2026 UPDATED QUESTIONS DOWNLOAD
ATI Med-Surg Endocrine Exam 2025/2026 | 350
Questions with Italicized Rationales | High-Yield
Prep & Study Guide
This comprehensive study guide features 350 high-yield multiple-choice
questions specifically designed for the ATI Medical-Surgical Endocrine Exam. Each question
includes a detailed rationale in italics, helping you master complex concepts like DKA,
SIADH, and adrenal disorders through active learning. It is perfectly formatted for quick review
and guaranteed to strengthen your clinical judgment for your next nursing school assessment.
1.
A nurse is caring for a patient with hyperthyroidism. Which assessment finding is expected?
A. Weight gain
B. Cold intolerance
C. Heat intolerance
D. Bradycardia
Answer: C. Heat intolerance
Rationale: Hyperthyroidism increases metabolic rate, leading to heat intolerance.
2.
Which medication is commonly used to treat hypothyroidism?
A. Methimazole
B. Levothyroxine
C. Propranolol
D. Prednisone
Answer: B. Levothyroxine
Rationale: Levothyroxine replaces deficient thyroid hormone.
,2026 UPDATED QUESTIONS DOWNLOAD
3.
A patient with diabetes mellitus has a blood glucose of 45 mg/dL. What is the priority
intervention?
A. Administer insulin
B. Give 15 g of fast-acting carbohydrate
C. Restrict fluids
D. Encourage exercise
Answer: B. Give 15 g of fast-acting carbohydrate
Rationale: Hypoglycemia must be treated immediately with glucose.
4.
Which assessment finding is associated with Cushing’s syndrome?
A. Weight loss
B. Moon face
C. Hypotension
D. Hyperkalemia
Answer: B. Moon face
Rationale: Cushing’s causes fat redistribution leading to a rounded face.
5.
Which laboratory value is expected in Addison’s disease?
A. Hypernatremia
B. Hyperglycemia
C. Hyponatremia
D. Hypercalcemia
Answer: C. Hyponatremia
Rationale: Addison’s disease leads to sodium loss due to low aldosterone.
6.
A patient with diabetes insipidus is at risk for which imbalance?
,2026 UPDATED QUESTIONS DOWNLOAD
A. Fluid overload
B. Dehydration
C. Hypoglycemia
D. Hyperkalemia
Answer: B. Dehydration
Rationale: Excessive urine output leads to fluid loss.
7.
Which medication is used to treat hyperthyroidism?
A. Levothyroxine
B. Methimazole
C. Insulin
D. Glucagon
Answer: B. Methimazole
Rationale: Methimazole reduces thyroid hormone production.
8.
A patient is experiencing thyroid storm. What is the priority nursing action?
A. Provide a warm blanket
B. Administer antithyroid medication
C. Encourage fluids only
D. Monitor urine output
Answer: B. Administer antithyroid medication
Rationale: Thyroid storm is life-threatening and requires immediate treatment.
9.
Which symptom is associated with hypothyroidism?
A. Weight loss
B. Tachycardia
C. Cold intolerance
D. Diarrhea
, 2026 UPDATED QUESTIONS DOWNLOAD
Answer: C. Cold intolerance
Rationale: Reduced metabolism leads to intolerance to cold.
10.
Which hormone is produced by the pancreas to lower blood glucose?
A. Glucagon
B. Insulin
C. Cortisol
D. Aldosterone
Answer: B. Insulin
Rationale: Insulin promotes glucose uptake by cells.
11.
A patient with diabetic ketoacidosis (DKA) is expected to have:
A. Low blood glucose
B. Metabolic alkalosis
C. Ketones in urine
D. Bradycardia
Answer: C. Ketones in urine
Rationale: DKA results in ketone production due to fat breakdown.
12.
Which electrolyte imbalance is common in DKA?
A. Hypokalemia
B. Hyperkalemia
C. Hypercalcemia
D. Hyponatremia only
Answer: B. Hyperkalemia
Rationale: Potassium shifts out of cells during acidosis.
