evidence based practice (EBP) - Answers · Evidence based practice: the integration of the best
research evidence with clinical expertise and patients' needs and values
· EBP is not a "one size fits all" approach to healthcare
· EBP is not a cost-cutting practice or method for rationing healthcare services
Florence Nightingale - Answers Early nursing theory
● Most people agree that research in nursing began with Florence Nightingale in the mid 19th century
● Nightingale's Environmental Theory
○ "What nursing has to do is to put the patient in the best condition for nature to act upon him"
○ Derived from observations about patient experience
· Nightingale had discovered that the majority of deaths in the Crimea were due to poor sanitation
rather than casualties in battle. She wanted to persuade the government of the need for better
hygiene in hospitals
· It was discovered that the Barrack Hospital was built on a sewer, meaning patients were drinking
contaminated water. The hospital, along with other British army hospitals, was flushed out and
ventilation improved. Consequently, the death rate began to fall.
Levels of Evidence - Answers ● Meta-analysis of randomized controlled trials are at the pinnacle of
traditional evidence hierarchies for therapy questions
● The essence of a meta-analysis is that findings from each study are used to compute a common
index (an effect size)
Effect sizes are averaged across studies, yielding information about the relationship
Experimental - Answers ○ Researcher actively introduces intervention to address a question
○ Explicitly designed to test causal relationships
○ Clinical trial
Non-experimental - Answers ○ Researcher observes, but does not intervene
○ Collect data without introducing treatments
○ Observational study
Qualitative Studies - Answers ● Understanding people's perception of reality
● Data are based on observations, narratives, pictures, and text that can be summarized through
themes, categories, or other units
PICOT Question - Answers ● P: population of interest
● I: intervention or issue of interest
● C: comparison of interest
● O: outcome expected
● T: time needed for the intervention to achieve the outcome or the time in the course of the
disease/ symptom that the intervention is applied
Theory - Answers ● Two or more concepts and a set of propositions that form a logically interrelated
system, providing a mechanism for deducing hypotheses
● Abstract generalization that explains how phenomena are related
● Model: representation of phenomena and their interrelationships (diagram)
● Framework: underpinning a study (overall rationale)
Nursing Theories - Answers ● Usually described in three levels
○ Grand: attempts to explain large aspects of human experience (most abstract)
○ Middle-range: focuses on a specific aspect of human experience (i.e. stress, comfort, health
promotion)
○ Practice: developed for use within a specific range of nursing situations (limited, least abstract)
Quantitative - Answers ○ Understanding a reality that exists
○ Data are based on surveys, biological measures and other sources that can be quantified
numerically
○ Types
■ Descriptive
■ Correlational
■ Quasi-experimental
■ Experimental
Qualitative - Answers ○ Understanding people's perception of reality
, ○ Data are based on observations, narratives, pictures, and text that can be summarized through
themes, categories, or other units
○ Types
■ Phenomenological
■ Grounded theory
■ Ethnographic
■ Historical research
Basic - Answers ■ Extending information for the sake of knowledge
■ Discover a vaccine that you find in a lab
■ Finding out new information
■ Appropriate for discovering general principles for human behavior and biophysiologic processes
Applied - Answers ■ Examines how principles can be used to solve problems in nursing practice
■ Discovering solutions to immediate problems
■ How can it be used in real life
Pre-appraised - Answers ○ Combining other people's studies to come to a conclusion
○ Consensus recommendations
○ Evidence that has been selected from primary studies and evaluated for use by clinician
○ Authoritative group
■ Governmental bodies
■ Professional boards
■ National guideline clearinghouse (end this year)
○ Pro: usually easier to integrate into clinical practice
○ Con: worst case is biased opinion
Primary studies - Answers ● Original study
● Published in journals and used in practice
● Not pre-appraised for quality and use in practice
● Pros
○ Direct from source
○ Newest knowledge
● Cons
○ Need technical knowledge
○ May not link clearly to practice
Independent variable - Answers ○ Variable believed to affect the dependent variable
○ Predictor
○ "Cause"
○ Intervention must have comparison
Dependent variable - Answers ○ The variable a research is interested in
○ Outcome
○ "Effect"
Confounding - Answers ■ 3rd variable
■ Potential other cause
■ 3rd variable that influences both IV and DV
■ Correlation is not causation
meta-analysis - Answers ● Meta-analysis: systematic review and analysis of quantitative studies
● Statistically pools results from previous studies into single quantitative analysis
○ Systematic review + math = meta-analysis
● Meta-analyses of RCTs are the pinnacle of traditional evidence hierarchies
● Allows for application of scientific criteria
○ Sample size, statistical significance, measurement, bias, effect size
○ Describe averages
○ Test relationships
● Summary of state of knowledge
● Not appropriate for broad questions or when findings are substantially inconsistent
● Replicable, quantifiable method ("greater objectivity")
● Combines results from many people ("greater power")
Forest plots - Answers ■ Individual study results (squares)
■ Confidence intervals (line)