MMSC436 (chem) final exam
1. In a patient with suspected primary hyperthyroidism associated with Graves'
disease, one would expect the following laboratory serum results: T4
....................., TSH ......................
Decreased, normal Increased,
decreased Normal, increase,
increased
Increased, normal: increased, decreased
2. The major fraction of organic iodine circulating in the blood is:
Diiodotyrosine
Tetraiodothyronine
Thyroglobulin Triiodothyronine:
Tetraiodothyronine
3. During pregnancy, serum TBG concentration ..........., total thyroid hormone
levels are ..........., and free thyroid hormone levels are .......
increases, increased, unaffected
is unaffected, increased, increased
,decreases, decreases, unaffected
is unaffected, decreased, decreased: increases, increased, unaffected
4. Which one of the following statements about T3 is FALSE?
-It is not bound to serum proteins
-It is commonly decreased in patients with nonthyroidal illness.
-It is thought to be the most active thyroid hormone.
- It may be elevated to a greater extent than T4 in hyperthyroidism.: It is not bound to serum
proteins
5. The old T3 resin uptake test has been replaced by a direct assay for:
Circulating free T3
Binding capacity of thyroxine-binding globulin
Thyroxine-binding globulin
Thyroglobulin
Bound T3: Bound T3
6. A two-year-old child with a decreased serum T4 is described as being some- what
dwarfed, stocky, and overweight and having coarse features. Of the following, the
most informative additional laboratory test would be serum:
,Thyroid-stimulating hormone (TSH)
Thyroxine-binding globulin (TBG)
Triiodothyronine (T3)
Cholesterol: Thyroid-stimulating hormone (TSH)
7. What tests are used as part of newborn screening programs to identify
congenital hypothyroidism?
T3 and/or T4
fT3 and/or T4
T3 and/or TSH
T4 and/or TSH: T4 and/or TSH
8. The TRH (thyrotropin releasing hormone) stimulation test is useful in
differentiating hypothalamic hypothyroidism from:
Sub-clinical hypothyroidism
Hashimoto's thyroiditis
Primary hypothyroidism
Pituitary hypothyroidism: Pituitary hypothyroidism
9. True or false? When taken by a euthyroid individual, oral contraceptives will have
an increasing effect on thyroxine binding globulin.
, True False:
True
10. True or false? Individuals taking recurring regimens of androgens or anabolic
steroid drugs may exhibit increased TBG levels.
True False:
False
11. The primary physiological regulator of parathyroid hormone (PTH) synthesis
and secretion is:
-the concentration of PTH in blood.
-PTH stimulating hormone.
-PTH releasing hormone from the pituitary gland.
-the concentration of free calcium in blood or extracellular fluid.: the concentration of free
calcium in blood or extracellular fluid.
12. Hypoparathyroidism is most commonly caused by:
-parathyroid gland destruction.
-pseudohypoparathyroidism.
-adenoma of the parathyroid gland.
1. In a patient with suspected primary hyperthyroidism associated with Graves'
disease, one would expect the following laboratory serum results: T4
....................., TSH ......................
Decreased, normal Increased,
decreased Normal, increase,
increased
Increased, normal: increased, decreased
2. The major fraction of organic iodine circulating in the blood is:
Diiodotyrosine
Tetraiodothyronine
Thyroglobulin Triiodothyronine:
Tetraiodothyronine
3. During pregnancy, serum TBG concentration ..........., total thyroid hormone
levels are ..........., and free thyroid hormone levels are .......
increases, increased, unaffected
is unaffected, increased, increased
,decreases, decreases, unaffected
is unaffected, decreased, decreased: increases, increased, unaffected
4. Which one of the following statements about T3 is FALSE?
-It is not bound to serum proteins
-It is commonly decreased in patients with nonthyroidal illness.
-It is thought to be the most active thyroid hormone.
- It may be elevated to a greater extent than T4 in hyperthyroidism.: It is not bound to serum
proteins
5. The old T3 resin uptake test has been replaced by a direct assay for:
Circulating free T3
Binding capacity of thyroxine-binding globulin
Thyroxine-binding globulin
Thyroglobulin
Bound T3: Bound T3
6. A two-year-old child with a decreased serum T4 is described as being some- what
dwarfed, stocky, and overweight and having coarse features. Of the following, the
most informative additional laboratory test would be serum:
,Thyroid-stimulating hormone (TSH)
Thyroxine-binding globulin (TBG)
Triiodothyronine (T3)
Cholesterol: Thyroid-stimulating hormone (TSH)
7. What tests are used as part of newborn screening programs to identify
congenital hypothyroidism?
T3 and/or T4
fT3 and/or T4
T3 and/or TSH
T4 and/or TSH: T4 and/or TSH
8. The TRH (thyrotropin releasing hormone) stimulation test is useful in
differentiating hypothalamic hypothyroidism from:
Sub-clinical hypothyroidism
Hashimoto's thyroiditis
Primary hypothyroidism
Pituitary hypothyroidism: Pituitary hypothyroidism
9. True or false? When taken by a euthyroid individual, oral contraceptives will have
an increasing effect on thyroxine binding globulin.
, True False:
True
10. True or false? Individuals taking recurring regimens of androgens or anabolic
steroid drugs may exhibit increased TBG levels.
True False:
False
11. The primary physiological regulator of parathyroid hormone (PTH) synthesis
and secretion is:
-the concentration of PTH in blood.
-PTH stimulating hormone.
-PTH releasing hormone from the pituitary gland.
-the concentration of free calcium in blood or extracellular fluid.: the concentration of free
calcium in blood or extracellular fluid.
12. Hypoparathyroidism is most commonly caused by:
-parathyroid gland destruction.
-pseudohypoparathyroidism.
-adenoma of the parathyroid gland.