ATI Med-Surg Endocrine Exam 2025/2026 | 350
Questions with Italicized Rationales | High-Yield
Prep & Study Guide
This comprehensive study guide features 350 high-yield multiple-choice
questions specifically designed for the ATI Medical-Surgical Endocrine Exam. Each question
includes a detailed rationale in italics, helping you master complex concepts like DKA,
SIADH, and adrenal disorders through active learning. It is perfectly formatted for quick review
and guaranteed to strengthen your clinical judgment for your next nursing school assessment.
1.
A nurse is caring for a patient with hyperthyroidism. Which assessment finding is expected?
A. Weight gain
B. Cold intolerance
C. Heat intolerance
D. Bradycardia
Answer: C. Heat intolerance
Rationale: Hyperthyroidism increases metabolic rate, leading to heat intolerance.
2.
Which medication is commonly used to treat hypothyroidism?
A. Methimazole
B. Levothyroxine
C. Propranolol
D. Prednisone
Answer: B. Levothyroxine
Rationale: Levothyroxine replaces deficient thyroid hormone.
,2026 UPDATED QUESTIONS DOWNLOAD
3.
A patient with diabetes mellitus has a blood glucose of 45 mg/dL. What is the priority
intervention?
A. Administer insulin
B. Give 15 g of fast-acting carbohydrate
C. Restrict fluids
D. Encourage exercise
Answer: B. Give 15 g of fast-acting carbohydrate
Rationale: Hypoglycemia must be treated immediately with glucose.
4.
Which assessment finding is associated with Cushing’s syndrome?
A. Weight loss
B. Moon face
C. Hypotension
D. Hyperkalemia
Answer: B. Moon face
Rationale: Cushing’s causes fat redistribution leading to a rounded face.
5.
Which laboratory value is expected in Addison’s disease?
A. Hypernatremia
B. Hyperglycemia
C. Hyponatremia
D. Hypercalcemia
Answer: C. Hyponatremia
Rationale: Addison’s disease leads to sodium loss due to low aldosterone.
6.
A patient with diabetes insipidus is at risk for which imbalance?
,2026 UPDATED QUESTIONS DOWNLOAD
A. Fluid overload
B. Dehydration
C. Hypoglycemia
D. Hyperkalemia
Answer: B. Dehydration
Rationale: Excessive urine output leads to fluid loss.
7.
Which medication is used to treat hyperthyroidism?
A. Levothyroxine
B. Methimazole
C. Insulin
D. Glucagon
Answer: B. Methimazole
Rationale: Methimazole reduces thyroid hormone production.
8.
A patient is experiencing thyroid storm. What is the priority nursing action?
A. Provide a warm blanket
B. Administer antithyroid medication
C. Encourage fluids only
D. Monitor urine output
Answer: B. Administer antithyroid medication
Rationale: Thyroid storm is life-threatening and requires immediate treatment.
9.
Which symptom is associated with hypothyroidism?
A. Weight loss
B. Tachycardia
C. Cold intolerance
D. Diarrhea
, 2026 UPDATED QUESTIONS DOWNLOAD
Answer: C. Cold intolerance
Rationale: Reduced metabolism leads to intolerance to cold.
10.
Which hormone is produced by the pancreas to lower blood glucose?
A. Glucagon
B. Insulin
C. Cortisol
D. Aldosterone
Answer: B. Insulin
Rationale: Insulin promotes glucose uptake by cells.
11.
A patient with diabetic ketoacidosis (DKA) is expected to have:
A. Low blood glucose
B. Metabolic alkalosis
C. Ketones in urine
D. Bradycardia
Answer: C. Ketones in urine
Rationale: DKA results in ketone production due to fat breakdown.
12.
Which electrolyte imbalance is common in DKA?
A. Hypokalemia
B. Hyperkalemia
C. Hypercalcemia
D. Hyponatremia only
Answer: B. Hyperkalemia
Rationale: Potassium shifts out of cells during acidosis.
