NAPLEX HYPERTENSION MANAGEMENT
EXAM 2026 WITH 100% ACCURATE
ANSWERS
1. What is the primary mechanism of action of angiotensin receptor
blockers (ARBs)?
They block the action of angiotensin II.
They inhibit the production of renin.
They increase sodium reabsorption in the kidneys.
They dilate blood vessels by increasing nitric oxide.
2. What are the specific conditions under which beta blockers are not
recommended as a first-line treatment for hypertension?
In patients with asthma or chronic obstructive pulmonary
disease (COPD).
In patients with diabetes mellitus.
In patients over the age of 65.
In patients with a history of heart failure.
3. What class of medication is recommended for hypertension treatment in
black patients?
ACE inhibitors
Calcium channel blockers or thiazide diuretics
Beta-blockers
Angiotensin II receptor blockers
4. Olmesartan is the active ingredient of which of the following brand
name medications?
, Coumadin
Verelan
Inderal
Cozaar
Benicar
5. Describe how angiotensin receptor blockers (ARBs) contribute to the
management of hypertension.
ARBs lower blood pressure by blocking angiotensin II, which
causes blood vessels to relax and reduces fluid retention.
ARBs have no effect on blood pressure but are used to treat
heart failure.
ARBs increase blood pressure by promoting vasoconstriction
and fluid retention.
ARBs primarily work by increasing heart rate and cardiac output.
6. What are two common side effects associated with non-DHP calcium
channel blockers?
Dry mouth and rash
Nausea and vomiting
Bradycardia and constipation
Headache and dizziness
7. It is not just the number on the scale that we should focus on when
trying to obtain a healthy weight. Our waist circumference is also an
important measurement to keep under control. Ideally, females should
aim for a waist circumference of less than ___ inches, and males should
aim for a waist circumference of less than ___ inches.
, 35; 40
30; 35
40; 45
25; 30
8. What is the primary mechanism of action of ACE inhibitors?
They block calcium channels in the heart.
They increase the excretion of sodium and water.
They inhibit the conversion of angiotensin I to angiotensin II.
They stimulate the release of aldosterone.
9. Describe the significance of beta-1 selective beta blockers in the
treatment of hypertension.
Beta-1 selective beta blockers are used only for heart failure and
have no effect on hypertension.
Beta-1 selective beta blockers increase heart rate and blood
volume, which can lead to higher blood pressure.
Beta-1 selective beta blockers work by dilating blood vessels,
which lowers blood pressure.
Beta-1 selective beta blockers primarily reduce heart rate and
myocardial contractility, making them effective in lowering
blood pressure.
10. What are the two non-DHP calcium channel blockers (CCBs)?
Amlodipine and Nifedipine
Lisinopril and Enalapril
Diltiazem and Verapamil
, Hydrochlorothiazide and Furosemide
11. In a patient with hypertension who is also at risk of hypokalemia, which
medication class would be most appropriate to consider for their
treatment?
Loop diuretics
Thiazide diuretics
Calcium channel blockers
Potassium-sparing diuretics
12. Which of the following correctly describes the action of Calcium
Channel Blockers in the treatment of hypertension?
NDHP CCBs act primarily on the kidney to lower blood pressure
DHP CCBs act primarily on the kidney to decrease BP
DHP CCBs act primarily in the vasculature to lower blood
pressure
Dihydropyridine calcium channel blockers (DHP CCBs) act
primarily on the heart to lower blood pressure
Non-dihydropyridine calcium channel blockers (NDHP CCBs)
act primarily in the vasculature to lower blood pressure
13. Describe how thiazide diuretics contribute to lowering blood pressure.
Thiazide diuretics directly relax blood vessel walls.
Thiazide diuretics lower blood pressure by reducing blood
volume and decreasing peripheral vascular resistance.
Thiazide diuretics increase heart rate, which lowers blood
pressure.
