Test Bank - for Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 9th Edition, by Nader Rifai, Chapter 1-49 |All Chapters

,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 9th Edition Test Bank
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Table of contents:
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I. Principles Of Laboratory Medicine
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Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
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Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
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Chapter 3. Clinical Evaluation of Methods
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Chapter 4. Evidence-Based Laboratory Medicine
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Chapter 5. Establishment and Use of Reference Values
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Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
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Chapter 7. Quality Management
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II. Analytical Techniques And Instrumentation
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Chapter 8. Principles of Basic Techniques and Laboratory Safety
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Chapter 9. Optical Techniques
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Chapter 10. Electrochemistry and Chemical Sensors
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Chapter 11. Electrophoresis
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Chapter 12. Chromatography
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Chapter 13. Mass Spectrometry
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Chapter 14. Enzyme and Rate Analyses
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Chapter 15. Immunochemical Techniques
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Chapter 16 Automation +f +f



Chapter 17. Point-of-Care Instrumentation
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III. Analytes
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Chapter 18. Amino Acids, Peptides, and Proteins
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Chapter 19. Serum Enzymes
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Chapter 20. Tumor Markers and Cancer Genes
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Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
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Chapter 22. Carbohydrates
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Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
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Chapter 24. Electrolytes and Blood Gases
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Chapter 25. Hormones +f +f



Chapter 26. Catecholamines and Serotonin
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Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter 28. Hemoglobin, Iron, and Bilirubin
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Chapter 29. Porphyrins and Porphyrias
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Chapter 30. Therapeutic Drugs and Their Management
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Chapter 31. Clinical Toxicology
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Chapter 32. Toxic Metals
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IV. Pathophysiology
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Chapter 33. Diabetes +f +f

,Chapter 34. Cardiovascular Disease
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Chapter 35. Kidney Disease
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Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
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Chapter 37. Liver Disease
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Chapter 38. Gastrointestinal and Pancreatic Diseases
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Chapter 39. Disorders of Bone and Mineral Metabolism
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Chapter 40. Disorders of the Pituitary Gland
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Chapter 41. Disorders of the Adrenal Cortex
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Chapter 42. Thyroid Disorders
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Chapter 43. Reproduction-Related Disorders
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Chapter 44. Pregnancy and Prenatal Testing
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Chapter 45. Newborn Screening and Inborn Errors of Metabolism
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Chapter 46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter 47. Principles of Molecular Biology
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Chapter 48. Nucleic Acid Techniques and Applications
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Chapter 49. Genomes and Nucleic Acid Alterations
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, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine TestBan
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k

MULTIPLE CHOICE +f




1. An individual working in a clinical chemistry laboratory is married to a sales representativ
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e who works for a company that sells chemistry laboratory supplies. When the laboratory
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manager requests a list of needed supplies, cost of supplies, and vendors, this individual onl
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y recommends the spouse’s company as the vendor. This is considered to be a(n):
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a. accounting issue. +f


b. possible conflict of interest. +f +f +f


c. maintenance of confidentiality issue. +f +f +f


d. problem with resource allocation. +f +f +f




ANS: B +f


Concern has been raised over the interrelationships between practitioners in the medical field
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and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufactur
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ers and providers of diagnostic equipment and supplies. These concerns led the National Inst
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itutes of Health (NIH) in 1995 to require official institutional review of financial disclosure
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by researchers and management of situations in which disclosure indicates potential conflicts
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of interest.
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DIF: 1 REF: + f Page 4-5 +f OBJ: 6 | 7 +f +f +f




2. A patient visits her physician stating that her prescribed painkiller is not working to reduc
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e the pain following her recent surgery. A friend of the patient claims that the same painkil
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ler “worked wonders” to reduce her pain after the same surgery. The physician states that
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the difference in the effect of the drug might be caused by
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, which is studied in pharmacog +f +f +f +f +f


enetics.
a. epidemiology
b. an inherited disease +f +f


c. a conflict of interest+f +f +f


d. a genetic variation in drug-metabolizing enzymes
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ANS: D +f


Pharmacogenetics is the study of the genetic variation of drug metabolism between indivi +f +f +f +f +f +f +f +f +f +f +f +f


duals.

DIF: 1 REF: + f+ f Page 3 +f OBJ: 1 +f




3. John works in a molecular diagnostics laboratory and receives a blood sample that has th
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e name of a close friend printed on the bar-
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coded label. The genetic test that is ordered on the friend’s sample would provide diagnos
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tic information about a disorder that has a poor prognosis, and the test is usually perform
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ed by John. He asks a fellow employee to analyze the sample for him and not divulge the
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results. This ethical issue concerns:
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a. confidentiality of patient genetic and medical information. +f +f +f +f +f +f


b. a conflict of interest.
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c. resource allocation. +f


d. diagnostic accuracy. +f