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PNB 2265 Final Exam| Study Guide| 2026 Graded A+

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What is true about the breakdown of red blood cells? Iron is carried through the plasma by transferrin Bilirubin is excreted in the urine Bilirubin is excreted in the bile Iron is carried through the plasma by transferrin ________________________________________ Adult hemoglobin is composed of what components? four heme groups two beta subunits two alpha subunits ________________________________________ Infant hemoglobin is composed of what components? four heme groups two alpha subunits two gamma subunits ________________________________________ What is hemoglobinuria characterized by? Large amounts of hemoglobin being expected in the urine ________________________________________ What kinds of cells are agranulocytes? Lymphocytes Monocytes ________________________________________ The most abundant leukocytes are ________ & the least abundant are ________ Neutrophil & Basophil ________________________________________ What is true about hemolytic disease? It is caused by anti-D antibodies crossing the placenta occurs in a woman with AB- blood Red blood cells in the fetus are being attacked by IgG antibodies from the mother ________________________________________ What is true about myeloid stem cells? stimulation by EPO causes them to differentiate into proerythroblasts they have ribosomes they have a nucleus ________________________________________ Where does Erythropoietin come from? The kidney, to increase RBC production ________________________________________ In the process of hemostasis, what is Factor-X function? Activates a sequence of enzymatic reactions that produce the coagulation phase of hemostasis ________________________________________

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PNB 2265
Course
PNB 2265

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PCB 3233



PNB 2265 Final Exam| Study Guide| 2026
Graded A+


What is true about the breakdown of red blood cells?

Iron is carried through the plasma by transferrin

Bilirubin is excreted in the urine

Bilirubin is excreted in the bile

Iron is carried through the plasma by transferrin



Adult hemoglobin is composed of what components?

four heme groups

two beta subunits

two alpha subunits



Infant hemoglobin is composed of what components?

four heme groups

two alpha subunits

two gamma subunits



What is hemoglobinuria characterized by?
Large amounts of hemoglobin being expected in the urine




PCB 3233

,PCB 3233


What kinds of cells are agranulocytes?

Lymphocytes
Monocytes



The most abundant leukocytes are ________ & the least abundant are ________
Neutrophil & Basophil



What is true about hemolytic disease?

It is caused by anti-D antibodies crossing the placenta

occurs in a woman with AB- blood

Red blood cells in the fetus are being attacked by IgG antibodies from the mother



What is true about myeloid stem cells?

stimulation by EPO causes them to differentiate into proerythroblasts

they have ribosomes

they have a nucleus



Where does Erythropoietin come from?
The kidney, to increase RBC production



In the process of hemostasis, what is Factor-X function?
Activates a sequence of enzymatic reactions that produce the coagulation phase of
hemostasis




PCB 3233

, PCB 3233


In the process of hemostasis, what is Tissue Factor's function?
Serves as the entry point to the extrinsic pathway



In the process of hemostasis, what is the function of Thrombin?
Converts Fibrinogen to Fibrin



In the process of hemostasis, what is the function of Collagen?
Serves as the starting point of the intrinsic pathway- activates inactive clotting factors
when blood leaks from the blood vessel



What is hemostasis?
The process of stopping blood loss



What are the phases of hemostasis?

1. Vascular spasm
2. Platelet phase
3. Coagulation



How is Thrombin formed?
Either by the extrinsic or intrinsic pathways



How is the extrinsic pathway initiated?
Via tissue factors that come from damaged endothelial cells and then goes to the
common pathway to form thrombin




PCB 3233

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