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Galen NUR 265 | Exam 2 Set 1 Practice Test | 150 Questions & Rationales | Med-Surg 2026

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Pass the Galen NUR 265 Med-Surg Exam 2 with this comprehensive 150-question practice test for 2026. This digital download contains 150 unique questions with detailed rationales, covering the essential topics for NUR 265 Exam 2, Set 1. Designed specifically for Galen College of Nursing students, this resource reinforces clinical judgment and critical thinking. What’s included in this PDF: 150 Practice Questions with correct answers and "why" rationales. Exam Blueprint Topics Covered: Perioperative & Postoperative Care: Hemorrhage recognition, airway priority, malignant hyperthermia (muscle rigidity, hyperthermia, dantrolene), Jackson-Pratt drain output (100 mL/hr = hemorrhage), post-op PE (oxygen, notify provider), pneumonia risk factors (age, smoking, abdominal surgery), urinary retention (bladder scan first), wound infection (purulent drainage), early mobilization, neostigmine for neuromuscular blockade reversal, chest tube function, epidural anesthesia complications (respiratory rate 8), DVT prophylaxis (SCDs, early ambulation, enoxaparin), post-thyroidectomy hypocalcemia (tetany, calcium gluconate). Wound Healing & Pressure Injuries: Pressure injury staging (Stage 4 = visible bone), corticosteroids delay healing, dehiscence management (saline-moistened sterile dressing), albumin for healing assessment, black eschar on heel (keep dry, offload, do not debride), Vitamin C and zinc for healing, serosanguineous drainage (pink, watery), purulent drainage indicates infection, repositioning every 2 hours, slough requires debridement, highest risk (paralyzed + incontinent), primary intention healing, loose packing for undermining, red granulation tissue indicates healing. Advanced Fluid & Electrolytes: SIADH (dilutional hyponatremia, fluid restriction, 3% saline for severe symptoms), increased ICP (3% hypertonic saline), hypocalcemia (Chvostek's sign), pancreatitis hypocalcemia (saponification), hypernatremia (hypotonic IV fluids), hypokalemia (U waves, hold furosemide if K+ 3.0), dehydration (BUN/Creatinine ratio 20:1), hyperkalemia with wide QRS (calcium gluconate first), SIADH treatment success (serum sodium rises), hypomagnesemia (tetany, tremors), hypermagnesemia risk (CKD + magnesium supplements), fluid overload (HOB up + diuretics), hypophosphatemia (muscle weakness, respiratory failure), DKA (insulin → monitor potassium closely), hypercalcemia (IV fluids first), hyperkalemia ECG (peaked T waves), hyperchloremia (metabolic acidosis), bulimia hypokalemia (cardiac arrhythmias priority). Immunology & Transfusion: Transfusion reaction (stop transfusion first), anaphylactic reaction risk (IgA deficiency), CKD anemia (epoetin alfa), direct Coombs test (autoimmune hemolytic anemia), hemophilia A (Factor VIII replacement), ITP with new headache (intracranial hemorrhage risk), live vaccines contraindicated with high-dose steroids, CD4 200 = AIDS diagnosis, febrile neutropenia (notify provider immediately), TACO (dyspnea, crackles from fluid overload), lupus (avoid sun exposure), methotrexate (folic acid for side effects), scleroderma Raynaud's (keep hands warm), myasthenia gravis worsening after pyridostigmine (cholinergic crisis), Guillain-Barré with dysphagia (prepare for intubation), SLE proteinuria (renal involvement), ankylosing spondylitis (deep breathing exercises), acute gout flare (colchicine or NSAIDs), Sjögren's syndrome (artificial tears, saliva substitutes), IVIG (monitor for hypotension, headache, aseptic meningitis). Sepsis & Infectious Diseases: Septic shock (IV fluids first, then vasopressors, MAP target 65 mmHg), DIC in sepsis (elevated D-dimer, low fibrinogen), sepsis with organ dysfunction (altered mental status, hypotension, oliguria), broad-spectrum IV antibiotics