NR 406B Final Exam: Pharmacology II V1 Updated and
Latest Questions and Correct Answers - Regis University
1. A patient is prescribed Lisinopril for hypertension. Which side effect is most specifically
associated with the inhibition of bradykinin breakdown by this medication?
A. Dry, nonproductive cough
B. Peripheral edema
C. Hypokalemia
D. Tachycardia
Correct Answer: A
Explanation: ACE inhibitors like Lisinopril prevent the breakdown of bradykinin, which can accumulate
in the lungs and cause a persistent dry cough in some patients. This comprehensive pharmacology exam
is tailored for the NR 406B course at Regis University. It encompasses fifty medium-difficulty questions
covering diverse medication classes. The content focuses on nursing responsibilities, side effects, and
therapeutic monitoring. Each question includes four distinct options to challenge the student’s clinical
reasoning. Explanations provide deep insights into why the correct answer is the priority. Topics range
from cardiovascular drugs like ACE inhibitors to complex psychotropic medications. Safety is emphasized
through questions on antidotes, peak/trough levels, and contraindications. The random distribution of
answers ensures a balanced and fair assessment environment. This tool serves as a rigorous preparation
tool for the final examination. All information is presented in a valid JSON format to ensure seamless
integration.
2. A nurse is monitoring a patient on Warfarin therapy. What is the standard therapeutic INR
range for a patient with atrial fibrillation?
A. 0.5 to 1.5
B. 5.0 to 6.0
C. 3.5 to 4.5
D. 2.0 to 3.0
Correct Answer: D
Explanation: For most conditions like atrial fibrillation or DVT prophylaxis, the target INR range is 2.0 to
3.0. Higher ranges may be required for mechanical heart valves.
,3. A patient taking Digoxin reports seeing yellow-green halos around lights. What is the
nurse’s priority action?
A. Assess the patient’s serum potassium and Digoxin levels
B. Document the finding as a normal side effect
C. Increase the next dose of Digoxin
D. Administer an antiemetic immediately
Correct Answer: A
Explanation: Visual disturbances, such as yellow-green halos, are classic signs of Digoxin toxicity, which
can be precipitated by hypokalemia.
4. When should a patient be instructed to take their daily dose of Levothyroxine?
A. At bedtime with a snack
B. In the morning, 30 to 60 minutes before breakfast
C. With the largest meal of the day
D. Immediately after a high-fiber lunch
Correct Answer: B
Explanation: Levothyroxine should be taken on an empty stomach in the morning to maximize
absorption and prevent interference from food or other medications.
5. A patient scheduled for a CT scan with IV contrast takes Metformin daily. What instruction
must the nurse provide?
A. Double the dose on the day of the procedure
B. Metformin has no interaction with contrast dye
C. Take Metformin with the contrast dye
D. Hold Metformin 48 hours before and after the scan
Correct Answer: D
Explanation: Metformin must be held before and after contrast dye administration to prevent the risk of
lactic acidosis and acute renal failure.
, 6. Which electrolyte imbalance is a patient at risk for when taking Spironolactone?
A. Hypokalemia
B. Hypocalcemia
C. Hyponatremia
D. Hyperkalemia
Correct Answer: D
Explanation: Spironolactone is a potassium-sparing diuretic that inhibits aldosterone, leading to the
retention of potassium.
7. What laboratory value is used to monitor the therapeutic effectiveness of Heparin
administered intravenously?
A. Prothrombin Time (PT)
B. International Normalized Ratio (INR)
C. Activated Partial Thromboplastin Time (aPTT)
D. Platelet count
Correct Answer: C
Explanation: aPTT is the standard test for monitoring unfractionated heparin therapy to ensure the
patient is within the therapeutic range.
8. A patient is using sublingual Nitroglycerin for chest pain. Which common side effect
should the nurse include in the teaching?
A. Hypertension
B. Bradycardia
C. Headache
D. Constipation
Correct Answer: C
Explanation: Nitroglycerin causes significant vasodilation, which frequently results in a throbbing
headache and orthostatic hypotension.
