i-Human Case Study 2025/2026: Confusion & Memory Loss in a 79-Year-Old – Alzheimer’s Disease Evaluation & Management

A comprehensive i-Human case study for 2025/2026 on a 79-year-old female presenting with progressive confusion, memory loss, and unintentional weight loss over two to three years. This case explores the systematic evaluation of major neurocognitive disorder (Alzheimer's disease) in a geriatric patient, including collateral history collection, cognitive domain assessment using standardized tools (MMSE/MoCA), differential diagnosis (Alzheimer's vs. Lewy body dementia vs. mixed dementia vs. reversible causes), diagnostic testing (thyroid, B12, folate, neuroimaging), and evidence-based management with cholinesterase inhibitors, non-pharmacological interventions, caregiver support, and advance care planning. Ideal for advanced practice nursing, medical students, and primary care clinicians preparing for i-Human simulations, NRNP coursework, and geriatric clinical rotations.