sketch and interpret MO diagram
lecture 1 introduction: bioinorganic paradox definition
atomic structure & diatomic molecules (ch 1,2)
dose determines if the toxic compound is indeed toxic
metal ions: ligand binding, catalysis, signaling, regulation, sensing, defense, structural
support
, bio-inorganic chemistry: naturally occurring inorganic elements in biology and introduction of
metals into biological systems (probes & drugs)
functions in metalloproteins
- dioxygen transport (Fe(II/III))
- electron transfer (Cu(I/II))
- structural roles (Zn2+)
nuclei stability is expressed in terms of binding energy: difference in energy between nucleus
and same numbers of individual protons + neutrons (related to difference in mass (nucleons
- nucleus) by E=mc^2)
- positive binding energy > nucleus with lower/more favorable energy than constituent
nucleons
fusion: results new nucleus with larger nuclear binding energy (excess energy released)
fission: division/splitting of nuclei into lighter products (binding energy released)
synthetic element: doesn’t naturally occur on earth but is artificially generated by nuclear
reactions
constructive interference yields enhanced amplitude
destructive interference yields reduced amplitude
n: principal quantum number, specifies energy of bound electron, indicates size orbital
l: orbital angular momentum quantum number, labels magnitude of orbital angular
momentum, indicates angular shape of orbital
m_l: magnetic quantum number, labels orientation of orbital angular momentum, indicates
orientation of lobes
eV: amount of gained kinetic energy by electron as it accelerates through potential of 1 V
- 1 eV ≈ 100 kJ/mol
lecture 1 introduction: bioinorganic paradox definition
atomic structure & diatomic molecules (ch 1,2)
dose determines if the toxic compound is indeed toxic
metal ions: ligand binding, catalysis, signaling, regulation, sensing, defense, structural
support
, bio-inorganic chemistry: naturally occurring inorganic elements in biology and introduction of
metals into biological systems (probes & drugs)
functions in metalloproteins
- dioxygen transport (Fe(II/III))
- electron transfer (Cu(I/II))
- structural roles (Zn2+)
nuclei stability is expressed in terms of binding energy: difference in energy between nucleus
and same numbers of individual protons + neutrons (related to difference in mass (nucleons
- nucleus) by E=mc^2)
- positive binding energy > nucleus with lower/more favorable energy than constituent
nucleons
fusion: results new nucleus with larger nuclear binding energy (excess energy released)
fission: division/splitting of nuclei into lighter products (binding energy released)
synthetic element: doesn’t naturally occur on earth but is artificially generated by nuclear
reactions
constructive interference yields enhanced amplitude
destructive interference yields reduced amplitude
n: principal quantum number, specifies energy of bound electron, indicates size orbital
l: orbital angular momentum quantum number, labels magnitude of orbital angular
momentum, indicates angular shape of orbital
m_l: magnetic quantum number, labels orientation of orbital angular momentum, indicates
orientation of lobes
eV: amount of gained kinetic energy by electron as it accelerates through potential of 1 V
- 1 eV ≈ 100 kJ/mol
