NU 578
NU 578 Unit 2 Exam| Questions and Answers
|with Detailed Rationales| 2026 Graded A+
1.
Pharmacokinetics refers to:
A. Drug effects on receptors
B. Movement of drugs through the body
C. Drug classification
D. Drug cost
Rationale:
Pharmacokinetics describes how the body handles a drug through absorption, distribution,
metabolism, and excretion (ADME).
2.
Which process involves drug entry into the bloodstream?
A. Distribution
B. Absorption
C. Metabolism
D. Excretion
Rationale:
Absorption is the movement of a drug from the site of administration into systemic circulation.
3.
The primary site of drug metabolism is the:
A. Kidney
B. Liver
C. Lung
D. Brain
Rationale:
The liver contains enzymes (CYP450) that metabolize most drugs.
NU 578
, NU 578
4.
Drug excretion mainly occurs through the:
A. Liver
B. Kidneys
C. Skin
D. Lungs
Rationale:
The kidneys eliminate drugs via filtration, secretion, and reabsorption.
5.
Which route avoids first-pass metabolism?
A. Oral
B. Intravenous
C. Rectal
D. Sublingual
Rationale:
IV administration delivers the drug directly into circulation, bypassing liver metabolism.
6.
Bioavailability refers to:
A. Drug metabolism rate
B. Amount of drug reaching circulation
C. Drug toxicity
D. Drug half-life
Rationale:
It measures how much of the administered drug reaches systemic circulation unchanged.
7.
First-pass effect occurs in the:
A. Kidneys
B. Liver
NU 578
NU 578 Unit 2 Exam| Questions and Answers
|with Detailed Rationales| 2026 Graded A+
1.
Pharmacokinetics refers to:
A. Drug effects on receptors
B. Movement of drugs through the body
C. Drug classification
D. Drug cost
Rationale:
Pharmacokinetics describes how the body handles a drug through absorption, distribution,
metabolism, and excretion (ADME).
2.
Which process involves drug entry into the bloodstream?
A. Distribution
B. Absorption
C. Metabolism
D. Excretion
Rationale:
Absorption is the movement of a drug from the site of administration into systemic circulation.
3.
The primary site of drug metabolism is the:
A. Kidney
B. Liver
C. Lung
D. Brain
Rationale:
The liver contains enzymes (CYP450) that metabolize most drugs.
NU 578
, NU 578
4.
Drug excretion mainly occurs through the:
A. Liver
B. Kidneys
C. Skin
D. Lungs
Rationale:
The kidneys eliminate drugs via filtration, secretion, and reabsorption.
5.
Which route avoids first-pass metabolism?
A. Oral
B. Intravenous
C. Rectal
D. Sublingual
Rationale:
IV administration delivers the drug directly into circulation, bypassing liver metabolism.
6.
Bioavailability refers to:
A. Drug metabolism rate
B. Amount of drug reaching circulation
C. Drug toxicity
D. Drug half-life
Rationale:
It measures how much of the administered drug reaches systemic circulation unchanged.
7.
First-pass effect occurs in the:
A. Kidneys
B. Liver
NU 578
