NR566/NR 566 week 1 Exam TEST FINAL EXAM AND
PRACTICE EXAM 20262027 BANK 2 VERSIONS QUESTIONS
WITH DETAILED VERIFIED ANSWERS EXAM QUESTIONS
WILL COME FROM HERE (100% CORRECT ANSWERS A+
GRADED
What are the major antibiotic drug classes - ANSWERS--Beta-lactams:
penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin
What is the primary goal of antibiotic therapy - ANSWERS--kill bacteria
without harming host tissue
Bactericidal antibiotics - ANSWERS--directly kill bacteria
Bacteriostatic antibiotics - ANSWERS--Antibiotics that do not actually
kill bacteria but rather inhibit bacterial proliferation while the hosts
immune system does the killing
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Which antibiotics are preferred for immunocompromised patients:
bactericidal or bacteriostatic - ANSWERS--bactericidal
Which antibiotics are preferred for patients with an overwhelming
infection: bactericidal or bacteriostatic - ANSWERS--bactericidal
Broad spectrum antibiotics - ANSWERS--affect a broad range of gram-
positive or gram-negative bacteria
Narrow spectrum antibiotics - ANSWERS--Effective against specific
bacteria
Which is used for empiric therapy: narrow or broad - ANSWERS--broad
spectrum
Risks of Broad Spectrum - ANSWERS--disruption of normal floral
increases risk of development of antibiotic resistance
Which antibiotics increase the risk of antibiotic resistance: narrow or
broad spectrum and why - ANSWERS--Broad spectrum because they kill
more competing organisms than narrow spectrum drugs
Is narrow or broad spectrum antibiotics preferred - ANSWERS--narrow
is preferred when possible.
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broad spectrum only used when pathogen is unknown or when
multiple types of bacteria is suspected
Bactericidal drugs - ANSWERS--Aminoglycosides
Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)
Bacteriostatic drugs - ANSWERS--clindamycin
macrolides
sulfonamides
tetracyclines
When is empiric therapy used? - ANSWERS--when treatment is started
without cultures or when culture results are not back yet
Who needs empiric therapy - ANSWERS--critically ill pts after first set of
cxs
hospitalized pts until css are available
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ambulatory pts based on clinical presentation
Penicillins MOA - ANSWERS--inhibit cell wall synthesis; bactericidal
Penicillins primarily excreted how - ANSWERS--in urine
What needs to be monitored when giving penicillins - ANSWERS--renal
function
What happens if renal insufficiency occurs while giving penicillins -
ANSWERS--prolonged half-life leading to toxicity
Penicillin distribution - ANSWERS---Well distributed to most body
tissues
-Penetration to CSF and eye tissues poor in absence of inflammation
Narrow-spectrum penicillinase sensitive drugs - ANSWERS--penicillin G
penicillin V
Narrow-spectrum penicillinase sensitive susceptible pathogens -
ANSWERS--streptococci, Neisseria, anaerobes
Narrow-spectrum penicillinase resistant drugs - ANSWERS--naficillin