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Suffix -cillin; Example: Amoxicillin; Key Adverse Effect:
Allergic reactions (anaphylaxis). Cephalosporins -
ANSWER//Prefix cef- / ceph-; Example: Ceftriaxone; Key
Adverse Effect: Nephrotoxicity, PMC. Tetracyclines -
ANSWER//Suffix -cycline; Example: Doxycycline; Key
Adverse Effect: Photosensitivity, teeth discoloration.
Macrolides - ANSWER//Suffix -thromycin; Example:
Azithromycin; Key Adverse Effect: QT prolongation,
hepatotoxicity. Aminoglycosides - ANSWER//Suffix -micin
/ -mycin; Example: Gentamicin; Key Adverse Effect:
Nephrotoxicity, ototoxicity. Fluoroquinolones -
ANSWER//Suffix -floxacin; Example: Ciprofloxacin; Key
Adverse Effect: Tendon rupture (BBW). Sulfonamides -
ANSWER//Prefix sulfa-; Example: Sulfamethoxazole; Key
Adverse Effect: Crystalluria, Stevens-Johnson.
Carbapenems - ANSWER//Suffix -penem; Example:
Imipenem; Key Adverse Effect: Seizures, PMC.
Clindamycin - ANSWER//No suffix; Example: Clindamycin;
Key Adverse Effect: C. diff colitis (BBW). Vancomycin -
ANSWER//Suffix -mycin (exception); Example:
Vancomycin; Key Adverse Effect: Red Man Syndrome.
Antituberculars - ANSWER//Prefix rif- (rifamycins);
Example: Rifampin; Key Adverse Effect: Orange
secretions, hepatotoxicity. Antifungals - ANSWER//Suffix -
azole; Example: Fluconazole; Key Adverse Effect:
Hepatotoxicity, Stevens-Johnson. Antifungals (Polyenes) -
ANSWER//No suffix; Example: Amphotericin B; Key
Adverse Effect: Nephrotoxicity, infusion reactions.
Antiprotozoals - ANSWER//Suffix -nidazole; Example:
,Metronidazole; Key Adverse Effect: Disulfiram-like
reaction with alcohol. Antimalarials - ANSWER//Suffix -
quine; Example: Chloroquine; Key Adverse Effect: Visual
disturbances. Anthelmintics - ANSWER//Suffix -bendazole;
Example: Mebendazole; Key Adverse Effect: GI upset.
Herpes Antivirals - ANSWER//Suffix -cyclovir / -ciclovir;
Example: Acyclovir; Key Adverse Effect: Nephrotoxicity
(IV). Influenza Antivirals - ANSWER//Suffix -amivir;
Example: Oseltamivir; Key Adverse Effect:
Neuropsychiatric effects, bronchospasm. Hepatitis
Antivirals - ANSWER//Suffix -vir; Example: Tenofovir; Key
Adverse Effect: Nephrotoxicity, lactic acidosis. Hepatitis
(Interferons) - ANSWER//No suffix; Example: PegIFN alfa-
2a; Key Adverse Effect: Flu-like symptoms,
myelosuppression. Hepatitis C Antivirals -
ANSWER//Suffix -virin; Example: Ribavirin; Key Adverse
Effect: Hemolytic anemia, teratogenic. COVID Antivirals -
ANSWER//Suffix -vir; Example: Remdesivir; Key Adverse
Effect: Elevated LFTs, nausea. RSV Monoclonal
Antibodies - ANSWER//Suffix -mab; Example: Palivizumab;
Key Adverse Effect: Injection site reactions. Isoniazid -
What sets it apart? - ANSWER//First-line TB drug; inhibits
mycolic acid synthesis; bactericidal for active TB,
bacteriostatic for dormant. Isoniazid - Priority nursing
action? - ANSWER//Give on empty stomach; enforce
compliance; supplement Vitamin B6 to prevent neuropathy.
Isoniazid - Common adverse effects? -
ANSWER//Hepatotoxicity, peripheral neuropathy, optic
neuritis, psychosis, seizures. Isoniazid -
Labs/Assessments? - ANSWER//Monitor liver enzymes
(ALT, AST), chest X-ray, sputum cultures. Isoniazid -
Patient teaching? - ANSWER//Take as prescribed for full
course, avoid alcohol/tyramine foods, report
numbness/tingling, orange body fluids possible. Rifampin -
What sets it apart? - ANSWER//First-line TB drug; broad
spectrum; bactericidal; turns body fluids orange-red.
Rifampin - Priority nursing action? - ANSWER//Give on
, empty stomach; enforce compliance. Rifampin - Common
adverse effects? - ANSWER//Hepatotoxicity, GI upset,
orange secretions. Rifampin - Labs/Assessments? -
ANSWER//Monitor liver enzymes, CBC. Rifampin - Patient
teaching? - ANSWER//Warn about harmless orange
secretions, may reduce effectiveness of oral
contraceptives, avoid alcohol. Pyrazinamide - What sets it
apart? - ANSWER//First-line TB drug; used in combination
therapy. Pyrazinamide - Priority nursing action? -
ANSWER//Monitor for hepatotoxicity and gout symptoms.
Pyrazinamide - Common adverse effects? -
ANSWER//Hepatotoxicity, hyperuricemia, joint pain.
Pyrazinamide - Labs/Assessments? - ANSWER//Liver
function tests, uric acid levels. Pyrazinamide - Patient
teaching? - ANSWER//Report joint pain or yellowing of
eyes/skin, avoid alcohol. Ethambutol - What sets it apart?
- ANSWER//First-line TB drug; bacteriostatic; associated
with optic neuritis. Ethambutol - Priority nursing action? -
ANSWER//Baseline and periodic vision testing.
Ethambutol - Common adverse effects? - ANSWER//Optic
neuritis, color blindness, peripheral neuropathy.
Ethambutol - Labs/Assessments? - ANSWER//Visual
acuity, color discrimination, liver enzymes. Ethambutol -
Patient teaching? - ANSWER//Report visual changes
immediately, take as prescribed. Amphotericin B - What
sets it apart? - ANSWER//Polyene antifungal; drug of
choice for serious systemic mycoses. Amphotericin B -
Priority nursing action? - ANSWER//Infuse slowly;
premedicate to reduce infusion reactions; monitor renal
function. Amphotericin B - Common adverse effects? -
ANSWER//Nephrotoxicity, ototoxicity, hypokalemia, fever,
chills, hypotension, dysrhythmias. Amphotericin B -
Labs/Assessments? - ANSWER//BUN, creatinine,
potassium, IV site. Amphotericin B - Patient teaching? -
ANSWER//Report decreased urine, hearing changes, or
palpitations. Fluconazole - What sets it apart? -
ANSWER//Azole antifungal; drug of choice for Candida