TEST 2026 | MRI PHYSICS, IMAGE FORMATION
& SAFETY (300+ VERIFIED Q&A)
1. Which nucleus is most commonly used for clinical MRI and why?
A. Hydrogen-2 (deuterium)
B. Carbon-13
C. Hydrogen-1 (proton)
D. Phosphorus-31
E. Sodium-23
CORRECT ANSWER: C
RATIONALE:
Hydrogen-1 (the proton) is the most abundant MRI-sensitive nucleus in the human body
because of the high concentration of water and fat, both of which contain hydrogen.
Protons have a relatively large gyromagnetic ratio, producing a strong magnetic
moment and thus strong signal for a given field strength, improving sensitivity. They also
have favorable relaxation properties (T1 and T2) that allow tissue contrast to be
manipulated with pulse sequence parameters. Other nuclei like carbon-13, phosphorus-
31, or sodium-23 can be imaged but are far less abundant and have lower sensitivity,
requiring specialized coils and often hyperpolarization or long acquisition times.
Deuterium has a much lower gyromagnetic ratio and is rare in tissues compared to
hydrogen-1. Therefore, clinical MRI uses protons for optimal signal-to-noise ratio (SNR)
and practical imaging times.
2. What is the Larmor frequency equation for a nucleus in a magnetic field?
A. f = m × B0
B. f = γ / B0
C. f = γ × B0
D. f = B0 / γ
E. f = 2π × γ × B0
CORRECT ANSWER: C
RATIONALE:
The Larmor frequency f (in Hz) describes the precessional frequency of nuclear
magnetic moments in an external static magnetic field B0 and is given by f = γ × B0,
where γ is the gyromagnetic ratio (in Hz/T). This linear relationship means frequency
increases proportionally with field strength. Option E resembles the angular frequency ω
= 2πf = γ × B0 (if γ is in rad/s/T), but the standard Larmor equation for frequency uses f
= γ × B0 with γ in Hz/T. Options A, B, and D are incorrect algebraically; only C matches
the correct physical relation.
, 3. Which property describes the time constant for longitudinal magnetization
recovery after an RF pulse?
A. T2*
B. T2
C. TR
D. TE
E. T1
CORRECT ANSWER: E
RATIONALE:
T1 is the longitudinal relaxation time that characterizes the exponential recovery of the
net magnetization vector along the direction of the static magnetic field (z-axis) toward
thermal equilibrium after being tipped by an RF pulse. T1 reflects energy exchange
(spin-lattice relaxation) between the spin system and its environment, with tissues
having different T1 values that can be exploited for contrast. T2 and T2* relate to
transverse relaxation (loss of phase coherence). TR is a sequence timing parameter
(repetition time), and TE is echo time. Thus the time constant describing longitudinal
recovery is T1.
4. Which factor contributes to T2 shortening beyond intrinsic T2 processes?*
A. Spin-lattice interactions only
B. Increased molecular tumbling
C. Magnetic field inhomogeneities and susceptibility differences
D. Longer TR
E. Higher proton density
CORRECT ANSWER: C
RATIONALE:
T2* accounts for observed decay of transverse magnetization and includes both intrinsic
spin-spin dephasing (T2) and additional dephasing from static magnetic field
inhomogeneities and susceptibility variations. These inhomogeneities cause spins to
precess at slightly different frequencies, leading to faster apparent decay than T2 alone.
Spin-lattice interactions relate to T1, not T2*. TR and proton density do not directly
shorten T2*; they affect signal magnitude and contrast. Therefore, field inhomogeneities
and susceptibility differences are principal contributors to T2* shortening.
5. Which pulse sequence is primarily used to acquire T2-weighted images
with minimal T1 weighting?
A. Gradient-echo with short TE
B. Spin-echo with long TE and long TR
C. Inversion recovery with short TI
, D. Echo-planar imaging with short TR
E. Gradient-echo with flip angle 90°
CORRECT ANSWER: B
RATIONALE:
A conventional spin-echo sequence with a long echo time (TE) and long repetition time
(TR) minimizes T1 weighting and accentuates T2 weighting, because a long TR reduces
differential longitudinal recovery effects (T1 contrast), and a long TE allows tissues with
shorter T2 to lose transverse magnetization, highlighting differences due to T2.
Gradient-echo sequences are more susceptible to T2* effects and can have residual T1
weighting depending on TR and flip angle. Inversion recovery with short TI emphasizes
T1 suppression for specific tissues. EPI and gradient echo with 90° flip are not standard
for pure T2-weighting. Thus spin-echo long TE/TR is the correct choice.
6. What is k-space?
A. Physical location of the RF coil
B. The hardware controlling gradients
C. A spatial frequency domain where MRI raw data are stored before image
reconstruction
D. The patient table coordinate system
E. A measure of SAR distribution
CORRECT ANSWER: C
RATIONALE:
K-space is the two-dimensional (or three-dimensional) spatial frequency domain in
which MRI signal data are collected during acquisition. Each point in k-space
corresponds to a specific spatial frequency component of the final image; the central k-
space contains low spatial frequencies (contrast/overall signal), and the periphery
contains high frequencies (fine detail/resolution). Image reconstruction commonly uses
the inverse Fourier transform of k-space data to produce the spatial-domain image. K-
space is a conceptual and mathematical space, not a physical coil location or hardware
component.
7. Which gradient axis controls frequency encoding in a standard 2D imaging
sequence?
A. Slice-selection gradient
B. Phase-encoding gradient
C. Frequency-encoding (readout) gradient
D. RF gradient
E. Shim gradient
, CORRECT ANSWER: C
RATIONALE:
In 2D imaging, the frequency-encoding gradient (also called the readout gradient) is
applied during signal acquisition and encodes spatial information along one axis by
creating a linear variation in Larmor frequency across the object; this allows frequency
discrimination during readout. The phase-encoding gradient imparts position-dependent
phase shifts across the orthogonal in-plane axis prior to acquisition. Slice-selection
gradient selects the imaging slice during the RF pulse. Shim gradients improve field
homogeneity. Therefore the frequency-encoding gradient controls frequency encoding.
8. What determines in-plane spatial resolution in MRI?
A. TR and TE
B. Field strength only
C. Matrix size and field of view (FOV)
D. Bandwidth only
E. Proton density
CORRECT ANSWER: C
RATIONALE:
In-plane resolution is determined by the pixel dimensions, which are the field of view
(FOV) divided by the acquisition matrix size in each direction (frequency and phase):
pixel size = FOV / matrix size. Increasing the matrix size (more phase or frequency
encoding steps) or decreasing FOV improves resolution, though at the cost of increased
scan time or potential aliasing. TR, TE, field strength, bandwidth, and proton density
influence contrast, SNR, and other image qualities, but the direct mathematical
determinants of spatial resolution are FOV and matrix.
9. Which action reduces chemical shift artifact in the frequency-encoding
direction?
A. Increase TR
B. Increase receiver bandwidth
C. Use longer TE
D. Decrease matrix size
E. Use inversion recovery
CORRECT ANSWER: B
RATIONALE:
Chemical shift artifact arises due to the difference in resonance frequency between fat
and water; when frequency-encoding is used, this causes misregistration (shift) along
that axis. Increasing receiver bandwidth reduces the frequency-to-position mapping