NEWEST COMPLETE
QUESTIONS AND CORRECT ANSWERS
LATEST EXAM
What is reserpine? - CORRECT ✔✔- Causes extreme
ANSWER sedation
than can be reversed by DOPA
- Blocks VMAT
Catecholamine release and locomotor activityCORRECT ✔✔-
- ANSWER
Released by exocytosis
- Increase in locomotor activity
- Inhibited by auto receptors
How are catecholamines inactivated? Reuptake transporters and enzymes.
-
CORRECT ✔✔- Reuptake by DA transporter or NE tranporter
ANSWER
- Metabolic breakdown by COMT and MAO
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,What is the nigrostriatal pathway? Where are the cell bodies located? -
CORRECT ✔✔- Plays and important role in the control of
ANSWER
movement
- Originates in substantia nigra where axons ascend to the
caudateputamen (striatum)
What is Parkinson's disease? -CORRECT ✔✔- Damage of
ANSWER
nigrostriatal pathway (substantia nigra)
- Neurodegenative disease
- When cells that normally produce dopamine die, the sypmtoms of
Parkinson's appear
- MIST
Dopamine Antagonist: Haloperidol (D2 antagonist)CORRECT
-
ANSWER✔✔At high doses results in catalepsy (catetonic
state)
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, Where are Noradrenergic (NE) cell bodies located?CORRECT
-
ANSWER✔✔Locus
coeruleus
Locus coeruleus is involved in what type of behavior?CORRECT
-
ANSWER✔✔Vigilance
What is MPTP? - CORRECT ✔✔- A
ANSWER neurotoxin
- Contaminant in sythetic heroin that caused symptoms of Parkinson's
disease in drug addicts
- Caused a loss of neurons in substantia nigra
Mesolimbic system - CORRECT ✔✔- Originates in the ventral
ANSWER
tegmental area (VTA) and axons travel to the nucleus accumbens and
olfactory nuclus
- Involved in drug abuse
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