Fundamental Molecular Biology
Primary Reference: Fundamental Molecular Biology by
Lizabeth A. Allison.
Curriculum Alignment: Based on Oxford University
Reading List for Medical & Biological Sciences.
Key Terms: Nucleotide& DNA Double Helix&Base
Pairing &Phosphodiester Bond&Antiparallel Strands
High-Quality Summary and Key Points Focused On The
Exam-.
Chapter : two
1
, DNA Structure – Clean Study Summary
1. Core Idea
DNA is the genetic material responsible for storing and
transmitting genetic information.
The key principle is: structure determines function.
2. Nucleotide Structure
DNA is composed of units called nucleotides, each
consisting of:
1) A deoxyribose sugar
2) A phosphate group
3) A nitrogenous base
Types of Bases:
Purines: A, G
Pyrimidines: C, T
3. DNA Backbone & Direction
Nucleotides are linked by phosphodiester bonds
Each strand has a direction: 5′ → 3′
This direction is essential for:
DNA replication
Transcription
2