While rational drug selection is based on the individual patient the aspect of rational drug selection
addressing disease-specific information by a national medical or nursing organization is
A. a guideline.
B. cost.
C. availability.
D. patient hepatic and renal function. - CORRECT ANSWER✅✅A. a guideline
Drugs that alter synaptic transmission are much more selective than those that alter axonal conduction,
why is this? - CORRECT ANSWER✅✅a drug that affects the axonal conduction - non-selective effect.
Drugs that alter synaptic transmission - very selective because of the differences in synapses and their
specific neurotransmitters
What is phenytoin used for? - CORRECT ANSWER✅✅Seizures
What should you monitor for with phenytoin? - CORRECT ANSWER✅✅Delayed hypersensitivity - even 1
month later
What is carbamazepine used for? - CORRECT ANSWER✅✅Seizures
What may cause carbamazepine levels to drop despite no other change? What to do? - CORRECT
ANSWER✅✅Autometabolization of drug. Increase dose.
What is the black box warning for carbamazepine? - CORRECT ANSWER✅✅Steven-Johnson Syndrome
& TENS
Monitoring for carbamazepine, and how often? - CORRECT ANSWER✅✅CBC, 3-4 times a year
, What population is most at risk for Steven-Johnson syndrome & TENS when taking carbamazepine? -
CORRECT ANSWER✅✅Asian patients
Main class of medication for depression? - CORRECT ANSWER✅✅Selective serotonin reuptake
inhibitors (SSRIs)
What to watch for with SSRIs? - CORRECT ANSWER✅✅Other medications that can cause serotonin
syndrome
What is lamictal used for? - CORRECT ANSWER✅✅Seizures
Patient on lamictal has fever, rash, swollen lymph nodes. What are we concerned for? - CORRECT
ANSWER✅✅Hypersensitivity in lamictal can lead to MODS
Patient on lamictal wants birth control. What do we need to change? - CORRECT ANSWER✅✅Increase
lamictal dose.
When will pt notice improvement after starting an SSRI? - CORRECT ANSWER✅✅4 weeks later
1st line medication for moderate generalized anxiety - CORRECT ANSWER✅✅Buspar (SNRI)
1st line med for classic migraines - CORRECT ANSWER✅✅Triptans
2nd line treatment for classic migraines - CORRECT ANSWER✅✅Prophylactic - propranolol
Why is important that NPs have the authority to prescribe? - CORRECT ANSWER✅✅Increase access to
healthcare
What must be done if a drug has a narrow therapeutic index? - CORRECT ANSWER✅✅Frequent serum
level monitoring