NR565 / NR 565 Advanced Pharmacology Fundamentals
Final Exam – Chamberlain
Actual Questions with Verified Answers
1. In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
Answer: C. Alcoholics
2. What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
, Answer: A. eGFR <30
3. What medication is contraindicated to treat diabetes if a patient already has a
cardiac ejection fraction rate of 40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor
Answer: B. Thiazolidinediones
4. Sabrina is a 35-year-old female who presents with complaints of fatigue,
anxiety, and palpitations. She has a long history of obesity and reports that
she is happy that she has lost 23 pounds in the last 2 months. She also reports
that she has trouble sleeping and her husband complains that she is keeping
the house too cold. Physical exam reveals slight tachycardia at 104 bpm and
a slightly enlarged thyroid. Thyroid testing reveals hyperthyroidism or Grave's
disease.
Which of the following agents is the first-line treatment for hyperthyroidism or
Grave's disease?
A. Methimazole
,B. Metoprolol
C. Allopurinol
D. Levothyroxine
Answer: A. Methimazole
5. Which of the following medications would be considered the first line of
treatment for a newly diagnosed Diabetic patient with adequate renal and
hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
Answer: C: Oral Metformin
6. Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
, Answer: B. Insulin
7. Which symptoms are most expected of a patient diagnosed with hypothy-
roidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
Answer: D. dry skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital infections or an active
diagnosis, should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.
Answer: C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic for
a follow-up appointment. The healthcare provider has prescribed metformin
Final Exam – Chamberlain
Actual Questions with Verified Answers
1. In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
Answer: C. Alcoholics
2. What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
, Answer: A. eGFR <30
3. What medication is contraindicated to treat diabetes if a patient already has a
cardiac ejection fraction rate of 40%?
A. Second Generation sulfonyureas
B. Thiazolidinediones
C. Dopamine Agonist
D. Glucosidase Inhibitor
Answer: B. Thiazolidinediones
4. Sabrina is a 35-year-old female who presents with complaints of fatigue,
anxiety, and palpitations. She has a long history of obesity and reports that
she is happy that she has lost 23 pounds in the last 2 months. She also reports
that she has trouble sleeping and her husband complains that she is keeping
the house too cold. Physical exam reveals slight tachycardia at 104 bpm and
a slightly enlarged thyroid. Thyroid testing reveals hyperthyroidism or Grave's
disease.
Which of the following agents is the first-line treatment for hyperthyroidism or
Grave's disease?
A. Methimazole
,B. Metoprolol
C. Allopurinol
D. Levothyroxine
Answer: A. Methimazole
5. Which of the following medications would be considered the first line of
treatment for a newly diagnosed Diabetic patient with adequate renal and
hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
Answer: C: Oral Metformin
6. Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
, Answer: B. Insulin
7. Which symptoms are most expected of a patient diagnosed with hypothy-
roidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
Answer: D. dry skin, brittle hair, fatigue, myxedema
8. Patients with an increased risk for UTIs and genital infections or an active
diagnosis, should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.
Answer: C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic for
a follow-up appointment. The healthcare provider has prescribed metformin
