Page | 1
APEA 3P HIGH STAKES EXAM STUDY
GUIDE 2026 QUESTIONS AND
ANSWERS | A+ GRADED | WITH
EXPERT SOLUTIONS
What would cause decrease in Digoxin levels? - ANSWER-
Antacids
Taking Pyridium for UTI, what can Pyridium cause? - ANSWER-
Hemolytic Anemia
What can PCOS result in? - ANSWER-Increased insulin levels
(Hyperinsulinemia), Androgens, Hirsutism
What are the anti-hypertensives used in pregnancy? -
ANSWER-Methyldopa (Alpha-2-Agonist), Labetalol, Nifedipine,
Hydralazine
What is a characteristic of Placenta Previa? - ANSWER-
Painless, red bleeding
, Page | 2
What is a chacteristic of Rheumatoid Arthritis? - ANSWER-
Tender, warm, swollen joints
Medications that can cause ototoxicity? - ANSWER-
Aminoglycosides, loop diuretics, NSAIDs, antihistamines, nasal
decongestants
What is the treatment time for enterobiasis? - ANSWER-2
weeks
What does MCV lab value measure? - ANSWER-Mean
Corpuscular Volume helps diagnose different types of anemia
such as B12 & Folate (Macrocytic) and Fe anemia (Microcytic)
Rhogam is given at how many week gestation? - ANSWER-27-
28 weeks
, Page | 3
What are Janeway lesions and what do they indicate? -
ANSWER-They are irregular, non-tender hemorrhagic macules
located on the hands and feet. Seen in Infective Endocarditis
What are Osler's Nodes and what do they indicate? -
ANSWER-They are split pea-sized, erythematous, tender
nodules located on the pads of the fingers and toes. Seen in
Infective Endocarditis
What is the recommendation for Warfarin management when a
patient misses a dose? - ANSWER-If within 12 hours of the
dose time, take it. If over 12 hours patient will need a INR
redraw
What do we need to know about ACEs and ARBs? - ANSWER-
A dry hacking cough is a common side effect of ACEs and will
go away within a week after discontinuing. ACEs & ARBs are
indicated for patients with DM, CKD, and HTN. Not
recommended as 1st line agent with African Americans & can
cause angioedema.
Contraindications for Hydrochlorothiazide - ANSWER-Sulfa
allergy, PCN hypersensitivity, Asthma, Gout
, Page | 4
Systolic Murmurs (Benign) - ANSWER-MR = Mitral Regurge
(SOB/Fatigue HF)
Peyton Manning = Physiologic Murmur (Asymptomatic)
AS = Aortic Stenosis (Angina, Syncope HF)
MVP = Mitral Valve Prolapse ("Click", Women 14-30,
Palpitations, Chest Pain
Diastolic Murmurs (Abnormal) - ANSWER-AR = Aortic
Regurgitation (Angina, HF, Dizziness, Chest Pain)
MS = Mitral Stenosis (Dyspnea, AFib)
What does S1 indicate? - ANSWER-S1 Closure of the
Atrioventricular Valves (Mitral & Tricuspid Valves)
What does S2 indicate? - ANSWER-S2 Closure of the
Semilunar Valves (Aortic & Pulmonic Valves)
S3 is often heard in? - ANSWER-CHF, possibly normal for
athletic adolescents
APEA 3P HIGH STAKES EXAM STUDY
GUIDE 2026 QUESTIONS AND
ANSWERS | A+ GRADED | WITH
EXPERT SOLUTIONS
What would cause decrease in Digoxin levels? - ANSWER-
Antacids
Taking Pyridium for UTI, what can Pyridium cause? - ANSWER-
Hemolytic Anemia
What can PCOS result in? - ANSWER-Increased insulin levels
(Hyperinsulinemia), Androgens, Hirsutism
What are the anti-hypertensives used in pregnancy? -
ANSWER-Methyldopa (Alpha-2-Agonist), Labetalol, Nifedipine,
Hydralazine
What is a characteristic of Placenta Previa? - ANSWER-
Painless, red bleeding
, Page | 2
What is a chacteristic of Rheumatoid Arthritis? - ANSWER-
Tender, warm, swollen joints
Medications that can cause ototoxicity? - ANSWER-
Aminoglycosides, loop diuretics, NSAIDs, antihistamines, nasal
decongestants
What is the treatment time for enterobiasis? - ANSWER-2
weeks
What does MCV lab value measure? - ANSWER-Mean
Corpuscular Volume helps diagnose different types of anemia
such as B12 & Folate (Macrocytic) and Fe anemia (Microcytic)
Rhogam is given at how many week gestation? - ANSWER-27-
28 weeks
, Page | 3
What are Janeway lesions and what do they indicate? -
ANSWER-They are irregular, non-tender hemorrhagic macules
located on the hands and feet. Seen in Infective Endocarditis
What are Osler's Nodes and what do they indicate? -
ANSWER-They are split pea-sized, erythematous, tender
nodules located on the pads of the fingers and toes. Seen in
Infective Endocarditis
What is the recommendation for Warfarin management when a
patient misses a dose? - ANSWER-If within 12 hours of the
dose time, take it. If over 12 hours patient will need a INR
redraw
What do we need to know about ACEs and ARBs? - ANSWER-
A dry hacking cough is a common side effect of ACEs and will
go away within a week after discontinuing. ACEs & ARBs are
indicated for patients with DM, CKD, and HTN. Not
recommended as 1st line agent with African Americans & can
cause angioedema.
Contraindications for Hydrochlorothiazide - ANSWER-Sulfa
allergy, PCN hypersensitivity, Asthma, Gout
, Page | 4
Systolic Murmurs (Benign) - ANSWER-MR = Mitral Regurge
(SOB/Fatigue HF)
Peyton Manning = Physiologic Murmur (Asymptomatic)
AS = Aortic Stenosis (Angina, Syncope HF)
MVP = Mitral Valve Prolapse ("Click", Women 14-30,
Palpitations, Chest Pain
Diastolic Murmurs (Abnormal) - ANSWER-AR = Aortic
Regurgitation (Angina, HF, Dizziness, Chest Pain)
MS = Mitral Stenosis (Dyspnea, AFib)
What does S1 indicate? - ANSWER-S1 Closure of the
Atrioventricular Valves (Mitral & Tricuspid Valves)
What does S2 indicate? - ANSWER-S2 Closure of the
Semilunar Valves (Aortic & Pulmonic Valves)
S3 is often heard in? - ANSWER-CHF, possibly normal for
athletic adolescents
