PNB 2265 Final Exam| Study Guide| 2026
Graded A+
What is true about the breakdown of red blood cells?
Iron is carried through the plasma by transferrin
Bilirubin is excreted in the urine
Bilirubin is excreted in the bile
Iron is carried through the plasma by transferrin
Adult hemoglobin is composed of what components?
four heme groups
two beta subunits
two alpha subunits
Infant hemoglobin is composed of what components?
four heme groups
two alpha subunits
two gamma subunits
What is hemoglobinuria characterized by?
Large amounts of hemoglobin being expected in the urine
PCB 3233
,PCB 3233
What kinds of cells are agranulocytes?
Lymphocytes
Monocytes
The most abundant leukocytes are ________ & the least abundant are ________
Neutrophil & Basophil
What is true about hemolytic disease?
It is caused by anti-D antibodies crossing the placenta
occurs in a woman with AB- blood
Red blood cells in the fetus are being attacked by IgG antibodies from the mother
What is true about myeloid stem cells?
stimulation by EPO causes them to differentiate into proerythroblasts
they have ribosomes
they have a nucleus
Where does Erythropoietin come from?
The kidney, to increase RBC production
In the process of hemostasis, what is Factor-X function?
Activates a sequence of enzymatic reactions that produce the coagulation phase of
hemostasis
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, PCB 3233
In the process of hemostasis, what is Tissue Factor's function?
Serves as the entry point to the extrinsic pathway
In the process of hemostasis, what is the function of Thrombin?
Converts Fibrinogen to Fibrin
In the process of hemostasis, what is the function of Collagen?
Serves as the starting point of the intrinsic pathway- activates inactive clotting factors
when blood leaks from the blood vessel
What is hemostasis?
The process of stopping blood loss
What are the phases of hemostasis?
1. Vascular spasm
2. Platelet phase
3. Coagulation
How is Thrombin formed?
Either by the extrinsic or intrinsic pathways
How is the extrinsic pathway initiated?
Via tissue factors that come from damaged endothelial cells and then goes to the
common pathway to form thrombin
PCB 3233