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NR 507 Exam Questions: Advanced Pathophysiology – Complete Study Guide with Correct Verified Answers | Latest Exam Update | Tested & Approved

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Ace NR 507 Advanced Pathophysiology with this comprehensive exam study guide featuring complete questions and correct verified answers. Covering essential pathophysiology topics including respiratory disorders (asthma, bronchitis, anticholinergic drugs, alveolar hyperinflation, acid-base disorders), cardiovascular disorders (cardiac output, preload, afterload, heart failure pathophysiology, left-sided and right-sided heart failure, valvular stenosis, cardiac cycle), hematologic disorders (anemia, hemolytic anemia, polycythemia, hematopoiesis, erythropoietin), renal disorders (kidney anatomy and physiology, glomerulonephritis, acute kidney injury, chronic kidney disease, kidney stones, benign prostatic hyperplasia, polycystic kidney disease), and immune function. Perfect for graduate nursing students, NP students, and those preparing for advanced pathophysiology exams.

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NR 507 EXAM QUESTIONS WITH

CORRECT VERIFIED ANSWERS LATEST
EXAM UPDATE TESTED AND APPROVED!!!


What do anticholinergics do in the lungs? - ANS✔✔ -- These drugs block the
effects of the parasympathetic nervous system

- increasing bronchodilation

MOA of anticholinergic drugs for asthma - ANS✔✔ -- the parasympathetic
system is stimulated by the vagal nerve to release acetylcholine which binds to
the cholinergic receptors of the respiratory tract to cause bronchial constriction
= decreased airflow

- blocking the cholinergic receptors prevents acetylcholine binding
preventing the bronchial constriction

bronchitis - ANS✔✔---inflammation of the bronchial tubes

3 characteristics of bronchitis - ANS✔✔---bronchial inflammation
hypersecretion of mucus chronic productive cough for at least 3 consecutive
months for at least 2 successive years

Perfusion - ANS✔✔---The supply of oxygen to and removal of wastes from the
cells and tissues of the body as a result of the flow of blood through the
capillaries.



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,results of chronic bronchitis/ low perfusion - ANS✔✔---cyanosis right to left
shunting chronic hypoxemia

Why is there cyanosis with chronic bronchitis - ANS✔✔---there is hypoxia due
to unfavorable conditions for gas exchange

Right to left shunting - ANS✔✔---when blood passes from the right ventricle
through the lungs and to the left ventricle without perfusion

Causes of bronchitis - ANS✔✔ --- long term exposure to environmental irritants

-repeated episodes of acute infection (RSV infection in early infancy)

-Factors affecting gestational childhood lung development (preterm birth)

Pathogenesis of bronchitis - ANS✔✔ --- Exposure to airborne irritants

- Irritant activates bronchial smooth muscle constriction and mucus
secretion

- Triggers release of inflammatory mediators from immune cells located in
the lamina propria

most common irritant with bronchitis is? - ANS✔✔ -- tobacco product smoke

what does long term exposure to irritants promote in bronchitis? (5) - ANS✔✔--
-- smooth muscle hypertrophy

- hypertrophy and hyperplasia of goblet cells

- epithelial cell metaplasia

- migration of more WBC to site

- thickening and rigidity of bronchial basement membrane

What does smooth muscle hypertrophy do in lungs? - ANS✔✔---causes
increased bronchoconstriction
Page 2 of 25

, Hypertrophy and hyperplasia of goblet cells do what in the bronchials -
ANS✔✔--- promotes hypersecretion of mucus



Asthma - ANS✔✔---Chronic disease due to bronchoconstriction and an
excessive inflammatory response in the bronchioles

What are 5 s/s of asthma - ANS✔✔---coughing wheezing shortness of breath
rapid breathing chest tightness

Pathophysiology of asthma (5) - ANS✔✔---- airway inflammation, bronchial
hyper- reactivity and smooth muscle spasm

-excess mucus production and accumulation

-hypertrophy of bronchial smooth muscle

-airflow obstruction

-decreased alveolar ventilation

Bronchioles - ANS✔✔ --- smaller passageways that originate from the bronchi
that become the alveoli

3 layers of the bronchioles - ANS✔✔ -- innermost layer

middle layer - lamina propria outermost layer

lamina propria - ANS✔✔---the middle layer of the bronchioles

structure of the lamina propria - ANS✔✔---embedded with connective tissue
cells and immune cells

purpose of the lamina propria - ANS✔✔---white blood cells are present to help
protect the airways


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