Jean Genzale 2026 Exam
Questions and Answers | 100%
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1. A 42 y / o woman is diagnosed with bacteremia in the ED . The NP
empirically starts antibiotics and want the first dose of Vancomycin to be
given prior to admission to the floor . The hospital has a vancomycin
nomogram for 15 mg / kg initial dosing ( rounded to the nearest 250 mg ) ,
followed by pharmacy dosing / pharmacokinetic service . If the patient
,weighs 154 pounds , what dose of vancomycin would the patient receive in
the ED ? Please give your answer as a whole number without units . -
🧠ANSWER ✔✔1000
The study of pharmacodynamics involves all of the following EXCEPT ,
CHOOSE ONE ANSWER
a . Biological effects of drugs 20 1919
b . Biotransformation of drugs
c . Chemical alteration of the cellular environment
d . Mechanism of a drug's action - 🧠ANSWER ✔✔b . Biotransformation of
drugs
3. In regard to pharmacodynamics , " affinity " can be defined as :
CHOOSE ONE ANSWER
a . The measure of how tightly a drug binds to plasma proteins
b . The amount of time that a measurable drug effect persists
c . The degree of attraction between a drug and its receptor
d . The measure of a drug's bioavailability - 🧠ANSWER ✔✔c . The degree
of attraction between a drug and its receptor
,4. Antagonist drugs prevent the actions of the body's endogenous
biomediators on their receptors by which mechanism ? CHOOSE ONE
ANSWER
a . Preventing agonist drugs from binding to antagonist drug
b . Binding to the receptor and activating it
c . Preventing occupancy of the receptor
d . Mimicking the actions of the body's endogenous biomediators -
🧠ANSWER ✔✔c . Preventing occupancy of the receptor
What are the two most important sites for drug elimination ? CHOOSE
ONE ANSWER
a . liver and gastrointestinal tract
b . kidneys and liver
c . lungs and liver
d . skin and kidneys - 🧠ANSWER ✔✔b . kidneys and liver
ALSY 6. Acetaminophen and codeine are given together for pain relief .
The drug - drug interaction is : CHOOSE ONE ANSWER
a . Beneficial inhibitory
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, b . Beneficial potentiative
c . Harmful inhibitory
d . Harmful potentiative - 🧠ANSWER ✔✔b . Beneficial potentiative
Drugs that are receptor agonists may demonstrate what property ?
CHOOSE ONE ANSWER
a . Irreversible binding to the drug receptor site
b . Desensitization or down regulation with continuous use
c . Inverse relationship between drug concentration and drug action
d . Up - regulation with chronic use - 🧠ANSWER ✔✔b . Desensitization or
down regulation with continuous use
8. Which of the following is an example of a graded drug response ?
CHOOSE ONE ANSWER
a . Blood pressure
b . Death
c . Rash
d . Sleep - 🧠ANSWER ✔✔a . Blood pressure