CPJE law, CPJE 2026 Study Guide – Questions With
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Terms in this set (1985)
APAP/Tylenol -Antipyretic /Analgesics
-not an anti-inflammatory
-DOC in pregnancy and use with warfarin
-Hepatoxicity
- max 4g/day normal adults
-max 3 g/day in pts with renal impairment
-IV APAP -ofirmev
-child dose: 10-15 mg/kg q4-6hrs
-antidote -N-acetylcysteine
+ hydrocodone =vicodin,lortab and Narco (C2)
+oxycodone=percocet, Endocet (C2)
+ codeine = Tylenol #2,3,4 ( 300/15, 300/30, (300/60)
(C3)
+tramadol=Ultram (C3)
+dihenhydramine =tylenol PM
oxycodone ER/apap --> Xartemis XR
NSAIDS -Aspirin -Irreversible inhibit cox1 and cox 2
-Antiplatele
-dosing 81-325 mg
-81 mg is cardioprotection
->3.6g/d is anti-inflammatory
-overdose: Tinnitus (caution with other ototoxic drugs
( vanco, aminog, thiazide , loop)
-CI in pregrnancy
-Avoid in children at < 16 yrs with any viral infection
due to potential risk reye's syndrome
-Brand name : Bayer, ascriptin, Bufferin, Ecotrin
-GI Toxic
,NSAIDS-NON SELECTIVE used to treat pain, fever and inflammation
increase BP
dispensed with a med guide(including OTC)
renal toxicity in comb with diuretics and ACE/ARB
hepatoxic toxic -least risk ibuprofen and celecoxib
SE-asthma exacerbation ,anemia , skin rash
BBW -GI BLEEDING
Limit alcohol use
do not use with steroids , anticoag ( warfarin,
pradaxa,or xarelto )
Take with food to decrease nausea/stomach upset
Chronic use protect the stomach gut with PPI OR
MISOPROSTOL.
limit sun exposure
stop a week before CABG Surgery
Naproxen ( ALEVE -220 mg BID ) (naprosyn,
Naprelan, Anaprox) --> higher GI SE, Less thrombotic
risk
Vimovo- Esomeprazole +naproxen
Indomethacin (Indocin ) --> ( IR:25-50 mg)
-approved for gout
-avoid in psych conditions and GI toxicity
==>protect gut
Piroxicam (feldene ) - only use if failed other NSAID.
Most GI toxicity and sever skin reaction (SJS)-->
PROTECT stomach with PPI OR misoprostol
Ketorolac (toradol)- highest GI toxicity --> 5 days
only --> give PO only after IM /IV (one time only)
NASAL(spirix) SE: bleeding, anaphylaxis
Ibuprofen ( advil, motrin ) -lowest GI risk
OTC- 200-400 MG Q6-8HRS (max 5 dose)
MAX :3.2g
Child dose: 5-10 mg /kg /q6-8hrs
Iv ibuprofen-caldolor
oxaprozin (daypro) -similar to piroxicam
Ketoprofen (orudis) -high Gi risk
nabumetone (relafen)
,NSAIDS COX 2 SELECTIVE bbw: CV thrombotic events MI and Stroke (except
aspirin )
Low bleeding risk
Celocoxib (celebrex) --> CI in sulfa allergy
adjust renal disease
- dont give after 30 week of preg
Meloxicam (mobic)
etodolac (lodine
Diflunisal (dolobid)
Diclofenac ( cataflam, voltaren XR) --> CV RISK
Diclofenac +misoprostol ==> arthrotec
NSAID USED IN RENAL IMPAIRMENT Sulindac ( clinoril )
AntiRheumatic agents
Muscle relaxants Avoid alcohol (cns depression )
may cause drowsiness dizziness -do not operate
machinery
Do not stop abruptly ( withdrawal - lioresal, soma
zanaflex )
Soma is C-IV
fLEXERIL, AMRIX, FEXMID -do not use with MAOI
within 14 DAYS
Zanaflex -take with or without food but be consistent
, opioid agonist bbw- all controlled release should not be taken with
alcohol
CNS Depression
Report allergic reaction
constipation-senna and ducolax ---->if nothing work
----> methylnaltrexone ( relistor)
Use of codeine is CI in all children less than 12 years
because it causes resp .depression AND in child 12-18
who are obese or have certain conditions (sleep
apnea ) ....should not be used in children <18 yrs
following a tonsillectomy and or adenoidectormy
procedures.
