OBJECTIVE ASSESSMENT 2026 | VERIFIED
ACTUAL EXAM QUESTIONS & DETAILED
ANSWERS WITH RATIONALES | COMPLETE OA
PASS GUIDE
WGU D312 ANATOMY & PHYSIOLOGY I
OBJECTIVE ASSESSMENT 2026
VERIFIED EXAM QUESTIONS WITH DETAILED ANSWERS & RATIONALE
Question 1 Which level of structural organization is the MOST basic level in the human
body?
A. Cellular level
B. Chemical level
C. Tissue level
D. Organ level
E. Organismal level
CORRECT ANSWER: B. Chemical level
RATIONALE: The chemical level is the most basic level of structural organization,
consisting of atoms and molecules. Everything in the body is built from chemical
components — atoms combine to form molecules, which form organelles, then cells,
tissues, organs, organ systems, and finally the organism.
Question 2 Which term describes the study of the FUNCTIONS of body structures?
A. Anatomy
B. Cytology
C. Histology
D. Physiology
,E. Pathology
CORRECT ANSWER: D. Physiology
RATIONALE: Physiology is the study of how body structures function. Anatomy refers
to the study of body structure. Cytology is the study of cells, histology is the study of
tissues, and pathology is the study of disease.
Question 3 A patient is standing upright, facing forward, with palms facing anteriorly.
This describes which anatomical position?
A. Prone position
B. Lateral recumbent position
C. Supine position
D. Fowler's position
E. Standard anatomical position
CORRECT ANSWER: E. Standard anatomical position
RATIONALE: The standard anatomical position is defined as standing erect, facing
forward, feet together, with palms facing anteriorly (forward). This position is the
reference point for all directional terminology in anatomy.
Question 4 Which directional term means CLOSER to the point of attachment of a limb
to the trunk?
A. Distal
B. Lateral
C. Proximal
D. Inferior
E. Superficial
CORRECT ANSWER: C. Proximal
RATIONALE: Proximal means closer to the point of origin or attachment of a limb to
the trunk. For example, the elbow is proximal to the wrist. Distal is the opposite —
farther from the point of attachment.
,Question 5 Which body cavity contains the heart and lungs?
A. Abdominal cavity
B. Pelvic cavity
C. Cranial cavity
D. Thoracic cavity
E. Spinal cavity
CORRECT ANSWER: D. Thoracic cavity
RATIONALE: The thoracic cavity is located within the chest and contains the heart (in
the mediastinum) and the lungs (in the pleural cavities). The abdominal cavity contains
digestive organs, and the pelvic cavity contains reproductive and urinary organs.
Question 6 Which plane divides the body into LEFT and RIGHT portions?
A. Transverse plane
B. Frontal plane
C. Coronal plane
D. Sagittal plane
E. Oblique plane
CORRECT ANSWER: D. Sagittal plane
RATIONALE: The sagittal plane divides the body into left and right portions. A
midsagittal (median) plane divides the body into equal left and right halves. The frontal
(coronal) plane divides the body into anterior and posterior portions, while the
transverse plane divides it into superior and inferior portions.
Question 7 Which of the following BEST describes homeostasis?
A. The process of cell division
B. The maintenance of a stable internal environment
C. The study of organ systems
, D. The breakdown of nutrients for energy
E. The process of tissue repair
CORRECT ANSWER: B. The maintenance of a stable internal environment
RATIONALE: Homeostasis refers to the body's ability to maintain a relatively stable
internal environment despite changes in external conditions. It involves constant
monitoring and adjustment of variables such as temperature, pH, blood glucose, and
blood pressure.
Question 8 In a negative feedback mechanism, the response of the effector:
A. Amplifies the original stimulus
B. Has no effect on the stimulus
C. Reverses or reduces the original stimulus
D. Increases hormone production permanently
E. Destroys the receptor
CORRECT ANSWER: C. Reverses or reduces the original stimulus
RATIONALE: In negative feedback, the effector's response counteracts the original
stimulus, returning the variable to its set point. This is the most common homeostatic
mechanism. For example, when blood glucose rises, insulin is released to bring it back
down.
Question 9 Which of the following is an example of POSITIVE feedback?
A. Regulation of blood glucose by insulin
B. Regulation of body temperature by sweating
C. Uterine contractions during childbirth
D. Regulation of blood pressure by baroreceptors
E. Calcium regulation by parathyroid hormone
CORRECT ANSWER: C. Uterine contractions during childbirth