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Lecture notes Cell recognition and the immune system New A-Level Biology for AQA: Year 1 & 2 Student Book with On

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This document provides notes on a level year 12 aqa’s cell recognition and immunity topic coves the a level text book and the cgp book in a simple yet understandable way to get you the marks needed

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,
,Background and introduction
Antibodies: are proteins that binds to the antigen as part of the immune response

The immune system is our bodys way of detecting and dealing with foreign antigen. In order

to do this the way of recognising what is foreign is called self/non-self recognition. When a

non self antigen is detected it will trigger an immune response which may involve the

production of antibodies. The immune system can also recognise when our own cells become

a threat: when infected with a virus or when turned into a tumour itself which is known as self

recognition




What is immunity?

Is the ability of an organism to resist infection from invading disease causing microorganisms

(Pathogens). This may involve an immune response, which is the organism recognising and

responding to antigens and destroying substances carrying non-self antigens through the

activation of lymphocytes




·

, Quick recap
1.

Pathogens

Microbes that cause disease (bacteria, viruses, fungi, protozoa).

2.

Antigens

Proteins on cell surfaces that trigger an immune response.

Pathogens, foreign cells, or abnormal body cells have them.

3.

White Blood Cells (WBCs)

Phagocytes – engulf and digest pathogens (non-speci c).

Lymphocytes – speci c response:

B cells → make antibodies (humoral immunity).

T cells → kill infected cells & help B cells (cell-mediated immunity).





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