APHON Principles of Chemo and Biotherapy Exam| Complete
Exam Questions and CORRECT Answers| (2026 update)
Assured success
Biotherapy
Targeted anticancer agents also known as biological response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what class
Biotherapy
Monoclonal antibodies (MoAbs) are what class
Biotherapy
Define pharmacokinetics
Study of drug absorption, metabolism, and excretion
Define pharmacodynamics
The concentration of the drug in the body and how it produces a response
Define adjuvant chemotherapy
The use of chemo after another type of therapy, such as surgery, to treat residual
disease or undetectable metastasis.
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Define neoadjuvant chemotherapy
When chemo is used preoperatively to decrease tumor burden in order to make
it easier to remove the tumor surgically.
Define sanctuary sites
Sites within the body where tumor cells sequester and are not easily reached by
chemo such as the CNS
What normal cells are most often effected by chemotherapy
Hematopoietic, mucosal (mouth & GI), hair follicles
Why use chemotherapy
To prevent cancer cells from dividing, metastasizing, and ultimately causing the
death of the patient
Cure
To permanently eradicate the cancer
Control
To extend the length & QOL when cure is not feasible or realistic
Palliation
Minimize pain and suffering during end of life
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