within 1 hour, C. diff (contact precautions + bleach), MRSA vancomycin (monitor trough level), bacterial meningitis (droplet precautions), HIV with CD4 50 (PJP pneumonia), TB contagiousness (three negative sputum smears), shingles (localized = contact; disseminated/immunocompromised = airborne + contact), catheter-related bloodstream infection (positive line and peripheral cultures with same organism), influenza worsening day 5 (secondary bacterial pneumonia), endocarditis (Staph aureus or Strep viridans), osteomyelitis (fever + elevated ESR/CRP), urosepsis (IV fluids and antibiotics), wound culture (obtain before antibiotics), varicella in immunocompromised (airborne + contact precautions), malaria fever (parasite replication cycle), Lyme disease (doxycycline). Oncology & Palliative Care: Thrombocytopenia (avoid electric razors), neutropenia with visitor with cold (restrict visitor), pain management goal (pain 3/10 after morphine), SVC syndrome (facial/upper extremity swelling), tumor lysis syndrome (rasburicase or allopurinol), tamoxifen (report leg pain/swelling for DVT risk), healthy stoma (red, moist, document as normal), cisplatin (report tinnitus → ototoxicity), refractory CINV (aprepitant), death rattle (reposition, scopolamine, educate family), DNR/DNI (honor advance directives, treat infection with antibiotics/oxygen), leukostasis (hydration + hydroxyurea), central line fever during infusion (stop, assess for line infection), hypercalcemia of malignancy (IV fluids first), doxorubicin cardiotoxicity (decreased ejection fraction), radiation burn care (mild soap and water, no alcohol), multiple myeloma (lytic bone lesions → pathologic fracture), clinical trial (ensure informed consent understood), Karnofsky score 30 (severely disabled), vincristine (stool softeners for constipation), brain tumor seizure (protect airway, benzodiazepine), leuprolide hot flashes (expected side effect), DNR (comfort care only in arrest), pancreatic cancer jaundice (biliary obstruction), chemotherapy-induced anemia (transfusion or ESA). Pain Management & Palliative Care: Opioid-induced respiratory depression (naloxone first), fentanyl patch (do not cut or apply heat), neuropathic pain (gabapentin/pregabalin), ineffective PCA (assess pump function, notify provider), pre-medicate for procedural pain, terminal restlessness (lorazepam), opioid tolerance vs. addiction (tolerance and dependence expected, not addiction), liver failure pain (acetaminophen reduced dose, avoid NSAIDs), epidural analgesia (assess motor block, notify provider if excessive), dyspnea at EOL (fan, open window, upright positioning), MAID (nurse can refuse to participate but provide nonjudgmental care), DNI (non-invasive ventilation allowed), opioid myoclonus (neurotoxicity, may need rotation), noisy secretions not distressing patient (reposition, educate family, avoid aggressive suctioning), anorexia at EOL (normal, do not force feed). Prioritization & Delegation: Febrile neutropenia with hypotension (see first), UAP delegation (empty Foley catheter, record output), LPN assignment (stable pneumonia on oral antibiotics), new dysphagia after stroke (place NPO, assess), most experienced RN for IVIG/Guillain-Barré, PCA with RR 6 (stop PCA, give naloxone), new graduate RN (stable post-op cholecystectomy), sepsis vital signs delegation (report SBP 90), DNR with respiratory distress (oxygen + comfort care), new confusion + fever (assess first), RN to LPN delegation (insert Foley catheter), UAP reports low SpO2 (assess patient immediately), new RN hanging potassium IV push (immediate intervention - lethal), wet central line dressing (RN assess and change sterilely), fever with rigors (assess first). Perfect for: Exam 2, Set 1 preparation for NUR 265. Remediation and content review. Practicing clinical judgment (NGN-style scenarios). This is an original educational practice exam created to supplement course materials.

