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HESI RN ADVANCED PHARMACOLOGY MIDTERM EXAM |ACTUAL
EXAM QUESTIONS WITH CORRECT ANSWERS (100% VERIFIED)
|NEWEST UPDATE 2026 ALREADY GRADED A+
1. The study of drug absorption, distribution, metabolism, and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology - ✓✓ ANS- C
2. The medical situation when a particular drug should not be administered is referred to as
A. side effect
B. adverse effect
C. drug allergy
D. contraindication
E. antagonism - ✓✓ ANS- D
3. An unusual or unexpected drug reaction by an individual is known as
A. toxic effect
B. antagonism
C. idiosyncrasy
D. side effect
E. drug allergy - ✓✓ ANS- C
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4. The proprietary drug name supplied by a pharmaceutical company is also referred to as the
A. generic name
B. over-the-counter name
C. trade name
D. chemical name
E. none of these - ✓✓ ANS- C
5. The time from drug administration to the first observable drug effect is known as the
A. duration of action
B. onset of action
C. ceiling effect
D. maximal response
E. ceiling effect - ✓✓ ANS- B
6. A drug that has the potential for abuse and is regulated by the Drug Enforcement Agency is classified as a
A. poison
B. OTC drug
C. prescription drug
D. controlled substance
E. nonproprietary drug - ✓✓ ANS- D
7. Select the term below that relates to the amount of drug administered to produce a therapeutic effect.
A. posology
B. toxicology
C. pharmacodynamics
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D. pharmacotherapeutics
E. pharmacy - ✓✓ ANS- A
8. A medication that does not require a physician's service to obtain is referred to as
A. trade
B. nonproprietary
C. nonprescription
D. brand
E. generic - ✓✓ ANS- C
9. Which of the following could be categorized as an adverse reaction?
A. idiosyncrasy
B. drug allergy
C. teratogenicity
D. carcinogenicity
E. all of these - ✓✓ ANS- E
10. The time a drug continues to produce its effect is its
A. ED50
B. maximal response
C. ceiling effect
D. onset of action
E. duration of action - ✓✓ ANS- E
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11. The drug administration route demonstrating the slowest onset of action is
A. inhalation
B. transdermal
C. intramuscular
D. sublingual
E. intravenous - ✓✓ ANS- B
12. In order for drugs to cross the blood-brain barrier, they must be
A. ionized
B. positively charged
C. water soluble
D. lipid soluble
E. negatively charged - ✓✓ ANS- D
13. First-pass metabolism refers to the metabolism of drugs in the
A. kidney
B. blood vessels
C. liver
D. heart
E. adipose tissue - ✓✓ ANS- C
14. Drug X has a half-life of 6 hours. How much drug is left in the body 18 hours after an IV injection of 1200
milligrams (mg)? - ✓✓ ANS- B
15. Drugs that have demonstrated teratogenic effects in women are classified as Pregnancy Category
A. B
HESI RN ADVANCED PHARMACOLOGY MIDTERM EXAM |ACTUAL
EXAM QUESTIONS WITH CORRECT ANSWERS (100% VERIFIED)
|NEWEST UPDATE 2026 ALREADY GRADED A+
1. The study of drug absorption, distribution, metabolism, and excretion is known as
A. pharmacotherapeutics
B. pharmacodynamics
C. pharmacokinetics
D. pharmacy
E. posology - ✓✓ ANS- C
2. The medical situation when a particular drug should not be administered is referred to as
A. side effect
B. adverse effect
C. drug allergy
D. contraindication
E. antagonism - ✓✓ ANS- D
3. An unusual or unexpected drug reaction by an individual is known as
A. toxic effect
B. antagonism
C. idiosyncrasy
D. side effect
E. drug allergy - ✓✓ ANS- C
,2|Page
4. The proprietary drug name supplied by a pharmaceutical company is also referred to as the
A. generic name
B. over-the-counter name
C. trade name
D. chemical name
E. none of these - ✓✓ ANS- C
5. The time from drug administration to the first observable drug effect is known as the
A. duration of action
B. onset of action
C. ceiling effect
D. maximal response
E. ceiling effect - ✓✓ ANS- B
6. A drug that has the potential for abuse and is regulated by the Drug Enforcement Agency is classified as a
A. poison
B. OTC drug
C. prescription drug
D. controlled substance
E. nonproprietary drug - ✓✓ ANS- D
7. Select the term below that relates to the amount of drug administered to produce a therapeutic effect.
A. posology
B. toxicology
C. pharmacodynamics
,3|Page
D. pharmacotherapeutics
E. pharmacy - ✓✓ ANS- A
8. A medication that does not require a physician's service to obtain is referred to as
A. trade
B. nonproprietary
C. nonprescription
D. brand
E. generic - ✓✓ ANS- C
9. Which of the following could be categorized as an adverse reaction?
A. idiosyncrasy
B. drug allergy
C. teratogenicity
D. carcinogenicity
E. all of these - ✓✓ ANS- E
10. The time a drug continues to produce its effect is its
A. ED50
B. maximal response
C. ceiling effect
D. onset of action
E. duration of action - ✓✓ ANS- E
, 4|Page
11. The drug administration route demonstrating the slowest onset of action is
A. inhalation
B. transdermal
C. intramuscular
D. sublingual
E. intravenous - ✓✓ ANS- B
12. In order for drugs to cross the blood-brain barrier, they must be
A. ionized
B. positively charged
C. water soluble
D. lipid soluble
E. negatively charged - ✓✓ ANS- D
13. First-pass metabolism refers to the metabolism of drugs in the
A. kidney
B. blood vessels
C. liver
D. heart
E. adipose tissue - ✓✓ ANS- C
14. Drug X has a half-life of 6 hours. How much drug is left in the body 18 hours after an IV injection of 1200
milligrams (mg)? - ✓✓ ANS- B
15. Drugs that have demonstrated teratogenic effects in women are classified as Pregnancy Category
A. B
