ATI Pharmacology CMS
Retake Prep Practice
Questions: 150 Original
Items with Rationales ()
with NGN Questions and
Verified Answers 100%
Guarantee Pass
ATI Pharmacology CMS Practice Questions (1-100) with
Rationales
Question 1: A nurse is preparing to administer warfarin to a client. Which laboratory
value should the nurse monitor closely?
A. Hemoglobin
B. INR
C. Platelet count
D. Serum creatinine
,Correct Answer: B. INR
Rationale: Warfarin, an anticoagulant, requires monitoring of the International
Normalized Ratio (INR) to assess therapeutic effect and bleeding risk. Hemoglobin,
platelets, and creatinine are not directly affected by warfarin .
Question 2: A client with asthma is prescribed albuterol. Which adverse effect should
the nurse instruct the client to report?
A. Hypoglycemia
B. Tachycardia
C. Constipation
D. Weight gain
Correct Answer: B. Tachycardia
Rationale: Albuterol, a beta-2 agonist, can cause tachycardia as a common adverse
effect due to its stimulatory action on the heart. Other options are not typically
associated with albuterol .
Question 3: A nurse is administering morphine 10 mg IV to a client. Which finding
indicates a need to withhold the next dose?
A. Blood pressure 120/80 mmHg
B. Respiratory rate 8/min
C. Heart rate 70/min
D. Pain level 4/10
Correct Answer: B. Respiratory rate 8/min
Rationale: A respiratory rate of 8/min indicates respiratory depression, a serious
,adverse effect of morphine. The nurse should withhold the dose and notify the
provider .
Question 4: A client is prescribed levothyroxine for hypothyroidism. Which instruction
should the nurse include?
A. Take with food to enhance absorption
B. Take at the same time each day
C. Skip doses if feeling jittery
D. Take at bedtime with milk
Correct Answer: B. Take at the same time each day
Rationale: Levothyroxine should be taken consistently at the same time daily, preferably
on an empty stomach, to ensure stable thyroid levels. Food and milk can decrease
absorption; skipping doses is unsafe .
Question 5: A nurse is caring for a client receiving heparin. Which laboratory value
warrants an incident report?
A. aPTT 30 seconds
B. aPTT 90 seconds
C. INR 1.2
D. Platelet count 150,000/mm³
Correct Answer: B. aPTT 90 seconds
Rationale: An aPTT of 90 seconds is significantly elevated, indicating a risk of bleeding
with heparin therapy. Normal therapeutic aPTT is 1.5–2.5 times the control value (e.g.,
60–80 seconds) .
, Question 6: A client with diabetes is prescribed metformin. What is the primary
therapeutic effect?
A. Lowers blood pressure
B. Decreases blood glucose
C. Increases heart rate
D. Reduces seizure activity
Correct Answer: B. Decreases blood glucose
Rationale: Metformin decreases hepatic glucose production and improves insulin
sensitivity, lowering blood glucose. It does not affect blood pressure, heart rate, or
seizures .
Question 7: A nurse is preparing to administer insulin lispro. Where should the nurse
inject it?
A. Deltoid muscle
B. Abdomen
C. Gluteal muscle
D. Vastus lateralis
Correct Answer: B. Abdomen
Rationale: Insulin lispro, a rapid-acting insulin, is best absorbed in the abdomen due to
its subcutaneous fat and consistent blood flow. Other sites are less optimal for rapid-
acting insulin .
Retake Prep Practice
Questions: 150 Original
Items with Rationales ()
with NGN Questions and
Verified Answers 100%
Guarantee Pass
ATI Pharmacology CMS Practice Questions (1-100) with
Rationales
Question 1: A nurse is preparing to administer warfarin to a client. Which laboratory
value should the nurse monitor closely?
A. Hemoglobin
B. INR
C. Platelet count
D. Serum creatinine
,Correct Answer: B. INR
Rationale: Warfarin, an anticoagulant, requires monitoring of the International
Normalized Ratio (INR) to assess therapeutic effect and bleeding risk. Hemoglobin,
platelets, and creatinine are not directly affected by warfarin .
Question 2: A client with asthma is prescribed albuterol. Which adverse effect should
the nurse instruct the client to report?
A. Hypoglycemia
B. Tachycardia
C. Constipation
D. Weight gain
Correct Answer: B. Tachycardia
Rationale: Albuterol, a beta-2 agonist, can cause tachycardia as a common adverse
effect due to its stimulatory action on the heart. Other options are not typically
associated with albuterol .
Question 3: A nurse is administering morphine 10 mg IV to a client. Which finding
indicates a need to withhold the next dose?
A. Blood pressure 120/80 mmHg
B. Respiratory rate 8/min
C. Heart rate 70/min
D. Pain level 4/10
Correct Answer: B. Respiratory rate 8/min
Rationale: A respiratory rate of 8/min indicates respiratory depression, a serious
,adverse effect of morphine. The nurse should withhold the dose and notify the
provider .
Question 4: A client is prescribed levothyroxine for hypothyroidism. Which instruction
should the nurse include?
A. Take with food to enhance absorption
B. Take at the same time each day
C. Skip doses if feeling jittery
D. Take at bedtime with milk
Correct Answer: B. Take at the same time each day
Rationale: Levothyroxine should be taken consistently at the same time daily, preferably
on an empty stomach, to ensure stable thyroid levels. Food and milk can decrease
absorption; skipping doses is unsafe .
Question 5: A nurse is caring for a client receiving heparin. Which laboratory value
warrants an incident report?
A. aPTT 30 seconds
B. aPTT 90 seconds
C. INR 1.2
D. Platelet count 150,000/mm³
Correct Answer: B. aPTT 90 seconds
Rationale: An aPTT of 90 seconds is significantly elevated, indicating a risk of bleeding
with heparin therapy. Normal therapeutic aPTT is 1.5–2.5 times the control value (e.g.,
60–80 seconds) .
, Question 6: A client with diabetes is prescribed metformin. What is the primary
therapeutic effect?
A. Lowers blood pressure
B. Decreases blood glucose
C. Increases heart rate
D. Reduces seizure activity
Correct Answer: B. Decreases blood glucose
Rationale: Metformin decreases hepatic glucose production and improves insulin
sensitivity, lowering blood glucose. It does not affect blood pressure, heart rate, or
seizures .
Question 7: A nurse is preparing to administer insulin lispro. Where should the nurse
inject it?
A. Deltoid muscle
B. Abdomen
C. Gluteal muscle
D. Vastus lateralis
Correct Answer: B. Abdomen
Rationale: Insulin lispro, a rapid-acting insulin, is best absorbed in the abdomen due to
its subcutaneous fat and consistent blood flow. Other sites are less optimal for rapid-
acting insulin .