Questions and Guide Answers
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1. What drugs should be avoided with Kava Kava?
Answer: Alprazolam, CNS depressants (e.g., pheno- barbital, zolpidem)
2. What are the 3 functions of a Cultural Formulation Interview?
Answer: Clarify meaning of illness, Empower the patient, Validate symptoms within the cultural context
3. What does a cultural formulation interview do?
Answer: Cultural assessment
4. What is the normal range for TSH?
Answer: 0.5 - 5.0 mu/L
5. What are lab values in Hyperthyroidism?
Answer: Decreased TSH, Increased T4 and T3
6. What are lab values in Hypothyroidism?
Answer: Increased TSH, Decreased T4 and T3
7. What are 5 primary symptoms of Hyperthyroidism?
,Answer: Heat intolerance, Agitation, Anxiety, Irritability, Tachycardia, Mood swings, Weight loss
8. What are 4 primary symptoms of Hypothyroidism?
Answer: Cold intolerance, Lethargy, Weight gain, Decreased libido
9. Hypothyroidism mimics symptoms of what psychiatric disorder?
Answer: Depression
10. Hyperthyroidism mimics symptoms of what psychiatric disorder?
Answer: Mania
11. What teratogenic effect does Valproic acid produce?
Answer: Spina bifida (neural tube defect)
12. What is the primary organ where Valproic acid is toxic?
Answer: Liver (hepatotoxicity)
13. What are 4 signs of hepatotoxicity?
Answer: Abdominal pain in the RUQ, Reddish-brown urine, Yellowing of the skin and sclera, Fatigue
14. What is the therapeutic range for Valproic acid?
Answer: 50-125 mcg/ml
15. What is a toxic level of Valproic acid?
Answer: >150 mcg/ml
16. What are 4 signs of Valproic acid toxicity?
Answer: Disorientation, Lethargy, Respiratory depression, Nausea/vomiting
,17. With suspected toxicity from Valproic acid, what labs should be drawn?
Answer: D/C drug, Check drug level, Obtain LFTs, Obtain ammonia level
18. What is the major side effect of Kava Kava?
Answer: Liver damage
19. What herbal supplement is used for anxiety, stress, and insomnia?
Answer: Kava Kava
20. What are 5 symptoms of Stephen's Johnson Syndrome?
Answer: Fever, Body aches, Severe red rash, Peeling skin, Facial and tongue swelling
21. Which mood stabilizer causes the least weight gain?
Answer: Lamotrigine (Lamictal)
22. Which 3 SGAs cause the least weight gain?
Answer: Lurasidone (Latuda), Aripiprazole (Abilify), Ziprasidone (Geodon)
23. Which SGA is the least sedating?
Answer: Aripiprazole (Abilify)
, 24. What are 3 hallmark symptoms of delirium?
Answer: Acute disturbance of LOC, Impaired cognition, Inattention
25. How are agitation and psychotic symptoms treated in delirium?
Answer: Low dose Haldol
26. What 4 drugs can cause mania?
Answer: Steroids, Disulfiram (Antabuse), Isoniazid (INH), Antidepressants (in BPD)
27. What 6 drugs can induce depression?
Answer: Steroids, Beta blockers, Interferon, Isotretinoin (Accu- tane), Retroviral drugs, Antineoplastic
drugs, Benzodiazepines, Progesterone
28. Steroids can induce what 3 psychiatric states?
Answer: Mania, Depression, Psychosis
29. What medication used to treat acne can cause birth defects?
Answer: Isotretinoin (Accutane)
30. What is agranulocytosis?
Answer: <500 ANC
31. What is neutropenia?
Answer: <2000 PMNs (neutrophils)
32. What ANC level should clozapine be stopped?