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ATI Pharmacology Proctored Exam 2026: Practice Questions with Detailed Solutions & Answers

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Master the ATI Pharmacology proctored exam with this comprehensive practice guide featuring updated questions and detailed solutions with highlighted correct answers. Covers essential pharmacology topics including cardiovascular medications (digoxin, furosemide, nitroglycerin, warfarin, heparin), antibiotics (penicillin, gentamicin, vancomycin, cefuroxime), psychiatric medications (lithium, sertraline, paroxetine, clozapine, carbamazepine), respiratory drugs (theophylline, fluticasone, cromolyn), endocrine medications (insulin types, metformin, glipizide, levothyroxine), pain management (morphine, hydromorphone, fentanyl, naloxone), and adverse effects, drug interactions, and client teaching. Includes dosage calculations, medication administration sequences, and critical thinking scenarios. Essential for nursing students preparing for ATI proctored exams and NCLEX-RN.

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ATI PHARMACOLOGY PROCTORED EXAM UPDATE
QUESTIONS WITH CORRECT DETAILED SOLUTIONS
HIGHLIGHTED


A nurse is preparing to administer digoxin orally to a client. Identify the sequence of
steps the nurse should take. (Move the steps into the box on the right placing them in the
order of performance. Use all the steps.)

a. Obtain the client's apical heart rate
b. Remove the medication from the
dispensing system
c. Open the medication package
d. Compare the client's wristband to
the medication administration record
e. Document administration of
the medication


A nurse is reviewing the medical record of an adult client who has a fever and a
prescription for acetaminophen. Which of the following findings should the nurse
identify as a contraindication for receiving this medication?

a. Alcohol use disorder
b. Chronic kidney disease
c. Hepatitis B vaccine within the last week
d. Diabetes mellitus

a. Alcohol use disorder
b. Chronic kidney disease




A home health nurse is visiting a client who has heart failure and a prescription for
furosemide.
The nurse identifies that the client has gained 2.5 kg (5 lb.) since the last visit 2 days ago.
Which of the following actions should the nurse take first?

a. Encourage the client to dangle the legs while sitting in a chair
b. Teach the client about foods low in sodium
C. Determine medication adherence by the client

,d. Notify the provider of the client's weight gain


C. Determine medication
adherence by the client




A nurse is preparing to administer the initial dose of penicillin G IM to a client. The
nurse should monitor for which of the following as an indication of an allergic
reaction following the injection?

a. Urticaria
b. Bradycardia
c. Pallor
d. Dyspepsia
a. Urticaria




A nurse is teaching a client who has angina a new prescription for sublingual
nitroglycerin tablets. Which of the following instructions should the nurse include in
the teaching?

a. "Discard any tablets you do not use every 6 months."
b. "Take one tablet each morning 30 minutes prior to eating
C. "Keep the tablets at room temperature in their original glass bottle.
d. "Place the tablet between your cheek and gum to dissolve"


C. "Keep the tablets at room
temperature in their original glass
bottle."




A nurse is providing teaching to a client who has a new prescription for theophylline a
sustained-released capsule. Which of the following statements by the client indicates an
understanding of the teaching?

a. "I can take my medication in the morning with my coffee."
b. "I may sprinkle the medication in applesauce."
C. "I should limit my fluid intake while on this medication.
d. "I will need to have blood levels drawn."




a. "I can take my medication in the

,morning with my coffee.' (DO NOT TAKE THEOPHILLE WITH CAFFEINE, INCREASES CNS
EFFECTS)




A nurse is mixing regular insulin and NPH insulin in the same syringe prior to
administering it to client who has diabetes mellitus following actions should the nurse
take first?

a. Withdraw the regular insulin from the viral
b. Withdraw the NPH insulin form the vial
Inject air into the NPH via c.l
d. Inject air into the regular insulin vial




C. Inject air into the NPH vial




A nurse is assessing a client who is receiving intravenous therapy. The nurse should
identify which of the following findings as a manifestation of fluid volume excess?

a. Decreased bowel sounds
b. Distended neck veins
c. Bilateral muscle weakness
d. Thread pulse




b. Distended neck veins


A nurse is caring for a client who has hyponatremia and is receiving an infusion of a
prescribed hypertonic solution. Which of the following findings should indicate to the
nurse that the treatment is effective?

a. Absent Chvostek's sign
b. Improved cognition
C. Decreased vomiting
d. Cardiac arrhythmias absent


b. Improved cognition

, A nurse is teaching a client who has a new prescription for a nitroglycerin transdermal
patch. Which of the following instructions should the nurse include?

a. "Discontinue the patch if you experience a headache.
b. "Apply a new patch if you have chest pain.
C. "Cover the patch with dry gauze when taking a shower."
d. "Remove the patch prior to going to bed."




d. "Remove the patch prior to
going to bed.
A nurse is reviewing he laboratory results of a client who has a prescription for sodium
polystyrene sulfonate (Kayexalate) every 6 hr. which of the following should the nurse
report to the provider?

a. Creatinine 0.72 mg/dL
b. Sodium 138 mEq/L C. Magnesium 2 mEq/L
d. Potassium 5.2 mEq/L


d. Potassium 5.2 mEq/L

Hyperkalemia (serum potassium level greater than 5.0 mEq/L) increases the client risk for
fatal cardiac dysrhythmias. Kayexalate is used to decrease the serum potassium level so the
PN should monitor the client's serum potassium level




A nurse is caring for a client who has tuberculosis and is taking isoniazid and rifampin.
Which of the following outcomes indicates that the client is adhering to the medication
regimen?

The client has a negative sputum culture
a.
b. The client tests negative for HIV
C. The client has a positive purified protein derivative test
d. The client's liver function test results are within the expected reference range


a. The client has a negative sputum culture




A client is caring for a client who develops an anaphylactic reaction to IV administration.

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