NSG 522 PSYCHOPHARMACOLOGY FINAL
EXAM
QUESTIONS AND CORRECT ANSWERS
Chronic methamphetamine use has been associated with all of the
following
Except
A) psychosis and flashbacks
B) Enhanced cognition
C) Increased risk of stroke and myocardial infarction
D) Premature aging - CORRECT ✔✔Premature
ANSWER aging
Most behavioral and physiological actions related to cocaine can be
explained by - CORRECT ✔✔The ability to block reuptake
ANSWER of
serotonin,
the ability to block reuptake of dopamine, the
ability to block reuptake of norephinephrine
Page 1 of 42
,2 | Page
Which is the fastest way to get nicotine to the brain -CORRECT
ANSWER✔✔Smoking
Which of the following about the metabolism of nicotine is accurate? -
CORRECT ✔✔It yields the principal metabolite
ANSWER cotinine
the liver enzyme CYP2A6 is involved
The process of releasing neurotransmitter molecules from the vesicles is
known as _____ and occurs as a result of an influx of _____CORRECT
-
ANSWER✔✔Exocytosis;
Ca2+
Depot binding is said to occur when drugs -CORRECT ✔✔Bind
ANSWER to
inactive sites
During the ____ period, no additional action potentials can be created -
CORRECT ✔✔Absolute
ANSWER refractory
,3 | Page
Neural transmission is generally ____ within a single neuron and ____
between neurons. - CORRECT ✔✔Electrical;
ANSWER chemical
The most common type of synapse in the brain is the ______ synapse -
CORRECT ✔✔Axodendritic
ANSWER
Neurons rely on ____ for protection, metabolic support and insulation -
CORRECT ✔✔Glial
ANSWER cells
Which of the following factors does NOT affect the pharmokinetics of a
drug?
A) Route of Administration
B) Lipid solubility
C) Depot binding
D) Drug action - CORRECT ✔✔Drug
ANSWER action
The sac-like structures in the presynaptic terminal are called ______ and
are filled with _______ - CORRECT ✔✔Synaptic
ANSWER vesicles;
Page 3 of 42
, 4 | Page
neurotransmitter molecules
Cocaine acts in the nervous system by blocking ______ and __________ -
CORRECT ✔✔Monoamine transporters; voltage-gated
ANSWER sodium
channels
Which of the following about cocaine administration and absorption is
true?
A) Rapid absorption occurs with intravenous and smoked forms of
cocaine B) Cocaethylene is a metabolite of cocaine and alcohol that exerts
an effect similar to cocaine, but that lasts for a longer time.
C) Smoking crack cocaine is addictive because the brain receives a large
surge of drug, even though its effects don't last very long
D) All of the above are true -CORRECT ✔✔D) All of the above are
ANSWER
true
Chronic, high dose use of psychostimulants can lead to all of the following
effects except
A) increased sexual interest