Latest Questions and Correct Answers - Regis University
1. A patient is prescribed Lisinopril for hypertension. Which side effect is most specifically
associated with the inhibition of bradykinin breakdown by this medication?
A. Dry, nonproductive cough
B. Peripheral edema
C. Hypokalemia
D. Tachycardia
Correct Answer: A
Explanation: ACE inhibitors like Lisinopril prevent the breakdown of bradykinin, which can accumulate
in the lungs and cause a persistent dry cough in some patients. This comprehensive pharmacology exam
is tailored for the NR 406B course at Regis University. It encompasses fifty medium-difficulty questions
covering diverse medication classes. The content focuses on nursing responsibilities, side effects, and
therapeutic monitoring. Each question includes four distinct options to challenge the student’s clinical
reasoning. Explanations provide deep insights into why the correct answer is the priority. Topics range
from cardiovascular drugs like ACE inhibitors to complex psychotropic medications. Safety is emphasized
through questions on antidotes, peak/trough levels, and contraindications. The random distribution of
answers ensures a balanced and fair assessment environment. This tool serves as a rigorous preparation
tool for the final examination. All information is presented in a valid JSON format to ensure seamless
integration.
2. A nurse is monitoring a patient on Warfarin therapy. What is the standard therapeutic INR
range for a patient with atrial fibrillation?
A. 0.5 to 1.5
B. 5.0 to 6.0
C. 3.5 to 4.5
D. 2.0 to 3.0
Correct Answer: D
Explanation: For most conditions like atrial fibrillation or DVT prophylaxis, the target INR range is 2.0 to
3.0. Higher ranges may be required for mechanical heart valves.
,3. A patient taking Digoxin reports seeing yellow-green halos around lights. What is the
nurse’s priority action?
A. Assess the patient’s serum potassium and Digoxin levels
B. Document the finding as a normal side effect
C. Increase the next dose of Digoxin
D. Administer an antiemetic immediately
Correct Answer: A
Explanation: Visual disturbances, such as yellow-green halos, are classic signs of Digoxin toxicity, which
can be precipitated by hypokalemia.
4. When should a patient be instructed to take their daily dose of Levothyroxine?
A. At bedtime with a snack
B. In the morning, 30 to 60 minutes before breakfast
C. With the largest meal of the day
D. Immediately after a high-fiber lunch
Correct Answer: B
Explanation: Levothyroxine should be taken on an empty stomach in the morning to maximize
absorption and prevent interference from food or other medications.
5. A patient scheduled for a CT scan with IV contrast takes Metformin daily. What instruction
must the nurse provide?
A. Double the dose on the day of the procedure
B. Metformin has no interaction with contrast dye
C. Take Metformin with the contrast dye
D. Hold Metformin 48 hours before and after the scan
Correct Answer: D
Explanation: Metformin must be held before and after contrast dye administration to prevent the risk of
lactic acidosis and acute renal failure.
, 6. Which electrolyte imbalance is a patient at risk for when taking Spironolactone?
A. Hypokalemia
B. Hypocalcemia
C. Hyponatremia
D. Hyperkalemia
Correct Answer: D
Explanation: Spironolactone is a potassium-sparing diuretic that inhibits aldosterone, leading to the
retention of potassium.
7. What laboratory value is used to monitor the therapeutic effectiveness of Heparin
administered intravenously?
A. Prothrombin Time (PT)
B. International Normalized Ratio (INR)
C. Activated Partial Thromboplastin Time (aPTT)
D. Platelet count
Correct Answer: C
Explanation: aPTT is the standard test for monitoring unfractionated heparin therapy to ensure the
patient is within the therapeutic range.
8. A patient is using sublingual Nitroglycerin for chest pain. Which common side effect
should the nurse include in the teaching?
A. Hypertension
B. Bradycardia
C. Headache
D. Constipation
Correct Answer: C
Explanation: Nitroglycerin causes significant vasodilation, which frequently results in a throbbing
headache and orthostatic hypotension.