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Institution
Galen NUR 265
Course
Galen NUR 265

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Galen NUR 265 – Med-Surg Exam 2, Set 1
(Practice Exam) 150 Questions with Answers
& Rationales



Section 1: Perioperative & Postoperative Care (Q1–20)
1. A patient is 2 hours post-op from abdominal surgery. Which
finding requires immediate notification of the surgeon?
A. Pain rated 5/10
B. Heart rate 110 bpm, BP 88/50
C. Urine output 40 mL/hr
D. Temperature 99.8°F (37.7°C)
Answer: B – Heart rate 110 bpm, BP 88/50
Rationale: Tachycardia with hypotension suggests hypovolemia or
hemorrhage.
2. A patient received general anesthesia. The nurse’s priority in the
immediate post-op period is:
A. Pain management
B. Airway patency
C. Wound assessment
D. Fluid replacement
Answer: B – Airway patency
Rationale: Airway is always first; anesthesia can cause airway
obstruction.

,3. Which assessment finding indicates malignant hyperthermia?
A. Hypothermia and bradycardia
B. Muscle rigidity and hyperthermia
C. Hypotension and polyuria
D. Respiratory depression and miosis
Answer: B – Muscle rigidity and hyperthermia
Rationale: Malignant hyperthermia is a life-threatening reaction to
volatile anesthetics/succinylcholine.
4. A patient post-op has a Jackson-Pratt drain with 150 mL of bright
red blood in 1 hour. What should the nurse do first?
A. Document as normal
B. Empty the drain
C. Notify the provider
D. Apply pressure to the site
Answer: C – Notify the provider
*Rationale: >100 mL/hr suggests active bleeding.*
5. Which instruction is correct for a patient after outpatient
surgery with general anesthesia?
A. “You may drive yourself home.”
B. “Do not drink alcohol for 24 hours.”
C. “Return to work tomorrow.”
D. “You can eat a full meal immediately.”
Answer: B – “Do not drink alcohol for 24 hours.”
Rationale: Alcohol interacts with anesthesia and sedatives; impairs
recovery.
6. A patient post-op reports sudden chest pain and dyspnea. The
nurse suspects pulmonary embolism. The priority action is:

,A. Give aspirin
B. Apply oxygen and notify provider
C. Ambulate the patient
D. Administer morphine
Answer: B – Apply oxygen and notify provider
Rationale: Oxygenation and rapid treatment are critical for PE.
7. Which patient is at highest risk for postoperative pneumonia?
A. 30-year-old having knee arthroscopy
B. 65-year-old smoker with abdominal surgery
C. 20-year-old with tonsillectomy
D. 45-year-old with cataract surgery
Answer: B – 65-year-old smoker with abdominal surgery
Rationale: Older age, smoking, and abdominal incision (splinting)
increase pneumonia risk.
8. A patient post-op has not voided for 8 hours and reports
suprapubic discomfort. What should the nurse do first?
A. Insert a Foley catheter
B. Bladder scan
C. Increase IV fluids
D. Encourage ambulation
Answer: B – Bladder scan
Rationale: Bladder scan determines urinary retention
non-invasively.
9. Which finding in the first 24 hours post-op is most concerning
for infection?
A. WBC 12,000/µL
B. Temperature 100.2°F (37.9°C)

, C. Purulent drainage from incision
D. Pain at incision site
Answer: C – Purulent drainage from incision
Rationale: Purulent drainage indicates infection; fever and mild
leukocytosis are expected post-op.
10. A patient is 6 hours post-op and has not ambulated. The nurse’s
best action is:
A. Wait until tomorrow
B. Assist the patient to sit at the bedside
C. Notify physical therapy
D. Apply sequential compression devices only
Answer: B – Assist the patient to sit at the bedside
Rationale: Early mobilization prevents DVT, atelectasis, and ileus.
11. Which medication is given to reverse the effects of
neuromuscular blockers?
A. Naloxone
B. Neostigmine
C. Flumazenil
D. Protamine
Answer: B – Neostigmine
Rationale: Neostigmine (with glycopyrrolate) reverses
non-depolarizing neuromuscular blockers.
12. A patient post-op has a nasogastric tube to low intermittent
suction. Which finding indicates the tube is functioning correctly?
A. Nausea and vomiting
B. Abdominal distention
C. Output of 800 mL green fluid in 8 hours

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