BIOD 210 Exam 6 | Questions and Answers Latest
Updated (Graded A+)- Portage Learning
1. An alteration to the chromosome that results in a change to the total
number of chromosomes, deletions or additions to the chromosome,
or even complete rearrangement of chromosomal segments is called a
chromosomal
Aberration
2. True or False: A chromosomal ablation is an alteration to the
chromosome that results in a change to the total number of
chromosomes, deletions or additions to the chromosome, or even
complete rearrangement of chromosomal segments.
False
3. True or false: A chromosomal aberration is an alteration to the
chromosome that results in a change to the total number of
chromosomes, deletions or additions to the chromosome, or even
complete rearrangement of chromosomal segments.
True
4. True or False: Sex chromosomes can occur in pairs but also exist with
no phenotypic sequence
False
5. True or False: Sex chromosomes are the only exception to the rule
that chromosomes occur in pairs.
True
6. True or False: Sex chromosomes occur in identical pairs.
False
7. True or False: Trisomy and monosomy in autosomal chromosomes are
generally not tolerated in animals or plants
False
8. True or False: Trisomy and monosomy in autosomal chromosomes are
generally tolerated better in plants than in animals.
True
9. What is the only trisomy disorder in which individuals routinely live
longer than one year? The incidence of this disorder seems to
increase with an increased age in which parent.
Down Syndrome; incidence seems to increase with maternal age.
10. Is Down syndrome considered monosomy or trisomy? Does it
incidence increase or decrease with maternal age?
Down syndrome is a trisomy disorder, the incidence of which seems to
increase with maternal age
11. True or False: Individuals that are afflicted with Down syndrome
typically exhibit most, if not all, of the stereotypical characteristics of
, the disorder.
False
12. True or False: Individuals that are afflicted with Down syndrome
typically exhibit only a subset of the stereotypical characteristics of
the disorder
True
13. True or False: The region of the chromosome 20 that is thought
to be responsible for the phenotype for Down syndrome is the DSCR
False
14. The region of the chromosome 21 that is thought to be typically
responsible for the phenotype of Down syndrome is the
DSCR
15. Why do researchers think that individuals with Down Syndrome
are protected from cancers that cause solid tumors
The DSCR region that is responsible for the phenotype of Down
syndrome holds a gene called DSCR1, which encodes for a protein
that blocks VEGF (vascular epithelial growth factor). VEGF stimulates
the growth of blood vessels, which is extremely important for the
vasculature of tumor cells. By blocking VEGF, tumor cells cannot
develop the vasculature necessary for the support of tumor growth.
16. Noninvasive prenatal testing (NIPT) is a test that gives
an estimated risk of the fetus having .
screening, aneuploidy
17. The most recent and non-invasive genetic test to determine
whether a mother is carrying a baby at risk one of the common
trisomies is called . This process allows the mother to donate a
blood sample to detect .
NIPT; cell-free fetal DNA
18. The most recent and non-invasive genetic test to determine
whether a mother is carrying a baby at risk for Down syndrome (or
any genetic disorder) is called . This process allows the
mother to donate a sample from the blood to establish a for the
risk of genetic disorders.
NIPT; karyotype
19. In a few sentences, what are the current thoughts on why the
incidence of Down syndrome increases drastically after age 40 in a
mother?
The current though is that the eggs undergo meiosis I in a female
fetus, and then are arrested until the female goes through puberty. At
that point, with each passing month, the eggs continue to age until
Updated (Graded A+)- Portage Learning
1. An alteration to the chromosome that results in a change to the total
number of chromosomes, deletions or additions to the chromosome,
or even complete rearrangement of chromosomal segments is called a
chromosomal
Aberration
2. True or False: A chromosomal ablation is an alteration to the
chromosome that results in a change to the total number of
chromosomes, deletions or additions to the chromosome, or even
complete rearrangement of chromosomal segments.
False
3. True or false: A chromosomal aberration is an alteration to the
chromosome that results in a change to the total number of
chromosomes, deletions or additions to the chromosome, or even
complete rearrangement of chromosomal segments.
True
4. True or False: Sex chromosomes can occur in pairs but also exist with
no phenotypic sequence
False
5. True or False: Sex chromosomes are the only exception to the rule
that chromosomes occur in pairs.
True
6. True or False: Sex chromosomes occur in identical pairs.
False
7. True or False: Trisomy and monosomy in autosomal chromosomes are
generally not tolerated in animals or plants
False
8. True or False: Trisomy and monosomy in autosomal chromosomes are
generally tolerated better in plants than in animals.
True
9. What is the only trisomy disorder in which individuals routinely live
longer than one year? The incidence of this disorder seems to
increase with an increased age in which parent.
Down Syndrome; incidence seems to increase with maternal age.
10. Is Down syndrome considered monosomy or trisomy? Does it
incidence increase or decrease with maternal age?
Down syndrome is a trisomy disorder, the incidence of which seems to
increase with maternal age
11. True or False: Individuals that are afflicted with Down syndrome
typically exhibit most, if not all, of the stereotypical characteristics of
, the disorder.
False
12. True or False: Individuals that are afflicted with Down syndrome
typically exhibit only a subset of the stereotypical characteristics of
the disorder
True
13. True or False: The region of the chromosome 20 that is thought
to be responsible for the phenotype for Down syndrome is the DSCR
False
14. The region of the chromosome 21 that is thought to be typically
responsible for the phenotype of Down syndrome is the
DSCR
15. Why do researchers think that individuals with Down Syndrome
are protected from cancers that cause solid tumors
The DSCR region that is responsible for the phenotype of Down
syndrome holds a gene called DSCR1, which encodes for a protein
that blocks VEGF (vascular epithelial growth factor). VEGF stimulates
the growth of blood vessels, which is extremely important for the
vasculature of tumor cells. By blocking VEGF, tumor cells cannot
develop the vasculature necessary for the support of tumor growth.
16. Noninvasive prenatal testing (NIPT) is a test that gives
an estimated risk of the fetus having .
screening, aneuploidy
17. The most recent and non-invasive genetic test to determine
whether a mother is carrying a baby at risk one of the common
trisomies is called . This process allows the mother to donate a
blood sample to detect .
NIPT; cell-free fetal DNA
18. The most recent and non-invasive genetic test to determine
whether a mother is carrying a baby at risk for Down syndrome (or
any genetic disorder) is called . This process allows the
mother to donate a sample from the blood to establish a for the
risk of genetic disorders.
NIPT; karyotype
19. In a few sentences, what are the current thoughts on why the
incidence of Down syndrome increases drastically after age 40 in a
mother?
The current though is that the eggs undergo meiosis I in a female
fetus, and then are arrested until the female goes through puberty. At
that point, with each passing month, the eggs continue to age until
