NU 578 Exam1| Actual Questions and Answers
Latest Updated (Graded A+)-USA
1. When stimulated, the function of the alpha-2 receptor is
E. to increase heart rate and force of contraction
B. to dilate smooth muscle of the airways
D. to cause mydriasis
C. to reduce further release of neurotransmitter*
2. To assess the renal function of 72- year old, the apn knows to check which lab value.
D. Creatinine*
3. Drugs that are subject to extensive first-pass metabolism:
a. May be administered rectally and completely escape first-pass metabolism*
b. Require larger intravenous doses than oral doses
c. Cannot be given orally
d. May be more efficacious given by a parenteral route.
4. A 29 year old with hx of upper abdominal pain and tarry stools to determine to have
peptic ulcer disease. Pharmacologic therapy includes an anticholinergic drug. Upon
taking his medication which of the following assessment findings would be most likely in
this client? Bradycardia, hyperactive bowel sounds, dilated pupils, tenesmus, drooling.*
5. Drug metabolizing enzymes may be found primarily in the? A. brain b. kidney c.
intestinal lining d. liver
6. With respect to drug metabolizing enzymes (DME). A. activity of drug metabolizing
enzymes in children does not really develop until one year of age b. activity of drug
metabolizing enzymes is the same in men and women for all drugs c P-Glycoprotein is
the main drug metabolizing enzymes in the liver d. these are found primarily in the gut
and kidneys. ?????
7. Termination of acetylcholine at the synaptic junction occur through degradation by.
Acetylcholinesterase
8. A patient is being evaluated in the emergency department with a differential diagnosis
of antimuscarinic poisoning versus psychosis. Which of the following signs and
symptoms will the nurse expect to see if the experiencing poison? A. hypothermia b.
cold, pale skin c. dry mouth d. salivation
9. Women who are prescribed a drug in category X must be counseled to, and at a
minimum: a. use reliable birth control b. not worry unless planning to conceive in the
near future c. only take the medication on days during which no intercourse takes place
d. refuse the med
, 10. The only reason that a patient would be taking a irreversible cholinesterase inhibitor
would be for the treatment of: Myasthenia gravis
11. Which of the following patients would not be a candidate to receive a beta-1 agonist? A.
patient in shock b. patient in heart failure c. patient in cardiac arrest d. patient with
chest pain
12. A patient is taking pseudoephedrine (Sudafed) for congestion due to seasonal allergies.
The practitioner would expect to find which of the following in this patient? A, increased
bp due to an effect on alpha 1 receptors b. increased bladder contractions due to an
effect on muscarine receptors c. decreased blood flow to the kidneys via an effect on
dopamine receptors d. increased respiratory tone due to an effect on beta 2 receptors
13. A consideration of the use of Tolterodine includes: a. recognizing that it is ineffective
against urge incontinence b. understanding that dry mouth and constipation are minimal
side effects with this drug c. knowing that it will interact with other drugs metabolized
by CyP34S4 d. knowing that the patient may take up to 8 mg/ day if needed for a
therapeutic response
14. When a pregnant woman takes a drug that results in the infant having a birth defect, the
effect is called: Teratogenic
15. If a patient with hypoalbuminemia is prescribed a drug that is normally extensively
protein bound, both the patient and caregiver need to be aware of: a. longer half-life of
the drug b. potentially greater incidence of adverse drug effects or toxicity c. a further
lowering of plasma proteins d. delayed or absent therapeutic effects
16. The nurse practitioner caring for a patient who was exposed to tuberculosis and who
must undergo prophalaxis with isoniazid, a known inhibitor of CYP isoenzymes. The
patient is on several other medications for comorbid conditions. The Nurse knows he
will have to? A. make no adjustment to the med regimen b. monitor for lack of efficacy
of the other meds and increase the dosage accordingly c. monitor for potential toxicity
of the other medications and adjust dosages d. discontinue all meds while on the
isoniazid
17. A patient previously on propranolol for HTN is to stop the drug as his Blood pressure has
returned to normal for the past 3 months with lifestyle changes. The nurse would advise:
taper the drug over 2 weeks period to prevent complications.
