Questions and Answers
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1. This type of medication reduces nasal congestion by activating alpha1 recep-
tors on nasal blood vessels which causes vasoconstriction which in turn causes
shrinkage of the swollen membrane followed by nasal drainage
Answer: Sympathomimetics (Sudafed)
2. What does sympathomimetics affect?
Answer: Beta1 and beta2 (increase heart rate and BP)
3. What are 4 adverse effects of sympathomimetics?
Answer: 1. Rebound congestion
2. CNS stimulation
3. Cardiovascular ettects and stroke
4. Abuse potential
4. What're antihistamines for? (Benadryl)
Answer: Allergic rhinitis
,5. What happens when histamine is released?
Answer: It dilates small blood vessels and increase capillary permeability
6. What doesn't antihistamines reduce?
Answer: Nasal congestion
7. Antihistamines are most effective when?
Answer: -Taken regularly
-Take even when symptoms are absent
8. Second generation antihistamine is known as what? What AE does it not
cause?
Answer: -Zyrtec
-Sedation
9. Antihistamines: Adverse Effects
Answer: Anticholinergic (drying) ettects, most common Dry mouth
Diflculty urinating
Constipation
Changes in vision
Drowsiness
Mild drowsiness to deep sleep
,10. Intranasal antihistamines are indicated for what in adults and children 12yo
and older?
Answer: Allergic rhinits
11. AE of intranasal antihistamines (azelastine and olopatadin)
Answer: -Nose bleeds
-Anticholinergic ettects
-Unpleasant taste
-Sedation
12. Opioid antitussives include
Answer: -codeine and hydrocodone
13. Non-opioid antitussives include
Answer: -dextromethorphan
-diphenhydramine
-benzonatate
14. What is the most common use of cough medications?
Answer: For the suppression of a non-productive cough associated with the common cold and other
upper respiratory infections
15. This medication acts on cough center in the medulla and it decreases sensi-
, tivity of cough receptors and interrupts cough impulse transmission
Answer: Dextromethor- phan (tessalon perles)
16. AE of dextromethorphan
Answer: Nausea, vomiting, constipation, sedation, drowsiness, confusion, dizzy and nervousness
17. This non-narcotic antitussive actually provides low local anesthetic effects on
the anesthetized stretch, receptors in the respiratory passage and lungs
Answer: Ben- zonatate
18. When you think tessalon perles, think of what?
Answer: Anesthetic
19. What is the first choice and most effective treatment prevention of rhinitis?-
Answer: Intranasal glucocorticoids
20. AE of intranasal glucocorticoids
Answer: Drying of nasal mucosa, Burning or itching sensation, Sore throat, Epistaxis, Headache
21. What do you give intranasal glucocorticoids for?
Answer: Congestion, rhinorrhea, sneezing and nasal itching
22. This is a rare but serious AE that can occur from glucocorticoids
Answer: Adrenal suppres- sion and slowing of linear pediatric growth