Hematology Final Exam, MCQ
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1. A young adult presents with fatigue and pal- Iron deficiency anemia
lor. Laboratory evaluation reveals microcytic,
hypochromic anemia. What is the most likely
cause?
2. A 35-year-old woman presents with fatigue and Decreased oxygen-carrying ca-
pallor. Laboratory tests reveal low hemoglobin and pacity of blood
hematocrit. Which of the following is the most
likely immediate effect of anemia on her body?
3. Which of the following best describes a microcytic Iron deficiency anemia
anemia due to impaired hemoglobin synthesis?
4. A 30-year-old woman presents with fatigue and Iron deficiency
pallor. Laboratory tests show low hemoglobin, low
mean corpuscular volume (MCV), and low serum
ferritin. Which of the following is the most likely
cause of her anemia?
5. A 50-year-old woman presents with glossitis and Vitamin B12
numbness in her hands. Laboratory results show
macrocytic anemia and hypersegmented neu-
trophils. Which deficiency is most likely responsi-
ble?
6. Which initial laboratory test is most useful to dis- Mean corpuscular volume
tinguish between microcytic and macrocytic ane- (MCV)
mia?
7. Which laboratory value provides a direct indication Hemoglobin
of a patient's oxygen-carrying capacity and is com-
monly used to help confirm anemia?
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Hematology Final Exam, MCQ
Study online at https://quizlet.com/_igetqw
8. Which laboratory test is most useful for assessing Reticulocyte count
bone marrow response in a patient with anemia?
9. Which therapy is most appropriate for a patient Intramuscular vitamin B12 in-
with anemia due to vitamin B12 deficiency? jections
10. Which patient is most likely to benefit from oral A patient with iron-deficiency
iron supplementation therapy for anemia? anemia due to heavy menstrual
bleeding
11. In which situation is immediate blood transfusion Severe anemia causing cardiac
most appropriate for anemia management? instability and acute symptoms
12. A teen comes in with frequent nosebleeds, espe- Prothrombin time (PT) and ac-
cially after minor injuries. There is a history of pro- tivated partial thromboplastin
longed bleeding after dental procedures. Which is time (aPTT)
the most appropriate test to screen for common
bleeding disorders?
13. Which of the following BEST categorizes bleeding Inherited vs acquired causes
disorders in clinical practice?
14. Which of the following clinical findings is most Immediate, superficial mucocu-
commonly associated with platelet disorders in a taneous bleeding
patient presenting with bleeding?
15. In clinical practice, which of the following is con- von Willebrand disease
sidered the most frequent inherited bleeding dis-
order in the general population?
16. A patient with severe sepsis develops bleeding Treat underlying cause and pro-
from IV sites, low platelets, elevated PT and aPTT, vide supportive care
and low fibrinogen. What is the initial step in man-
agement?
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Hematology Final Exam, MCQ
Study online at https://quizlet.com/_igetqw
17. A 10-year-old boy with a history of easy bruising Recombinant factor VIII
and joint swelling after minor trauma is found to
have a low factor VIII level. What is the mainstay
of treatment during acute bleeding episodes?
18. A 24-year-old woman presents with frequent nose- Desmopressin (DDAVP)
bleeds and heavy menstrual periods. Laboratory
tests show a prolonged bleeding time and de-
creased ristocetin cofactor activity. Which treat-
ment is most appropriate to stop acute bleeding
in this patient?
19. Which laboratory test is most useful in distinguish- Prothrombin time (PT) and ac-
ing between a platelet disorder and a coagula- tivated partial thromboplastin
tion factor deficiency in a patient with unexplained time (aPTT)
bleeding?
20. A prolonged activated partial thromboplastin time Intrinsic factor deficiency
(aPTT) primarily suggests an abnormality in which
part of the coagulation cascade?
21. A 55-year-old man is found to have persistent fa- To minimize risk of life-threat-
tigue and frequent infections. His blood smear ening infections
shows abnormal white blood cells. Why is prompt
diagnosis and treatment of common leukemias
important in clinical practice?
22. First-line treatment for acute lymphoblastic Combination chemotherapy
leukemia typically includes which of the following?
23. Which describes the primary goal of chemothera-
py in the treatment of acute leukemia?
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