CPJE PNN Top 400 – Questions With Detailed
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Terms in this set (860)
Diuretics SULFA allergy with all thiazides
LOOPs watch for SULFA allergy except for
Ethacrynic Acid
TD - not if renal impairment
- low Na, Cl, K, Mg
- high Ca, glucose, lipid, UA
- sexual dysfunction, rash, photosensitivity
- risk of lithium toxicity (low Na)
- risk of digoxin toxicity (low K and Mg)
- risk of allopurinol hypersensitivity
- pregnancy cat B
LD - okay if renal impairment
- decrease all electrolytes low Na, Cl, K, Mg, Ca
- high glucose, lipid, UA
- sexual dysfunction, rash, photosensitivity
- lupus, ototoxicity (ethacrynic acid)
- ethacrynic acid 50mg = furosemide 40mg =
torsemide 20mg = bumetanide 1mg
,Bumex bumetanide
loop diuretic
sulfa allergy
Edema - 0.5, 1, 2 mg
PO - 0.5-2mg x 1; redose in 4-5 hrs x 2 doses
max 10mg/d
BID
1 mg bumex = 40mg lasix
Edecrin ethacrynic acid
loop diuretic
PO/IV
highest ototoxicity of the loop diuretics
only loop diuretic without SULFA
Lasix furosemide
loop diuretic
1:2 - IV:PO
protect IV from light
tabs, oral solution, IM/IV
- HTN - 20-40 mg BID
- Edema, HF - 20-80mg/dose, up to 600mg/d
QD/BID
,Demadex torsemide
loop diuretic
SULFA allergy
htn - 5mg QD
max 100mg/d
chlorthalidone thiazide-like diuretic
12.5mg
max 100mg QD
longer acting/more potent than HCTZ
hydrochlorothiazide thiazide diuretic
12.5-25mg QD (up to 50mg)
daily in 1-2 divided doses
minimal response and more electrolyte disturbances
seen with doses >50mg daily
Maxzide, Dyazide - triamterene with HCTZ
Diuril chlorothiazide
thiazide diuretic
PO - 500-2000 mg QD
IV- 500-1000mg QD/BID
Lozol indapamide
thiazide-like diuretic
1.25mg
max 5mg QD
, Zaroxolyn metolazone
thiazide-like diuretic
2.5-5mg QD
target dose 20mg
thiazide-related that can be used in renal failure
K-sparing diuretics hyperkalemia
hyponatremia
rash, HA
weak diuretic
Midamor amiloride
K-sparing
5mg QD (max 20mg/d)
Dyrenium Triamterene
K-sparing
100-300mg QD/BID
max 300mg/d
form - capsules only
Aldactone spironolactone
aldosterone antagonists
gynecomastia
BP lowering in pts with hyperaldosteronism
HTN - 50-100mg QD/BID
Edema - 25-200 mg QD/BID
HF (NYHA class 3-4) - 12.5-25mg QD (max 50mg)
with food
Solutions
Save
Terms in this set (860)
Diuretics SULFA allergy with all thiazides
LOOPs watch for SULFA allergy except for
Ethacrynic Acid
TD - not if renal impairment
- low Na, Cl, K, Mg
- high Ca, glucose, lipid, UA
- sexual dysfunction, rash, photosensitivity
- risk of lithium toxicity (low Na)
- risk of digoxin toxicity (low K and Mg)
- risk of allopurinol hypersensitivity
- pregnancy cat B
LD - okay if renal impairment
- decrease all electrolytes low Na, Cl, K, Mg, Ca
- high glucose, lipid, UA
- sexual dysfunction, rash, photosensitivity
- lupus, ototoxicity (ethacrynic acid)
- ethacrynic acid 50mg = furosemide 40mg =
torsemide 20mg = bumetanide 1mg
,Bumex bumetanide
loop diuretic
sulfa allergy
Edema - 0.5, 1, 2 mg
PO - 0.5-2mg x 1; redose in 4-5 hrs x 2 doses
max 10mg/d
BID
1 mg bumex = 40mg lasix
Edecrin ethacrynic acid
loop diuretic
PO/IV
highest ototoxicity of the loop diuretics
only loop diuretic without SULFA
Lasix furosemide
loop diuretic
1:2 - IV:PO
protect IV from light
tabs, oral solution, IM/IV
- HTN - 20-40 mg BID
- Edema, HF - 20-80mg/dose, up to 600mg/d
QD/BID
,Demadex torsemide
loop diuretic
SULFA allergy
htn - 5mg QD
max 100mg/d
chlorthalidone thiazide-like diuretic
12.5mg
max 100mg QD
longer acting/more potent than HCTZ
hydrochlorothiazide thiazide diuretic
12.5-25mg QD (up to 50mg)
daily in 1-2 divided doses
minimal response and more electrolyte disturbances
seen with doses >50mg daily
Maxzide, Dyazide - triamterene with HCTZ
Diuril chlorothiazide
thiazide diuretic
PO - 500-2000 mg QD
IV- 500-1000mg QD/BID
Lozol indapamide
thiazide-like diuretic
1.25mg
max 5mg QD
, Zaroxolyn metolazone
thiazide-like diuretic
2.5-5mg QD
target dose 20mg
thiazide-related that can be used in renal failure
K-sparing diuretics hyperkalemia
hyponatremia
rash, HA
weak diuretic
Midamor amiloride
K-sparing
5mg QD (max 20mg/d)
Dyrenium Triamterene
K-sparing
100-300mg QD/BID
max 300mg/d
form - capsules only
Aldactone spironolactone
aldosterone antagonists
gynecomastia
BP lowering in pts with hyperaldosteronism
HTN - 50-100mg QD/BID
Edema - 25-200 mg QD/BID
HF (NYHA class 3-4) - 12.5-25mg QD (max 50mg)
with food
