COMPREHENSIVE EXAMINATION 2026
QUESTIONS WITH SOLUTIONS GRADED A+
◉What is an important purpose of conducting an interview prior to
beginning neuropsychological testing on an older adult suspected of
having dementia? Answer: To assess the patient's ability to
cooperate with the testing
◉A patient has unexplained weight loss and the provider notes
increased skin pigmentation on light-exposed skin folds along with
darkened palmar creases. Which laboratory test will the provider
NOT order? Answer: Serum cortisol
◉A patient with cancer is expected to require long-term pain
medication to manage cancer pain. Which agent will be best for this
patient? Answer: Morphine
◉A 16-year-old female has primary amenorrhea. A pregnancy test is
negative. Further testing reveals a normal TSH and an elevated
prolactin level. Which test will the provider order next? Answer:
Magnetic resonance imaging
,◉During a well-baby exam on a 9-month-old infant, the parent
reports that the baby always uses the left hand to pick up objects
and asks if the baby will be left-handed. What will the primary care
nurse practitioner do? Answer: Perform a careful assessment of fine
and gross motor skills.
◉An asymptomatic female learns that her boyfriend has gonorrhea
and asks about antibiotics. What will the provider recommend?
Answer: Empiric ceftriaxone and azithromycin
◉A 16-year-old sexually active female has symptoms of PID with
fever. Cultures are pending. For outpatient treatment, what will the
provider order? Answer: Rocephin, doxycycline, and metronidazole
◉A 30-year-old male patient has a positive leukocyte esterase and
nitrites on a random urine dipstick during a well patient exam. What
type of urinary tract infection does this represent? Answer:
Complicated
◉A woman who has had routine Pap tests all of her adult life has an
abnormal Pap with low-grade intraepithelial lesion. What will the
provider tell her about this result? Answer: Colposcopy with biopsy
is necessary
,◉A patient has bone pain and laboratory testing reveals an elevated
serum alkaline phosphatase (SAP). Which test can help distinguish
Paget's from malignant bone disease? Answer: Bone radiograph
◉What is the most important role of the primary care provider in
cancer management? Answer: Counseling about healthy practices to
reduce risk factors
◉A 35-year-old woman without a previous history of dysmenorrhea
reports lower pelvic pain and irregular bleeding between periods.
What is the initial action in managing this patient? Answer:
Performing an abdominal, pelvic, and rectovaginal examination
◉A patient being treated for cancer has had chemotherapy within
the past two weeks and comes to the primary care clinic with a fever
of 38.5° C. What is the initial action? Answer: Obtain a STAT CBC
with differential
◉What is a possible cause of decreased arousal, libido, and orgasm
in a postmenopausal woman? Answer: Diminished testosterone
◉A middle-school-age child is skipping school frequently and
getting poor grades since the child's father was killed while
deployed in the military. How will the primary care nurse
practitioner manage this situation? Answer: Refer the child to a
mental health specialist for evaluation and treatment.
, ◉A 40-year-old patient with primary hyperparathyroidism has
increased serum calcium 0.5 mg/dL above normal without signs of
nephrolithiasis. What is the recommended treatment for this
patient? Answer: Annual monitoring of calcium, creatinine, and
bone density
◉What is true about HPV infection in women? Answer: Most HPV
lesions will resolve spontaneously without causing cancer.
◉An elderly patient is diagnosed with osteoporosis. What is the
recommended treatment once the diagnosis is made? Answer:
Bisphosphonate therapy
◉A postmenopausal woman reports unilateral breast pain that she
describes as sharp and burning and localized to one area. A breast
examination reveals no dimpling, discharge, or masses. Which
diagnostic test will the provider order? Answer: Bilateral
mammography
◉An adolescent female has amenorrhea. The provider notes short
stature, neck webbing, and a pigeon chest deformity. Based on these
symptoms, what is the underlying disorder causing this patient's
amenorrhea? Answer: Turner's syndrome