Psychopharmacology Review
EXAM MOST TESTED
QUESTIONS AND VERIFIED
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naltrexone class - 🧠 ANSWER ✔✔Opioid receptor antagonist
Naltrexone can be used for - 🧠 ANSWER ✔✔both ETOH and opioid use
disorders
,What does naltrexone do - 🧠 ANSWER ✔✔Reduces desire/cravings, First
line treatment, Will precipitate withdrawal in patients with physical opioid
dependence
First line treatment in maintaining abstinence after detox - 🧠 ANSWER
✔✔acamprosate
acamprosate can be used - 🧠 ANSWER ✔✔in liver disease- not
metabolized by the liver (not impacted by ETOH use). Can be administered
to patients with hepatitis, liver disease, and those who continue drinking
alcohol
acamprosate Contraindicated in - 🧠 ANSWER ✔✔severe renal disease
acamprosate helps with - 🧠 ANSWER ✔✔Decreasing cravings
ETOH 2nd line treatment - 🧠 ANSWER ✔✔disulfiram (Antabuse)
disulfiram (Antabuse) causes - 🧠 ANSWER ✔✔aversion reaction to ETOH
(flushing, headaches, n/v, palpitation, SOB, vertigo, hypotension)
disulfiram (Antabuse) Do not - 🧠 ANSWER ✔✔administer until the person
has been alcohol free at least 12 hours
, disulfiram (Antabuse) MOA - 🧠 ANSWER ✔✔Blocks enzyme (aldehyde
dehydrogenase) in the liver
ETOH withdrawal- Benzos - 🧠 ANSWER ✔✔To keep patient calm and
lightly sedated
Benzos MOA - 🧠 ANSWER ✔✔Enhance the effects of GABA
Meds used in mild alcohol withdrawal - 🧠 ANSWER ✔✔Tegretol, Valproic
or Gabapentin
ETHO meds for nutritional deficiencies - 🧠 ANSWER ✔✔Thiamine, folic
acid, and multivitamin - 'Banana bag'
Wernicke's encephalopathy treatment - 🧠 ANSWER ✔✔Parenteral
Thiamine and Folate
Wernicke's encephalopathy cause - 🧠 ANSWER ✔✔B1 deficiency
Cocaine mechanism - 🧠 ANSWER ✔✔reuptake of dopamine, epinephrine,
and NE = Stimulant effect
Cocaine effects on the body - 🧠 ANSWER ✔✔has vasoconstrictive effects =
can cause MI, stroke
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