disease
ANS: B. Appendicitis
Classic presentation of appendicitis in a young adult with RLQ pain and leukocytosis.
9.
A 3-year-old girl presents with a barking cough, stridor, and hoarseness. Symptoms worsen at
night. Best initial management?
A. Racemic epinephrine
B. IV dexamethasone
C. Humidified air and corticosteroids
D. Intubation
ANS: C. Humidified air and corticosteroids
Croup (parainfluenza). Mild-moderate cases managed with humidified air + corticosteroids.
Racemic epi for severe cases.