Do not use codeine in breastfeeding
Avoid codeine in rapid metabolizers
AUX :
Controlled substance cannot be filled without RX
May cause drowsiness
do not operate machinery
do not drink alcohol
do not share
take with food or milk
Medguide
Lidoderm lidoderm 5 % patch
12 hours on and 12 hours off..max 3 patch per day
...can cut into smaller
used for shingles pain
Expert Solutions
Save
Terms in this set (1985)
APAP/Tylenol -Antipyretic /Analgesics
-not an anti-inflammatory
-DOC in pregnancy and use with warfarin
-Hepatoxicity
- max 4g/day normal adults
-max 3 g/day in pts with renal impairment
-IV APAP -ofirmev
-child dose: 10-15 mg/kg q4-6hrs
-antidote -N-acetylcysteine
+ hydrocodone =vicodin,lortab and Narco (C2)
+oxycodone=percocet, Endocet (C2)
+ codeine = Tylenol #2,3,4 ( 300/15, 300/30, (300/60)
(C3)
+tramadol=Ultram (C3)
+dihenhydramine =tylenol PM
oxycodone ER/apap --> Xartemis XR
NSAIDS -Aspirin -Irreversible inhibit cox1 and cox 2
-Antiplatele
-dosing 81-325 mg
-81 mg is cardioprotection
->3.6g/d is anti-inflammatory
-overdose: Tinnitus (caution with other ototoxic drugs
( vanco, aminog, thiazide , loop)
-CI in pregrnancy
-Avoid in children at < 16 yrs with any viral infection
due to potential risk reye's syndrome
-Brand name : Bayer, ascriptin, Bufferin, Ecotrin
-GI Toxic
,NSAIDS-NON SELECTIVE used to treat pain, fever and inflammation
increase BP
dispensed with a med guide(including OTC)
renal toxicity in comb with diuretics and ACE/ARB
hepatoxic toxic -least risk ibuprofen and celecoxib
SE-asthma exacerbation ,anemia , skin rash
BBW -GI BLEEDING
Limit alcohol use
do not use with steroids , anticoag ( warfarin,
pradaxa,or xarelto )
Take with food to decrease nausea/stomach upset
Chronic use protect the stomach gut with PPI OR
MISOPROSTOL.
limit sun exposure
stop a week before CABG Surgery
Naproxen ( ALEVE -220 mg BID ) (naprosyn,
Naprelan, Anaprox) --> higher GI SE, Less thrombotic
risk
Vimovo- Esomeprazole +naproxen
Indomethacin (Indocin ) --> ( IR:25-50 mg)
-approved for gout
-avoid in psych conditions and GI toxicity
==>protect gut
Piroxicam (feldene ) - only use if failed other NSAID.
Most GI toxicity and sever skin reaction (SJS)-->
PROTECT stomach with PPI OR misoprostol
Ketorolac (toradol)- highest GI toxicity --> 5 days
only --> give PO only after IM /IV (one time only)
NASAL(spirix) SE: bleeding, anaphylaxis
Ibuprofen ( advil, motrin ) -lowest GI risk
OTC- 200-400 MG Q6-8HRS (max 5 dose)
MAX :3.2g
Child dose: 5-10 mg /kg /q6-8hrs
Iv ibuprofen-caldolor
oxaprozin (daypro) -similar to piroxicam
Ketoprofen (orudis) -high Gi risk
nabumetone (relafen)
,NSAIDS COX 2 SELECTIVE bbw: CV thrombotic events MI and Stroke (except
aspirin )
Low bleeding risk
Celocoxib (celebrex) --> CI in sulfa allergy
adjust renal disease
- dont give after 30 week of preg
Meloxicam (mobic)
etodolac (lodine
Diflunisal (dolobid)
Diclofenac ( cataflam, voltaren XR) --> CV RISK
Diclofenac +misoprostol ==> arthrotec
NSAID USED IN RENAL IMPAIRMENT Sulindac ( clinoril )
AntiRheumatic agents
Muscle relaxants Avoid alcohol (cns depression )
may cause drowsiness dizziness -do not operate
machinery
Do not stop abruptly ( withdrawal - lioresal, soma
zanaflex )
Soma is C-IV
fLEXERIL, AMRIX, FEXMID -do not use with MAOI
within 14 DAYS
Zanaflex -take with or without food but be consistent
, opioid agonist bbw- all controlled release should not be taken with
alcohol
CNS Depression
Report allergic reaction
constipation-senna and ducolax ---->if nothing work
----> methylnaltrexone ( relistor)
Use of codeine is CI in all children less than 12 years
because it causes resp .depression AND in child 12-18
who are obese or have certain conditions (sleep
apnea ) ....should not be used in children <18 yrs
following a tonsillectomy and or adenoidectormy
procedures.
Do not use codeine in breastfeeding
Avoid codeine in rapid metabolizers
AUX :
Controlled substance cannot be filled without RX
May cause drowsiness
do not operate machinery
do not drink alcohol
do not share
take with food or milk
Medguide
Lidoderm lidoderm 5 % patch
12 hours on and 12 hours off..max 3 patch per day
...can cut into smaller
used for shingles pain
