SHEET 2026 UPDATED QUESTIONS AND
ANSWERS
◉HLA-B27. Answer: "PAIR":
-Psoriatic arthritis
-Ankylosing spondylitis
-IBD
-Reactive arthritis
◉Anti-CCP. Answer: Rheumatoid Arthritis
◉XR: narrowing of joint space. Answer: Rheumatoid arthritis
◉AntiSS-A (Ro) + AntiSS-B (La). Answer: Sjogren syndrome
◉(+) Schirmer test. Answer: Sjogren syndrome
◉joint pain + fever + butterfly rash. Answer: SLE
,◉Anti-ds DNA. Answer: SLE
◉(+) ANA. Answer: -SLE
_Scleroderma
◉Anticentromere Antibody. Answer: Limited Scleroderma (CREST)
◉Anti-topoisomerase (Anti-SCL-70 Ab). Answer: Diffuse
Scleroderma
◉hyperpigmentation, hyponatremia, hypoglycemia, hyperkalemia.
Answer: Addison's disease (primary adrenal insufficiency)
◉purple striae, proximal muscle weakness, moon facies, central
obesity, dorsocervical fat pad. Answer: Cushing syndrome
(hypercortosolism)
◉Bones, stones, abdominal groans, psychiatric overtones. Answer:
Hypercalcemia/Hyperparathyroidism
◉tingling, tetany, cataracts. Answer: hypoparathyroidism
◉Chovstek's sign. Answer: hypoparathyroidism
, (Tap facial nerve=> Muscle spasm)
◉Trousseau sign. Answer: hypoparathyroidism
(BP cuff --> spasm in hand and wrist)
◉abnormally large hands/feet; enlarged jaw. Answer:
acromegaly/gigantism
◉polyuria, polydipsia, high volume nocturia. Answer: diabetes
insipidus
◉bitemporal hemianopia. Answer: pituitary adenoma
◉(+) anti-TPO antibodies. Answer: Hashimoto's thyroiditis
◉Anti-thyrotropin antibodies. Answer: Grave's disease
◉inflamed, painFUL thyroid. Answer: subacute thyroiditis
(Quervain's)
◉Xray: lytic lesions, cotton wool appearance. Answer: Paget's
disease of the bone