Understanding Pathophysiology 7th
Edition
by Sue E. Huether & Kathryn L. McCance
7TH EDITION
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, Chapter 01: Cellular Biology
Huether & McCance: Understanding Pathophysiology, 7th Edition
MULTIPLE CHOICE
1. A student is observing a cell under the microscope. It is observed to
have supercoiled DNA with histones. Which of the following would
also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles
ANS: B
The cell described is a eukaryotic cell, so it has histones and a
supercoiled DNA within its nucleus; thus, the nucleus should be
observed. A single circular chromosome called a prokaryote contains
free-floating nuclear material but has no organelles.
REF: p. 2
2. A nurse is instructing the staff about cellular functions. Which cellular
function is the nurse describing when an isolated cell absorbs oxygen
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and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration
ANS: D
The cell’s ability to absorb oxygen is referred to as respiration while its
communication ability involves maintenance of a steady dynamic state,
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metabolic absorption provides nutrition, and secretion allows for the
synthesizing of new substances.
REF: p. 2
3. A eukaryotic cell is undergoing DNA replication. In which region of
the cell would most of the genetic information be contained?
a. Mitochondria
b. Ribosome
c. Nucleolus
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d. Nucleus Cytoplasm
ANS: C
The region of the cell that contains genetic material, including a large
amount of ribonucleic acid, most of the DNA, and DNA-binding
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,proteins, is the nucleolus, which is located within the cell’s nucleus.
Mitochondria is associated with cellular respiration, while ribosomes are
involved with protein manufacturing. Cytoplasm is a fluid filling that is
a component of the cell.
REF: p. 2
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, 4. Which of the following can remove proteins attached to the cell’s
bilayer by dissolving the layer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules
ANS: B
Proteins directly attached to the membrane bilayer can be removed by
the action of integral membrane proteins that dissolve the bilayer.
Peripheral membrane proteins reside at the surface while cell adhesion
molecules are on the outside of the membrane. Glycoprotein marks cells
and does not float.
REF: p. 7
5. Which of the following can bind to plasma membrane receptors?
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands
ANS: D
Ligands are the only specific molecules that can bind with receptors on the
cell membrane.
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REF: p. 9
6. A nurse is reviewing a report from a patient with metastatic cancer.
What alternation in the U extracellular
S N T matrix
O would s uNp p oRr t t hIe
dGiagnBo.siC
s ofMmetastatic cancer?
a. Decreased fibronectin
b. Increased collagen
c. Decreased elastin
d. Increased glycoproteins
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ANS: A
Only a reduced amount of fibronectin is found in some types of
cancerous cells, allowing them to travel or metastasize.
REF: p. 10
7. Which form of cell communication is used to relate to other cells in direct
physical contact?
a. Cell junction
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b. Gap junction
c. Desmosome
d. Tight junction
ANS: A
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