18. Beta 2 selective agonists like albuterol have their greatest utility in the treatment of: a.
Asthma
Latest Updated (Graded A+)-USA
1. When stimulated, the function of the alpha-2 receptor is
E. to increase heart rate and force of contraction
B. to dilate smooth muscle of the airways
D. to cause mydriasis
C. to reduce further release of neurotransmitter*
2. To assess the renal function of 72- year old, the apn knows to check which lab value.
D. Creatinine*
3. Drugs that are subject to extensive first-pass metabolism:
a. May be administered rectally and completely escape first-pass metabolism*
b. Require larger intravenous doses than oral doses
c. Cannot be given orally
d. May be more efficacious given by a parenteral route.
4. A 29 year old with hx of upper abdominal pain and tarry stools to determine to have
peptic ulcer disease. Pharmacologic therapy includes an anticholinergic drug. Upon
taking his medication which of the following assessment findings would be most likely in
this client? Bradycardia, hyperactive bowel sounds, dilated pupils, tenesmus, drooling.*
5. Drug metabolizing enzymes may be found primarily in the? A. brain b. kidney c.
intestinal lining d. liver
6. With respect to drug metabolizing enzymes (DME). A. activity of drug metabolizing
enzymes in children does not really develop until one year of age b. activity of drug
metabolizing enzymes is the same in men and women for all drugs c P-Glycoprotein is
the main drug metabolizing enzymes in the liver d. these are found primarily in the gut
and kidneys. ?????
7. Termination of acetylcholine at the synaptic junction occur through degradation by.
Acetylcholinesterase
8. A patient is being evaluated in the emergency department with a differential diagnosis
of antimuscarinic poisoning versus psychosis. Which of the following signs and
symptoms will the nurse expect to see if the experiencing poison? A. hypothermia b.
cold, pale skin c. dry mouth d. salivation
9. Women who are prescribed a drug in category X must be counseled to, and at a
minimum: a. use reliable birth control b. not worry unless planning to conceive in the
near future c. only take the medication on days during which no intercourse takes place
d. refuse the med
, 10. The only reason that a patient would be taking a irreversible cholinesterase inhibitor
would be for the treatment of: Myasthenia gravis
11. Which of the following patients would not be a candidate to receive a beta-1 agonist? A.
patient in shock b. patient in heart failure c. patient in cardiac arrest d. patient with
chest pain
12. A patient is taking pseudoephedrine (Sudafed) for congestion due to seasonal allergies.
The practitioner would expect to find which of the following in this patient? A, increased
bp due to an effect on alpha 1 receptors b. increased bladder contractions due to an
effect on muscarine receptors c. decreased blood flow to the kidneys via an effect on
dopamine receptors d. increased respiratory tone due to an effect on beta 2 receptors
13. A consideration of the use of Tolterodine includes: a. recognizing that it is ineffective
against urge incontinence b. understanding that dry mouth and constipation are minimal
side effects with this drug c. knowing that it will interact with other drugs metabolized
by CyP34S4 d. knowing that the patient may take up to 8 mg/ day if needed for a
therapeutic response
14. When a pregnant woman takes a drug that results in the infant having a birth defect, the
effect is called: Teratogenic
15. If a patient with hypoalbuminemia is prescribed a drug that is normally extensively
protein bound, both the patient and caregiver need to be aware of: a. longer half-life of
the drug b. potentially greater incidence of adverse drug effects or toxicity c. a further
lowering of plasma proteins d. delayed or absent therapeutic effects
16. The nurse practitioner caring for a patient who was exposed to tuberculosis and who
must undergo prophalaxis with isoniazid, a known inhibitor of CYP isoenzymes. The
patient is on several other medications for comorbid conditions. The Nurse knows he
will have to? A. make no adjustment to the med regimen b. monitor for lack of efficacy
of the other meds and increase the dosage accordingly c. monitor for potential toxicity
of the other medications and adjust dosages d. discontinue all meds while on the
isoniazid
17. A patient previously on propranolol for HTN is to stop the drug as his Blood pressure has
returned to normal for the past 3 months with lifestyle changes. The nurse would advise:
taper the drug over 2 weeks period to prevent complications.
18. Beta 2 selective agonists like albuterol have their greatest utility in the treatment of: a.
Asthma
