Summary Advanced Pathophysiology (NR-507)

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NR507 week5 depression


Advanced Pathophysiology (Chamberlain University)




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, lOMoARcPSD|47245706




NR507 week5 depression




Downloaded by Herbert Macharia ()

, lOMoARcPSD|47245706




Serotonin

Synthesis and Release: Serotonin is synthesized in the neurons from the
amino acid tryptophan. Once synthesized, serotonin is stored in vesicles
within the nerve terminals.

Release and Reuptake: When a nerve impulse reaches the end of a
neuron, serotonin is released into the synapse (the gap between neurons).
After release, some of the serotonin binds to receptors on the postsynaptic
neuron, transmitting the signal. The remaining serotonin is taken back up
into the presynaptic neuron through a process called reuptake, where it can
be recycled.

Receptors: Serotonin binds to specific receptors on the postsynaptic
neuron. There are various subtypes of serotonin receptors (e.g., 5-HT1, 5-




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