6TH YEAR STATE EXAM WRITTEN STATE-
NEUROLOGY_NEUROMUSCULAR DISEASES
• 1
NEU - 6.1
Which symptom is not characteristic for Myasthenia
gravis?
A) diplopia
B) ptosis
C) dysarthria
D) aphasia
E) muscle weakness worsening with physical exercise
D) aphasia
Aphasia: disturbance of higher integral process of the brain due
to the damage of certain cortical areas and connecting
pathways. It is not the symptom of myasthenia gravis (MG).
• 2
NEU - 6.2
First-choice treatment in Myasthenia gravis:
A) atropin
B) acetylcholinesterase inhibitors
C) steroid
,D) plasma exchange therapy
E) vitamins
B) acetylcholinesterase inhibitors
Acetylcholinesterase inhibitors: Myasthenia gravis is caused by
the disturbance of neuromuscular transmission due to the
damage to the postsynaptic membrane function triggered by the
anti-ACh-receptor antibody.
• 3
NEU - 6.3
Motor neurone disease:
A) Eaton–Lambert syndrome
B) Amyotrophic lateral sclerosis
C) Duchenne muscular dystrophy
D) Guillain–Barré syndrome
B) Amyotrophic lateral sclerosis
Eaton-Lambert-syndrome is the disease of the presynaptic
neuromuscular transmission (usually caused by anti-calcium
channel antibodies of paraneoplastic origin) Amyotrophic lateral
sclerosis: signs of both upper and lower motor neuron lesion
can be observed Duchenne disease: X-linked muscular
dystrophy of recessive inheritance Guillain-Barré-syndrome:
, inflammatory, immune-mediated polyganglioradiculitis with
segmental demyelinisation.
• 4
NEU - 6.4
Which symptom is not characteristic for Amyotrophic
lateral sclerosis?
A) Babinski-reflex (extensor plantar reflex)
B) atrophy of the small hand muscles
C) fasciculation
D) dysphagia
E) paraesthesia
E) paraesthesia
Paraesthesia: not a sign of ALS. Sensory system is not affected
in this disease. ALS is a disease of both the lower and upper
motor neurons (with the degeneration of the corticospinal tract).
• 5
NEU - 6.5
Which is not characteristic for Guillain–Barré syndrome?
A) albuminocytologic dissociation in the CSF
B) ascending paresis
C) cranial nerves are never affected
NEUROLOGY_NEUROMUSCULAR DISEASES
• 1
NEU - 6.1
Which symptom is not characteristic for Myasthenia
gravis?
A) diplopia
B) ptosis
C) dysarthria
D) aphasia
E) muscle weakness worsening with physical exercise
D) aphasia
Aphasia: disturbance of higher integral process of the brain due
to the damage of certain cortical areas and connecting
pathways. It is not the symptom of myasthenia gravis (MG).
• 2
NEU - 6.2
First-choice treatment in Myasthenia gravis:
A) atropin
B) acetylcholinesterase inhibitors
C) steroid
,D) plasma exchange therapy
E) vitamins
B) acetylcholinesterase inhibitors
Acetylcholinesterase inhibitors: Myasthenia gravis is caused by
the disturbance of neuromuscular transmission due to the
damage to the postsynaptic membrane function triggered by the
anti-ACh-receptor antibody.
• 3
NEU - 6.3
Motor neurone disease:
A) Eaton–Lambert syndrome
B) Amyotrophic lateral sclerosis
C) Duchenne muscular dystrophy
D) Guillain–Barré syndrome
B) Amyotrophic lateral sclerosis
Eaton-Lambert-syndrome is the disease of the presynaptic
neuromuscular transmission (usually caused by anti-calcium
channel antibodies of paraneoplastic origin) Amyotrophic lateral
sclerosis: signs of both upper and lower motor neuron lesion
can be observed Duchenne disease: X-linked muscular
dystrophy of recessive inheritance Guillain-Barré-syndrome:
, inflammatory, immune-mediated polyganglioradiculitis with
segmental demyelinisation.
• 4
NEU - 6.4
Which symptom is not characteristic for Amyotrophic
lateral sclerosis?
A) Babinski-reflex (extensor plantar reflex)
B) atrophy of the small hand muscles
C) fasciculation
D) dysphagia
E) paraesthesia
E) paraesthesia
Paraesthesia: not a sign of ALS. Sensory system is not affected
in this disease. ALS is a disease of both the lower and upper
motor neurons (with the degeneration of the corticospinal tract).
• 5
NEU - 6.5
Which is not characteristic for Guillain–Barré syndrome?
A) albuminocytologic dissociation in the CSF
B) ascending paresis
C) cranial nerves are never affected