Thiazide diuretics increase sodium retention, which lowers blood
EXAM 2026 WITH 100% ACCURATE
ANSWERS
1. What is the primary mechanism of action of angiotensin receptor
blockers (ARBs)?
They block the action of angiotensin II.
They inhibit the production of renin.
They increase sodium reabsorption in the kidneys.
They dilate blood vessels by increasing nitric oxide.
2. What are the specific conditions under which beta blockers are not
recommended as a first-line treatment for hypertension?
In patients with asthma or chronic obstructive pulmonary
disease (COPD).
In patients with diabetes mellitus.
In patients over the age of 65.
In patients with a history of heart failure.
3. What class of medication is recommended for hypertension treatment in
black patients?
ACE inhibitors
Calcium channel blockers or thiazide diuretics
Beta-blockers
Angiotensin II receptor blockers
4. Olmesartan is the active ingredient of which of the following brand
name medications?
, Coumadin
Verelan
Inderal
Cozaar
Benicar
5. Describe how angiotensin receptor blockers (ARBs) contribute to the
management of hypertension.
ARBs lower blood pressure by blocking angiotensin II, which
causes blood vessels to relax and reduces fluid retention.
ARBs have no effect on blood pressure but are used to treat
heart failure.
ARBs increase blood pressure by promoting vasoconstriction
and fluid retention.
ARBs primarily work by increasing heart rate and cardiac output.
6. What are two common side effects associated with non-DHP calcium
channel blockers?
Dry mouth and rash
Nausea and vomiting
Bradycardia and constipation
Headache and dizziness
7. It is not just the number on the scale that we should focus on when
trying to obtain a healthy weight. Our waist circumference is also an
important measurement to keep under control. Ideally, females should
aim for a waist circumference of less than ___ inches, and males should
aim for a waist circumference of less than ___ inches.
, 35; 40
30; 35
40; 45
25; 30
8. What is the primary mechanism of action of ACE inhibitors?
They block calcium channels in the heart.
They increase the excretion of sodium and water.
They inhibit the conversion of angiotensin I to angiotensin II.
They stimulate the release of aldosterone.
9. Describe the significance of beta-1 selective beta blockers in the
treatment of hypertension.
Beta-1 selective beta blockers are used only for heart failure and
have no effect on hypertension.
Beta-1 selective beta blockers increase heart rate and blood
volume, which can lead to higher blood pressure.
Beta-1 selective beta blockers work by dilating blood vessels,
which lowers blood pressure.
Beta-1 selective beta blockers primarily reduce heart rate and
myocardial contractility, making them effective in lowering
blood pressure.
10. What are the two non-DHP calcium channel blockers (CCBs)?
Amlodipine and Nifedipine
Lisinopril and Enalapril
Diltiazem and Verapamil
, Hydrochlorothiazide and Furosemide
11. In a patient with hypertension who is also at risk of hypokalemia, which
medication class would be most appropriate to consider for their
treatment?
Loop diuretics
Thiazide diuretics
Calcium channel blockers
Potassium-sparing diuretics
12. Which of the following correctly describes the action of Calcium
Channel Blockers in the treatment of hypertension?
NDHP CCBs act primarily on the kidney to lower blood pressure
DHP CCBs act primarily on the kidney to decrease BP
DHP CCBs act primarily in the vasculature to lower blood
pressure
Dihydropyridine calcium channel blockers (DHP CCBs) act
primarily on the heart to lower blood pressure
Non-dihydropyridine calcium channel blockers (NDHP CCBs)
act primarily in the vasculature to lower blood pressure
13. Describe how thiazide diuretics contribute to lowering blood pressure.
Thiazide diuretics directly relax blood vessel walls.
Thiazide diuretics lower blood pressure by reducing blood
volume and decreasing peripheral vascular resistance.
Thiazide diuretics increase heart rate, which lowers blood
pressure.
Thiazide diuretics increase sodium retention, which lowers blood
